产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化4E(Thr37/46)(236B4)兔单克隆抗体(Alexa Fluor系列荧光染料®647共轭标签)
目录 :
5123
克隆性 :
单克隆
宿主 :
共轭标签 :
AF647
抗原修饰 :
磷酸化
克隆名称 :
236B4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 流式细胞仪
文章摘录数: 23
出版应用/物种/样品/稀释参考文献
  • 流式细胞仪; 小鼠; 图 9
Pei B, Zhao M, Miller B, Véla J, Bruinsma M, Virgin H, et al. Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation. J Immunol. 2015;194:5872-84 pubmed 出版商
  • 免疫印迹; 小鼠; 图 f5,f6
Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed 出版商
  • 流式细胞仪; 小鼠
Zhang Y, Wu B, Metelli A, Thaxton J, Hong F, Rachidi S, et al. GP96 is a GARP chaperone and controls regulatory T cell functions. J Clin Invest. 2015;125:859-69 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s7
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed 出版商
Li S, Chen C, Lu H, Huang W, Tien W, Lan Y, et al. Phosphorylated p70S6K expression is an independent prognosticator for patients with esophageal squamous cell carcinoma. Surgery. 2015;157:570-80 pubmed 出版商
Lee H, Park M, Kim M, Kim S, Roh M, Kim K, et al. Overexpression of phosphorylated 4E-binding protein 1 and its clinicopathological significances in gastric cancer. Pathol Res Pract. 2015;211:298-302 pubmed 出版商
Haddad A, Kapur P, Singla N, Raman J, Then M, Nuhn P, et al. Validation of mammalian target of rapamycin biomarker panel in patients with clear cell renal cell carcinoma. Cancer. 2015;121:43-50 pubmed 出版商
Weisberg E, Nonami A, Chen Z, Nelson E, Chen Y, Liu F, et al. Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by small-molecule inhibition of IGF1R. Clin Cancer Res. 2014;20:5483-95 pubmed 出版商
Smith H, Matthews K, Oldham J, Jeanplong F, Falconer S, Bass J, et al. Translational signalling, atrogenic and myogenic gene expression during unloading and reloading of skeletal muscle in myostatin-deficient mice. PLoS ONE. 2014;9:e94356 pubmed 出版商
Fang Z, Lu L, Tian Z, Luo K. Overexpression of phosphorylated 4E-binding protein 1 predicts lymph node metastasis and poor prognosis of Chinese patients with hilar cholangiocarcinoma. Med Oncol. 2014;31:940 pubmed 出版商
Wu J, Shin J, Xie D, Wang H, Gao J, Zhong X. Tuberous sclerosis 1 promotes invariant NKT cell anergy and inhibits invariant NKT cell-mediated antitumor immunity. J Immunol. 2014;192:2643-50 pubmed 出版商
López Rivera E, Jayaraman P, Parikh F, Davies M, Ekmekcioglu S, Izadmehr S, et al. Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2. Cancer Res. 2014;74:1067-78 pubmed 出版商
Rojo F, Domingo L, Sala M, Zazo S, Chamizo C, Menendez S, et al. Gene expression profiling in true interval breast cancer reveals overactivation of the mTOR signaling pathway. Cancer Epidemiol Biomarkers Prev. 2014;23:288-99 pubmed 出版商
Badescu A, Couvelard A, Handra Luca A. Akt pathway protein expression in gastrointestinal Kaposi sarcomas: relevance for tumor biology. APMIS. 2014;122:518-25 pubmed 出版商
Levidou G, Siakantaris M, Papadaki T, Papadavid E, Vassilakopoulos T, Angelopoulou M, et al. A comprehensive immunohistochemical approach of AKT/mTOR pathway and p-STAT3 in mycosis fungoides. J Am Acad Dermatol. 2013;69:375-84 pubmed 出版商
Korkolopoulou P, Levidou G, Trigka E, Prekete N, Karlou M, Thymara I, et al. A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma. BJU Int. 2012;110:E1237-48 pubmed 出版商
Trancikova A, Mamais A, Webber P, Stafa K, Tsika E, Glauser L, et al. Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations. PLoS ONE. 2012;7:e47784 pubmed 出版商
Murai A, Asa S, Kodama A, Hirata A, Yanai T, Sakai H. Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines. BMC Vet Res. 2012;8:128 pubmed 出版商
Murai A, Abou Asa S, Kodama A, Sakai H, Hirata A, Yanai T. Immunohistochemical analysis of the Akt/mTOR/4E-BP1 signalling pathway in canine haemangiomas and haemangiosarcomas. J Comp Pathol. 2012;147:430-40 pubmed 出版商
Yoon D, Ryu M, Park Y, Lee H, Lee C, Ryoo B, et al. Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum. Br J Cancer. 2012;106:1039-44 pubmed 出版商
Xing H, Yang X, Liu T, Lin J, Chen X, Gong Y. The study of resistant mechanisms and reversal in an imatinib resistant Ph+ acute lymphoblastic leukemia cell line. Leuk Res. 2012;36:509-13 pubmed 出版商
Tambe Y, Okuyama N, Nakagawa T, Muramoto A, Hasebe M, Chano T, et al. Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway. Cancer Lett. 2012;314:82-91 pubmed 出版商
Lee D, Do I, Choi K, Sung C, Jang K, Choi D, et al. The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas. Mod Pathol. 2012;25:131-9 pubmed 出版商
产品信息
SKU号 :
5123S
产品名称 :
磷酸化4E(Thr37/46)(236B4)兔单克隆抗体(Alexa Fluor系列荧光染料®647共轭标签)
规格 :
100微升
Price-(USD) :
291美元
物种x :
H, M, R, Mk
应用 :
流式细胞仪
产品种类 :
Translational Control
运输温度 :
储存温度 :
4°C
产品类型 :
单克隆抗体
宿主 :
靶标 :
4E-BP1(Thr37/Thr46)磷酸盐
最初蛋白 :
4E-BP1
别名 :
4E-BP1,4EBP1,BP-1,EIF4EBP1,Eukaryotic translation initiation factor 4E-binding protein 1,MGC4316,PHAS-I,Phosphorylated heat- and acid-stable protein regulated by insulin 1,eIF4E-binding protein 1,eukaryotic translation initiation factor 4E binding protein 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。