产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Nanog (D73G4) XP® Rabbit mAb
目录 :
4903
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D73G4
反应物种 :
African green monkey, common marmoset, 人类, 小鼠, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片
文章摘录数: 68
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 猕猴; 1:400; 图 2c
Rodriguez Polo I, Mißbach S, Petkov S, Mattern F, Maierhofer A, Grządzielewska I, et al. A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation. Sci Rep. 2021;11:15439 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1b
Yamamura Y, Furuichi K, Murakawa Y, Hirabayashi S, Yoshihara M, Sako K, et al. Identification of candidate PAX2-regulated genes implicated in human kidney development. Sci Rep. 2021;11:9123 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 5b
Stauske M, Rodriguez Polo I, Haas W, Knorr D, Borchert T, Streckfuss Bömeke K, et al. Non-Human Primate iPSC Generation, Cultivation, and Cardiac Differentiation under Chemically Defined Conditions. Cells. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4b
Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5a
Gunne Braden A, Sullivan A, Gharibi B, Sheriff R, Maity A, Wang Y, et al. GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells. Cell Stem Cell. 2020;26:693-706.e9 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Chen J, Chen S, Zhuo L, Zhu Y, Zheng H. Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer. Cell Death Dis. 2020;11:173 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Zang M, Guo J, Liu L, Jin F, Feng X, An G, et al. Cdc37 suppression induces plasma cell immaturation and bortezomib resistance in multiple myeloma via Xbp1s. Oncogenesis. 2020;9:31 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 2e
Chen Y, Li Y, Chou C, Chiew M, Huang H, Ho J, et al. Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458. Sci Adv. 2020;6:eaay0264 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5d
Marin Navarro A, Pronk R, van der Geest A, Oliynyk G, Nordgren A, Arsenian Henriksson M, et al. p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids. Cell Death Dis. 2020;11:52 pubmed 出版商
  • 免疫细胞化学; 人类; 1:800; 图 s3a
Rahman M, Wruck W, Spitzhorn L, Nguyen L, Bohndorf M, Martins S, et al. The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells. Sci Rep. 2020;10:739 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Zhan Y, Li R, Feng C, Li X, Huang S, Wang L, et al. Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2. Biomed Pharmacother. 2020;121:109602 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, et al. ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. Mol Ther Oncolytics. 2019;14:299-312 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5b
  • 免疫印迹; 人类; 图 2a, 2h
Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b
Quintero C, Laursen K, Mongan N, Luo M, Gudas L. CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation. J Mol Biol. 2018;430:4168-4182 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 5d
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s1
Aguisanda F, Yeh C, Chen C, Li R, Beers J, Zou J, et al. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet J Rare Dis. 2017;12:120 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s1a
Jeziorowska D, Fontaine V, Jouve C, Villard E, Dussaud S, Akbar D, et al. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1g
Uhlin E, Rönnholm H, Day K, Kele M, Tammimies K, Bölte S, et al. Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions. Stem Cell Res. 2017;18:22-25 pubmed 出版商
  • 免疫细胞化学; 人类; 1:800; 图 4B
  • 免疫细胞化学; African green monkey; 1:800; 图 1B
Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, et al. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS ONE. 2017;12:e0171947 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
Bharathan S, Manian K, Aalam S, Palani D, Deshpande P, Pratheesh M, et al. Systematic evaluation of markers used for the identification of human induced pluripotent stem cells. Biol Open. 2017;6:100-108 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
  • 免疫印迹; 人类; 1:1000; 图 2a
Prieto P, Fernandez Velasco M, Fernández Santos M, Sanchez P, Terrón V, Martín Sanz P, et al. Cell Expansion-Dependent Inflammatory and Metabolic Profile of Human Bone Marrow Mesenchymal Stem Cells. Front Physiol. 2016;7:548 pubmed
  • 流式细胞仪; 人类; 1:200; 图 1b
Zhu L, Gómez Durán A, Saretzki G, Jin S, Tilgner K, Melguizo Sanchís D, et al. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J Cell Biol. 2016;215:187-202 pubmed
  • 免疫组化; 人类; 1:200; 图 1h
Kele M, Day K, Rönnholm H, Schuster J, Dahl N, Falk A. Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions. Stem Cell Res. 2016;17:474-478 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Lv D, Yu S, Ping Y, Wu H, Zhao X, Zhang H, et al. A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics. Oncotarget. 2016;7:56904-56914 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 1d
Baillie R, Itinteang T, Yu H, Brasch H, Davis P, Tan S. Cancer stem cells in moderately differentiated oral tongue squamous cell carcinoma. J Clin Pathol. 2016;69:742-4 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 S1B
Stratigopoulos G, Burnett L, Rausch R, Gill R, Penn D, Skowronski A, et al. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. J Clin Invest. 2016;126:1897-910 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:100; 图 5b
  • 免疫印迹; 人类; 图 5c
Wang X, Jung Y, Jun S, Lee S, Wang W, Schneider A, et al. PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness. Nat Commun. 2016;7:10633 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Kyttälä A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy K, et al. Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential. Stem Cell Reports. 2016;6:200-12 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1e
Balboa D, Weltner J, Eurola S, Trokovic R, Wartiovaara K, Otonkoski T. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation. Stem Cell Reports. 2015;5:448-59 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kawamura N, Nimura K, Nagano H, Yamaguchi S, Nonomura N, Kaneda Y. CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells. Oncotarget. 2015;6:22361-74 pubmed
  • 免疫组化-石蜡切片; 人类; 图 3
  • 免疫印迹; 人类
Palla A, Piazzolla D, Alcazar N, Cañamero M, Graña O, Gómez López G, et al. The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Sci Rep. 2015;5:10205 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 5
Zhou H, Martínez H, Sun B, Li A, Zimmer M, Katsanis N, et al. Rapid and Efficient Generation of Transgene-Free iPSC from a Small Volume of Cryopreserved Blood. Stem Cell Rev. 2015;11:652-65 pubmed 出版商
  • 免疫细胞化学; common marmoset; 1:300; 图 2
Debowski K, Warthemann R, Lentes J, Salinas Riester G, Dressel R, Langenstroth D, et al. Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. PLoS ONE. 2015;10:e0118424 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
Wilson P, Payne T. Genetic reprogramming of human amniotic cells with episomal vectors: neural rosettes as sentinels in candidate selection for validation assays. Peerj. 2014;2:e668 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, et al. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture. PLoS ONE. 2014;9:e112900 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Xie Y, Lu W, Liu S, Yang Q, Carver B, Li E, et al. Crosstalk between nuclear MET and SOX9/?-catenin correlates with castration-resistant prostate cancer. Mol Endocrinol. 2014;28:1629-39 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 7
  • 免疫印迹; 小鼠; 1:1000; 图 7
Piazzolla D, Palla A, Pantoja C, Canamero M, de Castro I, Ortega S, et al. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia. Nat Commun. 2014;5:4226 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Krutá M, Šeneklová M, Raška J, Salykin A, Zerzankova L, Pesl M, et al. Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterparts. Stem Cells Dev. 2014;23:2443-54 pubmed 出版商
  • 免疫组化; 人类; 1:300
  • 免疫印迹; 人类; 1:1000
Chen W, Ho C, Chang Y, Chen H, Lin C, Ling T, et al. Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling. Nat Commun. 2014;5:3472 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:800
Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, et al. A single-cell and feeder-free culture system for monkey embryonic stem cells. PLoS ONE. 2014;9:e88346 pubmed 出版商
  • 免疫印迹; 人类
Zhang J, Espinoza L, Kinders R, Lawrence S, Pfister T, Zhou M, et al. NANOG modulates stemness in human colorectal cancer. Oncogene. 2013;32:4397-405 pubmed 出版商
Aban C, Lombardi A, Neiman G, Biani M, La Greca A, Waisman A, et al. Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT. Sci Rep. 2021;11:2048 pubmed 出版商
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed 出版商
Kozono S, Lin Y, Seo H, Pinch B, Lian X, Qiu C, et al. Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nat Commun. 2018;9:3069 pubmed 出版商
Ooki A, Dinalankara W, Marchionni L, Tsay J, Goparaju C, Maleki Z, et al. Epigenetically regulated PAX6 drives cancer cells toward a stem-like state via GLI-SOX2 signaling axis in lung adenocarcinoma. Oncogene. 2018;37:5967-5981 pubmed 出版商
Jonikas M, Madill M, Mathy A, Zekoll T, Zois C, Wigfield S, et al. Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1. Ann Neurol. 2018;83:915-925 pubmed 出版商
Bratkovic T, Modic M, Camargo Ortega G, Drukker M, Rogelj B. Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA. Sci Rep. 2018;8:5101 pubmed 出版商
Ooki A, Begum A, Marchionni L, Vandenbussche C, Mao S, Kates M, et al. Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells. Int J Cancer. 2018;143:113-126 pubmed 出版商
Maiti S, Mondal S, Satyavarapu E, Mandal C. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation. Cell Death Dis. 2017;8:e2926 pubmed 出版商
Buonocore F, Kühnen P, Suntharalingham J, Del Valle I, Digweed M, Stachelscheid H, et al. Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest. 2017;127:1700-1713 pubmed 出版商
Guo J, Hsu H, Tyan S, Li F, Shew J, Lee W, et al. Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner. Oncogene. 2017;36:2457-2471 pubmed 出版商
Lillo M, Nichols C, Perry C, Runke S, Krutilina R, Seagroves T, et al. Methylparaben stimulates tumor initiating cells in ER+ breast cancer models. J Appl Toxicol. 2017;37:417-425 pubmed 出版商
Cigognini D, Gaspar D, Kumar P, Satyam A, Alagesan S, Sanz Nogués C, et al. Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - A step closer to physiologically relevant in vitro organogenesis. Sci Rep. 2016;6:30746 pubmed 出版商
Miyatake Y, Sheehy N, Ikeshita S, Hall W, Kasahara M. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like ATL cells in an NF-κB- and vimentin-dependent manner. Cancer Lett. 2015;357:355-63 pubmed 出版商
Aeckerle N, Drummer C, Debowski K, Viebahn C, Behr R. Primordial germ cell development in the marmoset monkey as revealed by pluripotency factor expression: suggestion of a novel model of embryonic germ cell translocation. Mol Hum Reprod. 2015;21:66-80 pubmed 出版商
Kregel S, Szmulewitz R, Vander Griend D. The pluripotency factor Nanog is directly upregulated by the androgen receptor in prostate cancer cells. Prostate. 2014;74:1530-43 pubmed 出版商
Chen W, Liu J, Zhang L, Xu H, Guo X, Deng S, et al. Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique. Sci Rep. 2014;4:5404 pubmed 出版商
Miettinen M, Wang Z, McCue P, Sarlomo Rikala M, Rys J, Biernat W, et al. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014;38:410-20 pubmed 出版商
Vuoristo S, Toivonen S, Weltner J, Mikkola M, Ustinov J, Trokovic R, et al. A novel feeder-free culture system for human pluripotent stem cell culture and induced pluripotent stem cell derivation. PLoS ONE. 2013;8:e76205 pubmed 出版商
Rybak A, Tang D. SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cell Signal. 2013;25:2734-42 pubmed 出版商
Romorini L, Riva D, Bluguermann C, Videla Richardson G, Scassa M, Sevlever G, et al. Effect of antibiotics against Mycoplasma sp. on human embryonic stem cells undifferentiated status, pluripotency, cell viability and growth. PLoS ONE. 2013;8:e70267 pubmed 出版商
Kregel S, Kiriluk K, Rosen A, Cai Y, Reyes E, Otto K, et al. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. PLoS ONE. 2013;8:e53701 pubmed 出版商
Singh S, Trevino J, Bora Singhal N, Coppola D, Haura E, Altiok S, et al. EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer. Mol Cancer. 2012;11:73 pubmed 出版商
Polak U, Hirsch C, Ku S, GOTTESFELD J, Dent S, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. J Vis Exp. 2012;: pubmed 出版商
Chae H, Lee M, Broxmeyer H. 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation. Stem Cells. 2012;30:140-9 pubmed 出版商
Ledur P, Villodre E, Paulus R, Cruz L, Flores D, Lenz G. Extracellular ATP reduces tumor sphere growth and cancer stem cell population in glioblastoma cells. Purinergic Signal. 2012;8:39-48 pubmed 出版商
产品信息
SKU号 :
4903S
产品名称 :
Nanog (D73G4) XP® Rabbit mAb
规格 :
100微升
Price-(USD) :
260美元
物种x :
H, (Mk)
应用 :
流式细胞仪
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
42
宿主 :
靶标 :
Nanog
最初蛋白 :
NANOG
别名 :
Homeobox protein NANOG,Homeobox transcription factor Nanog,NANOG,Nanog homeobox,hNanog,homeobox transcription factor Nanog-delta 48
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。