产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
53BP1抗体
目录 :
4937
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, reverse phase protein lysate microarray, 其他
文章摘录数: 38
出版应用/物种/样品/稀释参考文献
  • 免疫细胞化学; 人类; 图 2e
  • 免疫细胞化学; 小鼠; 图 6e
Kannan A, Bhatia K, Branzei D, Gangwani L. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy. Nucleic Acids Res. 2018;46:8326-8346 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫组化; 人类; 1:300; 图 4h
Collin G, Huna A, Warnier M, Flaman J, Bernard D. Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence. Cell Death Dis. 2018;9:259 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 5c
Nagano T, Nakashima A, Onishi K, Kawai K, Awai Y, Kinugasa M, et al. Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. J Cell Sci. 2017;130:1413-1420 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4a
Li Y, Shen Y, Hohensinner P, Ju J, Wen Z, Goodman S, et al. Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis. Immunity. 2016;45:903-916 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4b
  • 免疫印迹; 人类; 图 s1e
Bridges K, Chen X, Liu H, Rock C, Buchholz T, Shumway S, et al. MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Oncotarget. 2016;7:71660-71672 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1a
Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed
  • 免疫印迹; 人类; 图 2
Yalon M, Tuval Kochen L, Castel D, Moshe I, Mazal I, Cohen O, et al. Overcoming Resistance of Cancer Cells to PARP-1 Inhibitors with Three Different Drug Combinations. PLoS ONE. 2016;11:e0155711 pubmed 出版商
  • reverse phase protein lysate microarray; 小鼠; 图 s1.b,c
Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Choi Y, Meghani K, Brault M, Leclerc L, He Y, Day T, et al. Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. Cell Rep. 2016;14:429-439 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4a
Pellegrini C, Columbaro M, Capanni C, D Apice M, Cavallo C, Murdocca M, et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget. 2015;6:29914-28 pubmed 出版商
  • 免疫细胞化学; 人类
Bouley J, Saad L, Grall R, Schellenbauer A, Biard D, Paget V, et al. A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines. Oncotarget. 2015;6:27980-8000 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s4
Ip L, Poulogiannis G, Viciano F, Sasaki J, Kofuji S, Spanswick V, et al. Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. Oncotarget. 2015;6:10548-62 pubmed
  • 免疫细胞化学; 人类; 图 1
Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:350
Laos M, Anttonen T, Kirjavainen A, af Hällström T, Laiho M, Pirvola U. DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells. Aging (Albany NY). 2014;6:496-510 pubmed
  • 免疫细胞化学; 小鼠; 1:200; 图 s3
Schröder Heurich B, Wieland B, Lavin M, Schindler D, Dork T. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J. 2014;28:1331-41 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Dai C, Sun F, Zhu C, Hu X. Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors. PLoS ONE. 2013;8:e63054 pubmed 出版商
Guirouilh Barbat J, Gelot C, Xie A, Dardillac E, Scully R, Lopez B. 53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks. PLoS Genet. 2016;12:e1006230 pubmed 出版商
Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed 出版商
Tiwana G, Prevo R, Buffa F, Yu S, Ebner D, Howarth A, et al. Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen. Oncotarget. 2015;6:5978-89 pubmed
Sone K, Piao L, Nakakido M, Ueda K, Jenuwein T, Nakamura Y, et al. Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. Nat Commun. 2014;5:5691 pubmed 出版商
Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed 出版商
Park J, Tougeron D, Huang S, Okamoto K, Sinicrope F. Beclin 1 and UVRAG confer protection from radiation-induced DNA damage and maintain centrosome stability in colorectal cancer cells. PLoS ONE. 2014;9:e100819 pubmed 出版商
Zhou Y, Caron P, Legube G, Paull T. Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res. 2014;42:e19 pubmed 出版商
Chen Z, Jaafar L, Agyekum D, Xiao H, Wade M, Kumaran R, et al. Receptor-mediated delivery of engineered nucleases for genome modification. Nucleic Acids Res. 2013;41:e182 pubmed 出版商
Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson D, Rai T, et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol. 2013;202:129-43 pubmed 出版商
Starke S, Meinke P, Camozzi D, Mattioli E, Pfaeffle R, Siekmeyer M, et al. Progeroid laminopathy with restrictive dermopathy-like features caused by an isodisomic LMNA mutation p.R435C. Aging (Albany NY). 2013;5:445-59 pubmed
Hsu J, Lin T, Tsai R. Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1. J Cell Biol. 2012;197:613-24 pubmed 出版商
Hewitt G, Jurk D, Marques F, Correia Melo C, Hardy T, Gackowska A, et al. Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Nat Commun. 2012;3:708 pubmed 出版商
Olsen B, Wang S, Svenstrup T, Chen B, Guerra B. Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol. 2012;13:7 pubmed 出版商
Hudson R, Yi M, Esposito D, Watkins S, Hurwitz A, Yfantis H, et al. MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. Nucleic Acids Res. 2012;40:3689-703 pubmed 出版商
Nikitin P, Yan C, Forte E, Bocedi A, Tourigny J, White R, et al. An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell Host Microbe. 2010;8:510-22 pubmed 出版商
Christmann M, Tomicic M, Aasland D, Berdelle N, Kaina B. Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage. Nucleic Acids Res. 2010;38:6418-32 pubmed 出版商
Lee J, Goodarzi A, Jeggo P, Paull T. 53BP1 promotes ATM activity through direct interactions with the MRN complex. EMBO J. 2010;29:574-85 pubmed 出版商
产品信息
SKU号 :
4937S
产品名称 :
53BP1抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, Mk
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
细胞周期/节律点控制
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
450
宿主 :
靶标 :
53BP1
最初蛋白 :
53BP1
别名 :
53BP1,FLJ41424,MGC138366,TP53B,TP53BP1,Tumor suppressor p53-binding protein 1,p202,p53-binding protein 1,p53BP1,tumor protein 53-binding protein, 1,tumor protein p53 binding protein 1,tumor protein p53-binding protein, 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。