产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
NIK抗体
目录 :
4994
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
文章摘录数: 23
出版应用/物种/样品/稀释参考文献
  • 免疫印迹基因敲除验证; 小鼠; 图 s6i
  • 免疫印迹; 小鼠; 图 s6i
Zhao P, Wong K, Sun X, Reilly S, Uhm M, Liao Z, et al. TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue. Cell. 2018;172:731-743.e12 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:500; 图 s3d
  • 免疫印迹; 小鼠; 1:500; 图 4a, s3c
  • 免疫印迹; 人类; 1:500; 图 s3c
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 3d
Fry C, Nayeem S, Dillon E, Sarkar P, Tumurbaatar B, Urban R, et al. Glucocorticoids increase skeletal muscle NF-?B inducing kinase (NIK): links to muscle atrophy. Physiol Rep. 2016;4: pubmed
  • 免疫印迹基因敲除验证; 人类; 图 1
  • 免疫细胞化学; 小鼠; 图 1
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Zhou Y, Xu H, Ding Y, Lu Q, Zou M, Song P. AMPK?1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2. Oncotarget. 2016;7:53654-53667 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹基因敲除验证; 小鼠; 图 s8
Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, et al. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci Rep. 2015;5:17868 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s8
Lin D, Zhang M, Zhang M, Ren Y, Jin J, Zhao Q, et al. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proc Natl Acad Sci U S A. 2015;112:11324-9 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Choi J, Park B, Chi S, Bae K, Kim S, Cho S, et al. HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization. Oncotarget. 2014;5:10084-99 pubmed
  • 免疫印迹; 人类; 图 5d
Baens M, Bonsignore L, Somers R, Vanderheydt C, Weeks S, Gunnarsson J, et al. MALT1 auto-proteolysis is essential for NF-?B-dependent gene transcription in activated lymphocytes. PLoS ONE. 2014;9:e103774 pubmed 出版商
  • 免疫印迹; 人类
Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed 出版商
Vazquez Santillan K, Melendez Zajgla J, Jimenez Hernandez L, Gaytan Cervantes J, Muñoz Galindo L, Pina Sanchez P, et al. NF-kappa?-inducing kinase regulates stem cell phenotype in breast cancer. Sci Rep. 2016;6:37340 pubmed 出版商
Li Y, Zhou Q, Sun W, Chandrasekharan P, Cheng H, Ying Z, et al. Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. Nat Cell Biol. 2015;17:1327-38 pubmed 出版商
Shinzawa M, Konno H, Qin J, Akiyama N, Miyauchi M, Ohashi H, et al. Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression. Sci Rep. 2015;5:10758 pubmed 出版商
Carmona Arana J, Seher A, Neumann M, Lang I, Siegmund D, Wajant H. TNF Receptor-Associated Factor 1 is a Major Target of Soluble TWEAK. Front Immunol. 2014;5:63 pubmed 出版商
Maas C, Tromp J, van Laar J, Thijssen R, Elias J, Malara A, et al. CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex. Cell Death Dis. 2013;4:e782 pubmed 出版商
Rauert Wunderlich H, Siegmund D, Maier E, Giner T, Bargou R, Wajant H, et al. The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NF?B transcription factors. PLoS ONE. 2013;8:e59292 pubmed 出版商
Shih V, Davis Turak J, Macal M, Huang J, Ponomarenko J, Kearns J, et al. Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-?B pathways. Nat Immunol. 2012;13:1162-70 pubmed 出版商
Bakkar N, Ladner K, Canan B, Liyanarachchi S, Bal N, Pant M, et al. IKK? and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism. J Cell Biol. 2012;196:497-511 pubmed 出版商
Rauert H, Stühmer T, Bargou R, Wajant H, Siegmund D. TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms. Cell Death Dis. 2011;2:e194 pubmed 出版商
Li T, Morgan M, Choksi S, Zhang Y, Kim Y, Liu Z. MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. Nat Immunol. 2010;11:799-805 pubmed 出版商
Razani B, Zarnegar B, Ytterberg A, Shiba T, Dempsey P, Ware C, et al. Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation. Sci Signal. 2010;3:ra41 pubmed 出版商
产品信息
SKU号 :
4994P
产品名称 :
NIK抗体
规格 :
40微升
Price-(USD) :
123美元
物种x :
H, M, (R, Mk, B, Hr)
应用 :
免疫沉淀
产品种类 :
免疫学和炎症
运输温度 :
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
125
宿主 :
靶标 :
NIK
最初蛋白 :
Nik
别名 :
FTDCR1B,HS,HsNIK,M3K14,MAP3K14,Mitogen-activated protein kinase kinase kinase 14,NF-kappa-beta-inducing kinase,NIK,Serine/threonine-protein kinase NIK,serine/threonine protein-kinase
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。