产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Cofilin (D3F9) XP® Rabbit mAb
目录 :
5175
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D3F9
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片
文章摘录数: 61
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 6a
Zhang H, Ben Zablah Y, Liu A, Lee D, Zhang H, Meng Y, et al. Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice. Mol Brain. 2021;14:121 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7e
Qiao Y, Jin T, Guan S, Cheng S, Wen S, Zeng H, et al. Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1. Oncogene. 2021;40:4198-4213 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 s3-2b
Renteria R, Cazares C, Baltz E, Schreiner D, Yalcinbas E, Steinkellner T, et al. Mechanism for differential recruitment of orbitostriatal transmission during actions and outcomes following chronic alcohol exposure. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1b
Märklin M, Fuchs A, Tandler C, Heitmann J, Salih H, Kauer J, et al. Genetic Loss of LCK Kinase Leads to Acceleration of Chronic Lymphocytic Leukemia. Front Immunol. 2020;11:1995 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Inda M, Joshi S, Wang T, Bolaender A, Gandu S, Koren Iii J, et al. The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction. Nat Commun. 2020;11:319 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4s2h
Zeng H, Castillo Cabrera J, Manser M, Lu B, Yang Z, Strande V, et al. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:10,000
Sharifnia T, Wawer M, Chen T, Huang Q, Weir B, Sizemore A, et al. Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nat Med. 2019;25:292-300 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5e
Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4j
Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50; 图 5b
Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3g
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed 出版商
  • 流式细胞仪; 人类; 图 4c
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • 免疫印迹; 人类; 1:1000; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 8c
  • 免疫印迹; 小鼠; 1:1000; 图 9a
Kumar A, Paeger L, Kosmas K, Kloppenburg P, Noegel A, Peche V. Neuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2. Front Cell Neurosci. 2016;10:180 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2e
  • 免疫印迹; 人类; 1:700; 图 3c
Gao J, Fu S, Zeng Z, Li F, Niu Q, Jing D, et al. Cyclic stretch promotes osteogenesis-related gene expression in osteoblast-like cells through a cofilin-associated mechanism. Mol Med Rep. 2016;14:218-24 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei F, et al. Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization. Sci Rep. 2016;6:23372 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Liu A, Zhou Z, Dang R, Zhu Y, Qi J, He G, et al. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization. J Cell Biol. 2016;212:449-63 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Lu K, Tounsi A, Shridhar N, Küblbeck G, Klevenz A, Prokosch S, et al. Dickkopf-3 Contributes to the Regulation of Anti-Tumor Immune Responses by Mesenchymal Stem Cells. Front Immunol. 2015;6:645 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Hong N, Qi A, Weaver A. PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biol. 2015;210:753-69 pubmed 出版商
  • 免疫印迹; 人类; 图 s4
Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed 出版商
  • 免疫沉淀; 人类; 图 6
  • 免疫细胞化学; 人类; 图 6
  • 免疫印迹; 人类; 图 6
Dugina V, Khromova N, Rybko V, Blizniukov O, Shagieva G, Chaponnier C, et al. Tumor promotion by γ and suppression by β non-muscle actin isoforms. Oncotarget. 2015;6:14556-71 pubmed
  • 免疫印迹; 小鼠; 图 3a
Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Madak Erdogan Z, Ventrella R, Petry L, Katzenellenbogen B. Novel roles for ERK5 and cofilin as critical mediators linking ER?-driven transcription, actin reorganization, and invasiveness in breast cancer. Mol Cancer Res. 2014;12:714-27 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400
  • 免疫细胞化学; 人类; 1:1000; 图 4
  • 免疫印迹; 人类; 1:1000
Polachini G, Sobral L, Mercante A, Paes Leme A, Xavier F, Henrique T, et al. Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis. PLoS ONE. 2012;7:e50517 pubmed 出版商
Zhang L, Wang L, Hiremath U, Bisoyi H, Nair G, Yelamaggad C, et al. Dynamic Orthogonal Switching of a Thermoresponsive Self-Organized Helical Superstructure. Adv Mater. 2017;29: pubmed 出版商
Valderrama C, Clark A, Urano F, Unanue E, Carrero J. Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice. Eur J Immunol. 2017;47:830-840 pubmed 出版商
Ang W, Church A, Kulis M, Choi H, Burks A, Abraham S. Mast cell desensitization inhibits calcium flux and aberrantly remodels actin. J Clin Invest. 2016;126:4103-4118 pubmed 出版商
Sengelaub C, Navrazhina K, Ross J, Halberg N, Tavazoie S. PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling. EMBO J. 2016;35:62-76 pubmed 出版商
Tominaga N, Kosaka N, Ono M, Katsuda T, Yoshioka Y, Tamura K, et al. Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat Commun. 2015;6:6716 pubmed 出版商
Speranza L, Giuliano T, Volpicelli F, De Stefano M, Lombardi L, Chambery A, et al. Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics. Front Behav Neurosci. 2015;9:62 pubmed 出版商
Li C, Lun W, Zhao X, Lei S, Guo Y, Ma J, et al. Allicin alleviates inflammation of trinitrobenzenesulfonic acid-induced rats and suppresses P38 and JNK pathways in Caco-2 cells. Mediators Inflamm. 2015;2015:434692 pubmed 出版商
Garcia Manero G, Khoury H, Jabbour E, Lancet J, Winski S, Cable L, et al. A phase I study of oral ARRY-614, a p38 MAPK/Tie2 dual inhibitor, in patients with low or intermediate-1 risk myelodysplastic syndromes. Clin Cancer Res. 2015;21:985-94 pubmed 出版商
Gaumann A, Drexler H, Lang S, Stoeltzing O, Diermeier Daucher S, Buchdunger E, et al. The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®). Int J Oncol. 2014;45:2267-77 pubmed 出版商
Liu J, Lin X, Yang X, Zhou L, He S, Zhuang S, et al. A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells. Nucleic Acids Res. 2014;42:12041-51 pubmed 出版商
Martínez Neri P, López Rincón G, Mancilla Jiménez R, Del Toro Arreola S, Muñoz Valle J, Fafutis Morris M, et al. Prolactin modulates cytokine production induced by culture filtrate proteins of M. bovis through different signaling mechanisms in THP1 cells. Cytokine. 2015;71:38-44 pubmed 出版商
Yu G, Lee Y, Cheng C, Wu C, Song J, Gallick G, et al. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res. 2015;13:348-57 pubmed 出版商
Bielig H, Lautz K, Braun P, Menning M, Machuy N, Brügmann C, et al. The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling. PLoS Pathog. 2014;10:e1004351 pubmed 出版商
Jacob S, Foster A, Yemelin A, Thines E. Histidine kinases mediate differentiation, stress response, and pathogenicity in Magnaporthe oryzae. Microbiologyopen. 2014;3:668-87 pubmed 出版商
Crocetti J, Silva O, Humphries L, Tibbs M, Miceli M. Selective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells. J Immunol. 2014;193:2651-60 pubmed 出版商
Kimura T, Kobayashi S, Hanihara Tatsuzawa F, Sayama A, Maruyama T, Muta T. Responses of macrophages to the danger signals released from necrotic cells. Int Immunol. 2014;26:697-704 pubmed 出版商
Birner P, Berghoff A, Dinhof C, Pirker C, Capper D, Schoppmann S, et al. MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases. Arch Dermatol Res. 2014;306:873-84 pubmed 出版商
Wang C, Li G, Shi Y, Zhang X, Li J, Wang Z, et al. Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons. J Physiol Biochem. 2014;70:735-47 pubmed 出版商
Kumawat K, Menzen M, Slegtenhorst R, Halayko A, Schmidt M, Gosens R. TGF-?-activated kinase 1 (TAK1) signaling regulates TGF-?-induced WNT-5A expression in airway smooth muscle cells via Sp1 and ?-catenin. PLoS ONE. 2014;9:e94801 pubmed 出版商
Wang C, Zhang L, Li G, Shi Y, Li J, Zhang X, et al. Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion. J Neurosci Res. 2014;92:944-54 pubmed 出版商
Cai W, Liang L, Wang L, Han J, Zhu X, Han H, et al. Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs. Cell Immunol. 2014;287:129-35 pubmed 出版商
Wang C, Li J, Zhang L, Zhang X, Yu S, Liang X, et al. Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-?B signal pathway. Neurochem Int. 2013;63:741-9 pubmed 出版商
Nomura J, Busso N, Ives A, Tsujimoto S, Tamura M, So A, et al. Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK. PLoS ONE. 2013;8:e75527 pubmed 出版商
Liu G, Bi Y, Wang R, Shen B, Zhang Y, Yang H, et al. Kinase AKT1 negatively controls neutrophil recruitment and function in mice. J Immunol. 2013;191:2680-90 pubmed 出版商
Feige E, Yacov N, Salem Y, Levi I, Mendel I, Propheta Meiran O, et al. Inhibition of monocyte chemotaxis by VB-201, a small molecule lecinoxoid, hinders atherosclerosis development in ApoE?/? mice. Atherosclerosis. 2013;229:430-9 pubmed 出版商
Ammann J, Cooke A, Trowsdale J. Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol. 2013;190:5030-6 pubmed 出版商
Aguilera Montilla N, Chamorro S, Nieto C, Sanchez Cabo F, Dopazo A, Fernández Salguero P, et al. Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells. Blood. 2013;121:e108-17 pubmed 出版商
Cochonneau D, Terme M, Michaud A, Dorvillius M, Gautier N, Frikeche J, et al. Cell cycle arrest and apoptosis induced by O-acetyl-GD2-specific monoclonal antibody 8B6 inhibits tumor growth in vitro and in vivo. Cancer Lett. 2013;333:194-204 pubmed 出版商
Yamada J, Jinno S. Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis. J Comp Neurol. 2013;521:1184-201 pubmed 出版商
Stavniichuk R, Shevalye H, Hirooka H, Nadler J, Obrosova I. Interplay of sorbitol pathway of glucose metabolism, 12/15-lipoxygenase, and mitogen-activated protein kinases in the pathogenesis of diabetic peripheral neuropathy. Biochem Pharmacol. 2012;83:932-40 pubmed 出版商
Kogai T, Liu Y, Mody K, Shamsian D, Brent G. Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012;287:3292-300 pubmed 出版商
产品信息
SKU号 :
5175S
产品名称 :
Cofilin (D3F9) XP® Rabbit mAb
规格 :
100微升
Price-(USD) :
260美元
物种x :
H, M, R, Mk, Dg
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
Cytoskeletal Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
19
宿主 :
靶标 :
cofilin 1
最初蛋白 :
cofilin 1
别名 :
18 kDa phosphoprotein,CFL,CFL1,COF1,Cofilin, non-muscle isoform,Cofilin-1,cofilin 1 (non-muscle),p18
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。