产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
HDAC1(10E2)小鼠单克隆抗体
目录 :
5356
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
10E2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-冰冻切片, 核糖核酸免疫沉淀
文章摘录数: 49
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 s6b
Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed 出版商
  • 免疫印迹; 人类; 图 1g
Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商
  • 免疫印迹; 人类; 图 s6c
Alam M, Gaida M, Debnath S, Tagad H, Miller Jenkins L, Appella E, et al. Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation. PLoS Biol. 2018;16:e2004111 pubmed 出版商
  • 免疫沉淀; 人类; 图 3a
  • 免疫印迹; 人类; 图 1b
Tikhanovich I, Zhao J, Bridges B, Kumer S, Roberts B, Weinman S. Arginine methylation regulates c-Myc-dependent transcription by altering promoter recruitment of the acetyltransferase p300. J Biol Chem. 2017;292:13333-13344 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7c
Yi J, Paranjape S, Walker M, Choudhury R, Wolter J, Fragola G, et al. The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/?-catenin pathway by inhibiting the proteasome. J Biol Chem. 2017;292:12503-12515 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 7b
Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠; 图 2d
  • 免疫组化; 大鼠; 1:200; 图 2c
  • 免疫印迹; 大鼠; 1:1000; 图 2a
Tao C, Hsu W, Ma Y, Cheng S, Lee E. Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2017;24:597-614 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4a
Gilbert J, Man H. The X-Linked Autism Protein KIAA2022/KIDLIA Regulates Neurite Outgrowth via N-Cadherin and ?-Catenin Signaling. Eneuro. 2016;3: pubmed
  • 免疫印迹; 人类; 图 5d
Bao M, Wang Y, Liu Y, Shi P, Lu H, Sha W, et al. NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells. J Exp Med. 2016;213:2383-2398 pubmed
  • 免疫沉淀; 人类; 图 5a
  • 免疫印迹; 人类; 图 2b
Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
  • 免疫印迹; 人类; 图 1b
Ramakrishnan S, Ku S, Ciamporcero E, Miles K, Attwood K, Chintala S, et al. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma. BMC Cancer. 2016;16:617 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Gay G, Braun L, Brenier Pinchart M, Vollaire J, Josserand V, Bertini R, et al. Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-?-mediated host defenses. J Exp Med. 2016;213:1779-98 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5e,7b
Grinshtein N, Rioseco C, Marcellus R, UEHLING D, Aman A, Lun X, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. 2016;7:59360-59376 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6d
Yard B, Adams D, Chie E, Tamayo P, Battaglia J, Gopal P, et al. A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nat Commun. 2016;7:11428 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1b
Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed 出版商
  • 核糖核酸免疫沉淀; 人类; 图 3
  • 免疫印迹; 人类; 图 s3
G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Paladino D, Yue P, Furuya H, Acoba J, Rosser C, Turkson J. A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget. 2016;7:7253-67 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 6
Akhade V, Dighe S, Kataruka S, Rao M. Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells. Nucleic Acids Res. 2016;44:387-401 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 3
Vishwakarma B, Nguyen N, Makishima H, Hosono N, Gudmundsson K, Negi V, et al. Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development. Leukemia. 2016;30:200-8 pubmed 出版商
  • 免疫印迹; 人类
Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5
Eisses J, Criscimanna A, Dionise Z, Orabi A, Javed T, Sarwar S, et al. Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. Am J Pathol. 2015;185:3304-15 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Pickard A, McDade S, McFarland M, McCluggage W, Wheeler C, McCance D. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures. PLoS Pathog. 2015;11:e1004988 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠; 图  6
  • 免疫印迹; 大鼠; 1:1000; 图 8
Formisano L, Guida N, Valsecchi V, Cantile M, Cuomo O, Vinciguerra A, et al. Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism. J Neurosci. 2015;35:7332-48 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Watanabe M, Takahashi H, Saeki Y, Ozaki T, Itoh S, Suzuki M, et al. The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ. elife. 2015;4:e05615 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5c
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed 出版商
  • 免疫印迹; 大鼠
Blakeslee W, Wysoczynski C, Fritz K, Nyborg J, Churchill M, McKinsey T. Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism. Cell Signal. 2014;26:2912-20 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Bots M, Verbrugge I, Martin B, Salmon J, Ghisi M, Baker A, et al. Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. 2014;123:1341-52 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed 出版商
Wobser M, Weber A, Glunz A, Tauch S, Seitz K, Butelmann T, et al. Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells. J Hematol Oncol. 2019;12:30 pubmed 出版商
Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed 出版商
Rajarajacholan U, Thalappilly S, Riabowol K. ING1 regulates rRNA levels by altering nucleolar chromatin structure and mTOR localization. Nucleic Acids Res. 2017;45:1776-1792 pubmed 出版商
Witt A, Lee C, Lee T, Azzam D, Wang B, Caslini C, et al. Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer. Oncogene. 2017;36:1707-1720 pubmed 出版商
Deng Z, Liu X, Jin J, Xu H, Gao Q, Wang Y, et al. Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation. Int J Biol Sci. 2016;12:1298-1308 pubmed
Khalil H, Langdon S, Goltsov A, Soininen T, Harrison D, Bown J, et al. A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells. Oncotarget. 2016;7:75874-75901 pubmed 出版商
Shi G, Yoshida Y, Yuki K, Nishimura T, Kawata Y, Kawashima M, et al. Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity. Oncotarget. 2016;7:82158-82169 pubmed 出版商
Subburaju S, Coleman A, Ruzicka W, Benes F. Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model. Transl Psychiatry. 2016;6:e723 pubmed 出版商
Wu Q, Nie J, Gao Y, Xu P, Sun Q, Yang J, et al. Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1. Sci Rep. 2015;5:16355 pubmed 出版商
Grasso C, Tang Y, Truffaux N, Berlow N, Liu L, Debily M, et al. Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nat Med. 2015;21:555-9 pubmed 出版商
Li L, Xue A, Li B, Shen Y, Li Y, Luo C, et al. JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI. Breast Cancer Res. 2014;16:R56 pubmed 出版商
Wang X, Wang C, Wang J, Zhao S, Zhang K, Wang J, et al. Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-?B, MAPKs and Akt signaling pathways. Neuropharmacology. 2014;79:642-56 pubmed 出版商
Potluri V, Noothi S, Vallabhapurapu S, Yoon S, Driscoll J, Lawrie C, et al. Transcriptional repression of Bim by a novel YY1-RelA complex is essential for the survival and growth of Multiple Myeloma. PLoS ONE. 2013;8:e66121 pubmed 出版商
Cox E, Marsh S. Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart. Cardiovasc Diabetol. 2013;12:101 pubmed 出版商
Cai Y, Cui W, Chen W, Wei P, Chi Y, Zhang P, et al. The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms. Cancer Cell Int. 2013;13:57 pubmed 出版商
Nicholson T, Singh A, Su H, Hevi S, Wang J, Bajko J, et al. A hypomorphic lsd1 allele results in heart development defects in mice. PLoS ONE. 2013;8:e60913 pubmed 出版商
Li M, Riddle S, Frid M, El Kasmi K, McKinsey T, Sokol R, et al. Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol. 2011;187:2711-22 pubmed 出版商
产品信息
SKU号 :
5356S
产品名称 :
HDAC1(10E2)小鼠单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, Mk
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
Chromatin Regulation / Nuclear Function
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
62
宿主 :
小鼠
靶标 :
HDAC1
最初蛋白 :
HDAC1
别名 :
DKFZp686H12203,GON-10,HD1,HDAC1,Histone deacetylase 1,RPD3,RPD3L1,reduced potassium dependency, yeast homolog-like 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。