产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Acetyl-α-Tubulin (Lys40) (D20G3) XP® Rabbit mAb
目录 :
5335
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D20G3
反应物种 :
人类, 小鼠, 大鼠, pigs , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray
文章摘录数: 51
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; pigs ; 图 4i
Wang Z, Chen J, Wu X, Ma D, Zhang X, Li R, et al. PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection. PLoS Pathog. 2021;17:e1009940 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:1000; 图 3a
Łysyganicz P, Pooranachandran N, Liu X, Adamson K, Zielonka K, Elworthy S, et al. Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia. Front Cell Dev Biol. 2021;9:676214 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5a
  • 免疫印迹; 人类; 图 2a
Ko P, Choi J, Song S, Keum S, Jeong J, Hwang Y, et al. Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1f
Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Shen Z, Ji K, Cai Z, Huang C, He X, Xu H, et al. Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy. Aging (Albany NY). 2021;13:9820-9837 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Siegel D, Bersie S, Harris P, Di Francesco A, Armstrong M, Reisdorph N, et al. A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation. Redox Biol. 2021;39:101840 pubmed 出版商
  • 免疫细胞化学; 人类; 1:10,000; 图 s1e
Ha K, Nobuhara M, Wang Q, Walker R, Qian F, Schartner C, et al. The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3h
Lian B, Pei Y, Jiang Y, Xue M, Li D, Li X, et al. Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer. Theranostics. 2020;10:11092-11109 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 5a
Van Bergen N, Ahmed S, Collins F, Cowley M, Vetro A, Dale R, et al. Mutations in the exocyst component EXOC2 cause severe defects in human brain development. J Exp Med. 2020;217: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4a
Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5b
Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:800; 图 1f
Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 e5d
Eckert M, Coscia F, Chryplewicz A, Chang J, Hernandez K, Pan S, et al. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019;: pubmed 出版商
  • 免疫细胞化学; pigs ; 1:1000; 图 6e
Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
  • 免疫印迹; 人类; 图 4a
Tan H, Liao H, Zhao L, Lu Y, Jiang S, Tao D, et al. HILI destabilizes microtubules by suppressing phosphorylation and Gigaxonin-mediated degradation of TBCB. Sci Rep. 2017;7:46376 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:800; 图 4b
Benbow S, Wozniak K, Kulesh B, Savage A, Slusher B, Littlefield B, et al. Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2017;32:151-162 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5i
McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 3a
Funabashi T, Katoh Y, Michisaka S, Terada M, Sugawa M, Nakayama K. Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol Biol Cell. 2017;28:624-633 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:800; 图 7a
  • 免疫细胞化学; 人类; 1:800; 图 s2
Yu F, Sharma S, Skowronek A, Erdmann K. The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis. Sci Rep. 2016;6:35399 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 6c
Medler T, Craig J, Fiorillo A, Feeney Y, Harrell J, Clevenger C. HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth. Mol Cancer Res. 2016;14:994-1008 pubmed
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 2
Skoge R, Ziegler M. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. J Cell Sci. 2016;129:2972-82 pubmed 出版商
  • 免疫组化; 小鼠; 图 2
Airik R, Schueler M, Airik M, Cho J, Ulanowicz K, Porath J, et al. SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling. PLoS ONE. 2016;11:e0156081 pubmed 出版商
  • 免疫组化; 小鼠; 1:800; 图 4d
Benbow S, Cook B, Reifert J, Wozniak K, Slusher B, Littlefield B, et al. Effects of Paclitaxel and Eribulin in Mouse Sciatic Nerve: A Microtubule-Based Rationale for the Differential Induction of Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2016;29:299-313 pubmed 出版商
  • 免疫细胞化学; 人类; 1:800; 图 4
  • 免疫印迹; 人类; 图 4
Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Jovasevic V, Naghavi M, Walsh D. Microtubule plus end-associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells. J Cell Biol. 2015;211:323-37 pubmed 出版商
  • 免疫细胞化学; 小鼠
Brown J, Santra T, Owens P, Morrison A, Barry F. Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia. Stem Cell Res. 2014;13:284-99 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1-s3
Wang W, Wu T, Kirschner M. The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium. elife. 2014;3:e03083 pubmed 出版商
  • 免疫组化; pigs ; 1:800
Hou L, Ma F, Yang J, Riaz H, Wang Y, Wu W, et al. Effects of histone deacetylase inhibitor oxamflatin on in vitro porcine somatic cell nuclear transfer embryos. Cell Reprogram. 2014;16:253-65 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Balmer N, Klima S, Rempel E, Ivanova V, Kolde R, Weng M, et al. From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014;88:1451-68 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500
Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1200; 图 1
Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L. Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion. J Cell Sci. 2014;127:1631-9 pubmed 出版商
Choi H, Madhu V, Shapiro I, Risbud M. Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation. Sci Rep. 2019;9:15469 pubmed 出版商
Gilmore Hall S, Kuo J, Ward J, Zahra R, Morrison R, Perkins G, et al. CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. J Cell Biol. 2019;218:206-219 pubmed 出版商
Arango D, Sturgill D, Alhusaini N, Dillman A, Sweet T, Hanson G, et al. Acetylation of Cytidine in mRNA Promotes Translation Efficiency. Cell. 2018;175:1872-1886.e24 pubmed 出版商
Cooney A, Singh B, Loza L, Thornell I, Hippee C, Powers L, et al. Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus. Nucleic Acids Res. 2018;46:9591-9600 pubmed 出版商
Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, et al. The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. PLoS Biol. 2018;16:e2005651 pubmed 出版商
Li F, Sawada J, Komatsu M. R-Ras-Akt axis induces endothelial lumenogenesis and regulates the patency of regenerating vasculature. Nat Commun. 2017;8:1720 pubmed 出版商
Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed 出版商
Adler C, SANCHEZ ALVARADO A. PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration. Dev Biol. 2017;427:165-175 pubmed 出版商
Loukil A, Tormanen K, Sütterlin C. The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome. J Cell Biol. 2017;216:1287-1300 pubmed 出版商
Badgandi H, Hwang S, Shimada I, Loriot E, Mukhopadhyay S. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. J Cell Biol. 2017;216:743-760 pubmed 出版商
Sundriyal S, Moniot S, Mahmud Z, YAO S, Di Fruscia P, Reynolds C, et al. Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket. J Med Chem. 2017;60:1928-1945 pubmed 出版商
Xavier A, Ludwig R, Nagai M, de Almeida T, Watanabe H, Hirata M, et al. CD36 is expressed in a defined subpopulation of neurons in the olfactory epithelium. Sci Rep. 2016;6:25507 pubmed 出版商
Yan Y, Tan K, Li C, Tran T, Chao S, Sugrue R, et al. Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza virus infection in vitro. J Allergy Clin Immunol. 2016;138:276-281.e15 pubmed 出版商
Taylor S, Dantas T, Durán I, Wu S, Lachman R, Nelson S, et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. Nat Commun. 2015;6:7092 pubmed 出版商
Boggs A, Vitolo M, Whipple R, Charpentier M, Goloubeva O, Ioffe O, et al. ?-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration. Cancer Res. 2015;75:203-15 pubmed 出版商
Steg A, Burke M, Amm H, Katre A, Dobbin Z, Jeong D, et al. Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer. Oncotarget. 2014;5:7065-80 pubmed
Skoge R, Dölle C, Ziegler M. Regulation of SIRT2-dependent ?-tubulin deacetylation by cellular NAD levels. DNA Repair (Amst). 2014;23:33-8 pubmed 出版商
产品信息
SKU号 :
5335P
产品名称 :
Acetyl-α-Tubulin (Lys40) (D20G3) XP® Rabbit mAb
规格 :
40微升
Price-(USD) :
135美元
物种x :
H, M, R, Mk, Z
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
Cytoskeletal Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
52
宿主 :
靶标 :
微管蛋白甲(Lys40)乙酰化
最初蛋白 :
TUBA1B
别名 :
Alpha-tubulin ubiquitous,K-ALPHA-1,TBA1B,TUBA1B,Tubulin K-alpha-1,Tubulin alpha-1B chain,Tubulin alpha-ubiquitous chain,alpha tubulin,tubulin, alpha 1b,tubulin, alpha, ubiquitous
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。