Published Application/Species/Dilution | Reference |
- western blot; human; 1:1000; fig 9
| E L, Swerdlow R. Lactate's effect on human neuroblastoma cell bioenergetic fluxes. Biochem Pharmacol. 2016;99:88-100 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:1000
| Selfridge J, Wilkins H, E L, Carl S, Koppel S, Funk E, et al. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. J Bioenerg Biomembr. 2015;47:1-11 pubmed publisher
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- western blot; mouse; 1:1000
| E L, Burns J, Swerdlow R. Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. Neurobiol Aging. 2014;35:2574-83 pubmed publisher
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| Kuboki Y, Shimizu K, Hatori T, Yamamoto M, Shibata N, Shiratori K, et al. Molecular biomarkers for progression of intraductal papillary mucinous neoplasm of the pancreas. Pancreas. 2015;44:227-35 pubmed publisher
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| Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, et al. A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib. Biochem Pharmacol. 2015;95:16-27 pubmed publisher
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| Rohrbach T, Jarboe J, Anderson J, Trummell H, Hicks P, Weaver A, et al. Targeting the effector domain of the myristoylated alanine rich C-kinase substrate enhances lung cancer radiation sensitivity. Int J Oncol. 2015;46:1079-88 pubmed publisher
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| Nakakido M, Deng Z, Suzuki T, Dohmae N, Nakamura Y, Hamamoto R. Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. Neoplasia. 2015;17:367-73 pubmed publisher
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| Moriya J, Ferrara N. Inhibition of protein kinase C enhances angiogenesis induced by platelet-derived growth factor C in hyperglycemic endothelial cells. Cardiovasc Diabetol. 2015;14:180 pubmed publisher
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| Algars A, Avoranta T, Osterlund P, Lintunen M, Sundström J, Jokilehto T, et al. Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy. PLoS ONE. 2014;9:e99590 pubmed publisher
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| Takagi S, Takemoto A, Takami M, Oh-hara T, Fujita N. Platelets promote osteosarcoma cell growth through activation of the platelet-derived growth factor receptor-Akt signaling axis. Cancer Sci. 2014;105:983-8 pubmed publisher
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| Luo J, Weaver M, Cao B, Dennis J, Van Biber B, Laflamme M, et al. Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo. Stem Cells Transl Med. 2014;3:734-44 pubmed publisher
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| Bao M, Zhang Y, Lou X, Xiao Y, Cheng Y, Zhou H. Puerarin protects endothelial cells from oxidized low density lipoprotein induced injuries via the suppression of LOX-1 and induction of eNOS. Can J Physiol Pharmacol. 2014;92:299-306 pubmed publisher
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| Medina E, Oberheu K, Polusani S, Ortega V, Velagaleti G, Oyajobi B. PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells. Leukemia. 2014;28:2080-9 pubmed publisher
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| Liu J, Ke F, Xu Z, Liu Z, Zhang L, Yan S, et al. CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo. PLoS ONE. 2014;9:e101137 pubmed publisher
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| Schmid C, Streicher J, Meltzer H, Bohn L. Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt. Neuropsychopharmacology. 2014;39:1902-13 pubmed publisher
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| Shimabukuro J, Yamaoka A, Murata K, Kotani E, Hirano T, Nakajima Y, et al. 3D co-cultures of keratinocytes and melanocytes and cytoprotective effects on keratinocytes against reactive oxygen species by insect virus-derived protein microcrystals. Mater Sci Eng C Mater Biol Appl. 2014;42:64-9 pubmed publisher
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| Kim H, Abd Elmageed Z, Davis C, El-Bahrawy A, Naura A, Ekaidi I, et al. Correlation between PDZK1, Cdc37, Akt and breast cancer malignancy: the role of PDZK1 in cell growth through Akt stabilization by increasing and interacting with Cdc37. Mol Med. 2014;20:270-9 pubmed publisher
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| Xiao W, Feng Y, Holst J, Hartmann B, Yang H, Teitelbaum D. Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition. FASEB J. 2014;28:2073-87 pubmed publisher
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| el-Gazzar A, Cai X, Reeves R, Dai Z, Caballero-Benítez A, McDonald D, et al. Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells. Oncogene. 2014;33:4932-40 pubmed publisher
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| Miura H, Matsuda M, Aoki K. Development of a FRET biosensor with high specificity for Akt. Cell Struct Funct. 2014;39:9-20 pubmed
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| Zhang X, Yang B, Wang J, Mo X, Zhang J, Hua Z. FADD is essential for glucose uptake and survival of thymocytes. Biochem Biophys Res Commun. 2014;451:202-7 pubmed publisher
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| Hauser J, Lindner R. Coalescence of B cell receptor and invariant chain MHC II in a raft-like membrane domain. J Leukoc Biol. 2014;96:843-55 pubmed publisher
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| Trucco L, Andreoli V, Núñez N, Maccioni M, Bocco J. Krüppel-like factor 6 interferes with cellular transformation induced by the H-ras oncogene. FASEB J. 2014;28:5262-76 pubmed publisher
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| Gronnier C, Bruyère E, Lahdaoui F, Jonckheere N, Perrais M, Leteurtre E, et al. The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells. Biochim Biophys Acta. 2014;1843:2432-7 pubmed publisher
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| Cheng X, Li Y, Tan J, Sun B, Xiao Y, Fang X, et al. CCL20 and CXCL8 synergize to promote progression and poor survival outcome in patients with colorectal cancer by collaborative induction of the epithelial-mesenchymal transition. Cancer Lett. 2014;348:77-87 pubmed publisher
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| Katayama R, Friboulet L, Koike S, Lockerman E, Khan T, Gainor J, et al. Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib. Clin Cancer Res. 2014;20:5686-96 pubmed publisher
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| Aoyama A, Katayama R, Oh-hara T, Sato S, Okuno Y, Fujita N. Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter-mediated drug resistance. Mol Cancer Ther. 2014;13:2978-90 pubmed publisher
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| Ghosh A, Lu G, Su G, McEvoy B, Sadiq O, DiMusto P, et al. Phosphorylation of AKT and abdominal aortic aneurysm formation. Am J Pathol. 2014;184:148-58 pubmed publisher
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| Fuke Y, Hishinuma M, Namikawa M, Oishi Y, Matsuzaki T. Wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human breast cancer by possible involvement of the NF-κB pathways. Nutr Cancer. 2014;66:879-87 pubmed publisher
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| Tang H, Zhang Q, Yang L, Dong Y, Khan M, Yang F, et al. Reprint of "GPR30 mediates estrogen rapid signaling and neuroprotection". Mol Cell Endocrinol. 2014;389:92-8 pubmed publisher
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| Bao M, Zhang Y, Lou X, Cheng Y, Zhou H. Protective effects of let-7a and let-7b on oxidized low-density lipoprotein induced endothelial cell injuries. PLoS ONE. 2014;9:e106540 pubmed publisher
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| Wang Q, Wang H, Zhang Y, Zhang Y, Xiao W. Activation of uPAR is required for cigarette smoke extract-induced epithelial-mesenchymal transition in lung epithelial cells. Oncol Res. 2013;21:295-305 pubmed publisher
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| Lorenzato A, Biolatti M, Delogu G, Capobianco G, Farace C, Dessole S, et al. AKT activation drives the nuclear localization of CSE1L and a pro-oncogenic transcriptional activation in ovarian cancer cells. Exp Cell Res. 2013;319:2627-36 pubmed publisher
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| Fujiki K, Inamura H, Matsuoka M. Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium. Arch Toxicol. 2013;87:2119-27 pubmed publisher
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| Sadighi Akha A, Theriot C, Erb-Downward J, McDermott A, Falkowski N, Tyra H, et al. Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology. 2013;140:111-22 pubmed publisher
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| de Jong A, Maass A, Oberdorf-Maass S, de Boer R, van Gilst W, Van Gelder I. Cyclical stretch induces structural changes in atrial myocytes. J Cell Mol Med. 2013;17:743-53 pubmed publisher
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| Wu A, Dalvi P, Lu X, Yang M, Riddick D, Matthews J, et al. Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells. Mol Pharmacol. 2013;83:377-88 pubmed publisher
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| Kota V, Dhople V, Fullbright G, Smythe N, Szulc Z, Bielawska A, et al. 2'-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells. J Proteome Res. 2013;12:4366-75 pubmed publisher
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| Benhenda S, Ducroux A, Rivière L, Sobhian B, Ward M, Dion S, et al. Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol. 2013;87:4360-71 pubmed publisher
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| Goyal P, Brünnert D, Ehrhardt J, Bredow M, Piccenini S, Zygmunt M. Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways. Mol Hum Reprod. 2013;19:528-38 pubmed publisher
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| Guo F, Ma Y, Kadegowda A, Betters J, Xie P, Liu G, et al. Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice. J Lipid Res. 2013;54:2109-20 pubmed publisher
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| Liao R, Jung J, Tchaicha J, Wilkerson M, Sivachenko A, Beauchamp E, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013;73:5195-205 pubmed publisher
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| Nakles R, Kallakury B, Furth P. The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. Am J Pathol. 2013;182:1976-85 pubmed publisher
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| Mukhopadhyay C, Zhao X, Maroni D, Band V, Naramura M. Distinct effects of EGFR ligands on human mammary epithelial cell differentiation. PLoS ONE. 2013;8:e75907 pubmed publisher
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| Kharbanda A, Rajabi H, Jin C, Raina D, Kufe D. Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer. Mol Cancer Res. 2013;11:714-23 pubmed publisher
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| Cheng L, Lin Z, Shu R, Liu D, Zhang X, Liu B, et al. Analogous effects of recombinant human full-length amelogenin expressed by Pichia pastoris yeast and enamel matrix derivative in vitro. Cell Prolif. 2012;45:456-65 pubmed publisher
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| Tsujimoto I, Yoshida A, Yoneda-Kato N, Kato J. Depletion of CSN5 inhibits Ras-mediated tumorigenesis by inducing premature senescence in p53-null cells. FEBS Lett. 2012;586:4326-31 pubmed publisher
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| Fujita M, Tohji C, Honda Y, Yamamoto Y, Nakamura T, Yagami T, et al. Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. Int J Med Sci. 2012;9:555-66 pubmed
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| Jonckheere N, Skrypek N, Merlin J, Dessein A, Dumont P, Leteurtre E, et al. The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways. PLoS ONE. 2012;7:e32232 pubmed publisher
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| Sharma N, Kumar V, Everingham S, Mali R, Kapur R, Zeng L, et al. SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice. Mol Cell Biol. 2012;32:2653-63 pubmed publisher
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| Almansour N, Pirogova E, Coloe P, Cosic I, Istivan T. A bioactive peptide analogue for myxoma virus protein with a targeted cytotoxicity for human skin cancer in vitro. J Biomed Sci. 2012;19:65 pubmed publisher
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| Cervelli V, Scioli M, Gentile P, Doldo E, Bonanno E, Spagnoli L, et al. Platelet-rich plasma greatly potentiates insulin-induced adipogenic differentiation of human adipose-derived stem cells through a serine/threonine kinase Akt-dependent mechanism and promotes clinical fat graft maintenance. Stem Cells Transl Med. 2012;1:206-20 pubmed publisher
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| Tsunoda T, Ota T, Fujimoto T, Doi K, Tanaka Y, Yoshida Y, et al. Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model. Mol Cancer. 2012;11:46 pubmed publisher
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| Wen Q, Zhou L, Zhou C, Zhou M, Luo W, Ma L. Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration. J Cell Mol Med. 2012;16:1260-73 pubmed publisher
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| Asai J, Takenaka H, Hirakawa S, Sakabe J, Hagura A, Kishimoto S, et al. Topical simvastatin accelerates wound healing in diabetes by enhancing angiogenesis and lymphangiogenesis. Am J Pathol. 2012;181:2217-24 pubmed publisher
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| Zhang S, Zhou X, Lang R, Guo F. RhoA of the Rho family small GTPases is essential for B lymphocyte development. PLoS ONE. 2012;7:e33773 pubmed publisher
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| Zhao Q, Niu Y, Matsumoto K, Tsuneyama K, Tanaka K, Miyata T, et al. Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain. BMC Complement Altern Med. 2012;12:188 pubmed publisher
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| Mundra J, Terskiy A, Howells R. Naltrindole inhibits human multiple myeloma cell proliferation in vitro and in a murine xenograft model in vivo. J Pharmacol Exp Ther. 2012;342:273-87 pubmed publisher
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