产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb
目录 :
5621
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D7A11
反应物种 :
malaria parasite P. falciparum, 人类, 小鼠, 大鼠, fruit fly
应用 :
免疫印迹, 免疫沉淀
文章摘录数: 46
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 3h
Ji M, Zhao Z, Li Y, Xu P, Shi J, Li Z, et al. FBXO6-mediated RNASET2 ubiquitination and degradation governs the development of ovarian cancer. Cell Death Dis. 2021;12:317 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Guo S, Chen Y, Yang Y, Zhang X, Ma L, Xue X, et al. TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stress. Cell Death Dis. 2021;12:42 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6f
Wang W, Hu D, Wu C, Feng Y, Li A, Liu W, et al. STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection. PLoS Pathog. 2020;16:e1008335 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Gain C, Malik S, Bhattacharjee S, Ghosh A, Robertson E, Das B, et al. Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway. PLoS Pathog. 2020;16:e1008105 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
  • 免疫印迹; 人类; 图 5f
Chen M, Zhao Z, Meng Q, Liang P, Su Z, Wu Y, et al. TRIM14 Promotes Noncanonical NF-κB Activation by Modulating p100/p52 Stability via Selective Autophagy. Adv Sci (Weinh). 2020;7:1901261 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s6c
Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Luo H, Jing B, Xia Y, Zhang Y, Hu M, Cai H, et al. WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia. Cancer Cell Int. 2019;19:56 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed 出版商
  • 免疫沉淀; 小鼠; 1:1000; 图 5c
Panda S, Gekara N. The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. Nat Commun. 2018;9:4654 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3g
Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 6e
Yang L, Wang L, Ketkar H, Ma J, Yang G, Cui S, et al. UBXN3B positively regulates STING-mediated antiviral immune responses. Nat Commun. 2018;9:2329 pubmed 出版商
  • 免疫印迹; 人类; 图 s6u
Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin F, et al. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses. Sci Adv. 2018;4:eaar2824 pubmed 出版商
  • 免疫印迹; 人类; 图 ev3c
Zaffagnini G, Savova A, Danieli A, Romanov J, Tremel S, Ebner M, et al. p62 filaments capture and present ubiquitinated cargos for autophagy. EMBO J. 2018;37: pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Wu G, Mu T, Gao Z, Wang J, Sy M, Li C. Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production. J Biol Chem. 2017;292:18747-18759 pubmed 出版商
  • 免疫印迹; 人类; 图 e9d
Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Strickson S, Emmerich C, Goh E, Zhang J, Kelsall I, MacArtney T, et al. Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proc Natl Acad Sci U S A. 2017;114:E3481-E3489 pubmed 出版商
  • 免疫印迹; fruit fly ; 图 4e
Vonk J, Yeshaw W, Pinto F, Faber A, Lahaye L, Kanon B, et al. Drosophila Vps13 Is Required for Protein Homeostasis in the Brain. PLoS ONE. 2017;12:e0170106 pubmed 出版商
  • 免疫印迹; 人类; 图 s7b
Francavilla C, Papetti M, Rigbolt K, Pedersen A, Sigurdsson J, Cazzamali G, et al. Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking. Nat Struct Mol Biol. 2016;23:608-18 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Emmerich C, Bakshi S, Kelsall I, Ortiz Guerrero J, Shpiro N, Cohen P. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem Biophys Res Commun. 2016;474:452-461 pubmed 出版商
  • 免疫印迹; 小鼠
Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed 出版商
  • 免疫沉淀; 人类; 图 s6a, s6b
Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Hochrainer K, Pejanovic N, Olaseun V, Zhang S, Iadecola C, Anrather J. The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Nucleic Acids Res. 2015;43:9889-904 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Mahanic C, Budhavarapu V, Graves J, Li G, Lin W. Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37. J Biol Chem. 2015;290:26508-22 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Zhao J, Molitor T, Langston J, Nichols R. LRRK2 dephosphorylation increases its ubiquitination. Biochem J. 2015;469:107-20 pubmed 出版商
  • 免疫印迹; malaria parasite P. falciparum; 图 2
Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, Estiu G, Stahelin R, et al. A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature. 2015;520:683-7 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Yazlovitskaya E, Tseng H, Viquez O, Tu T, Mernaugh G, McKee K, et al. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015;26:1857-74 pubmed 出版商
  • 免疫印迹; 大鼠; 图 s4
Widagdo J, Chai Y, Ridder M, Chau Y, Johnson R, Sah P, et al. Activity-Dependent Ubiquitination of GluA1 and GluA2 Regulates AMPA Receptor Intracellular Sorting and Degradation. Cell Rep. 2015;10:783-795 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Kanayama M, Inoue M, Danzaki K, Hammer G, He Y, Shinohara M. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nat Commun. 2015;6:5779 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1,000
Shiba Fukushima K, Inoshita T, Hattori N, Imai Y. Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy. J Biol Chem. 2014;289:33131-6 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. EMBO J. 2014;33:2581-96 pubmed 出版商
  • 免疫印迹; 人类; 图 3, 4, 5
Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed 出版商
  • 免疫印迹; 小鼠
Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis. Toxicology. 2014;322:43-50 pubmed 出版商
Wang W, Hu D, Feng Y, Wu C, Song Y, Liu W, et al. Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome. BMC Biol. 2020;18:182 pubmed 出版商
Wu H, Shi L, Zhang Y, Peng X, Zheng T, Li Y, et al. Ubiquitination Is Essential for Avibirnavirus Replication by Supporting VP1 Polymerase Activity. J Virol. 2019;93: pubmed 出版商
Liu J, Yuan Y, Xu J, Xiao K, Xu Y, Guo T, et al. β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling. Front Immunol. 2018;9:2930 pubmed 出版商
Conte C, Griffis E, Hickson I, Pérez Oliva A. USP45 and Spindly are part of the same complex implicated in cell migration. Sci Rep. 2018;8:14375 pubmed 出版商
Robeson A, Lindblom K, Wojton J, Kornbluth S, Matsuura K. Dimer-specific immunoprecipitation of active caspase-2 identifies TRAF proteins as novel activators. EMBO J. 2018;37: pubmed 出版商
Bhattacharjee S, Bose P, Patel K, Roy S, Gain C, Gowda H, et al. Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival. Cell Death Dis. 2018;9:605 pubmed 出版商
Liu Q, Zhang S, Chen G, Zhou H. E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation. Sci Rep. 2017;7:4521 pubmed 出版商
Jiang L, Xiong J, Zhan J, Yuan F, Tang M, Zhang C, et al. Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis. J Biol Chem. 2017;292:13296-13311 pubmed 出版商
Hooper C, Jackson S, Coughlin E, Coon J, Miyamoto S. Covalent modification of the NF-κB essential modulator (NEMO) by a chemical compound can regulate its ubiquitin binding properties in vitro. J Biol Chem. 2014;289:33161-74 pubmed 出版商
Liu N, Li X, Huang H, Zhao C, Liao S, Yang C, et al. Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth. Oncotarget. 2014;5:5453-71 pubmed
Blessing N, Brockman A, Chadee D. The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3. Mol Cell Biol. 2014;34:3132-43 pubmed 出版商
Chen C, Meng Y, Wang L, Wang H, Tian C, Pang G, et al. Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the I?Ba/NF-?B and MKP1/ERK/STAT1 pathways. Immunology. 2014;142:307-19 pubmed 出版商
Zhang J, Ma W, Tian S, Fan Z, Ma X, Yang X, et al. RanBPM interacts with T?RI, TRAF6 and curbs TGF induced nuclear accumulation of T?RI. Cell Signal. 2014;26:162-72 pubmed 出版商
产品信息
SKU号 :
5621S
产品名称 :
K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb
规格 :
100微升
Price-(USD) :
274美元
物种x :
都是
应用 :
免疫印迹
产品种类 :
Ubiquitin and Ubiquitin-like proteins
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
宿主 :
靶标 :
Ubiquitin poly Lys63
最初蛋白 :
泛肽
别名 :
40S ribosomal protein S27a,CEP80,RPS27A,Ribosomal protein S27a,UBA52,UBA80,UBB,UBC,UBCEP1,UBCEP80,UBIQ,ubiquitin and ribosomal protein S27a,ubiquitin carboxyl extension protein 80,ubiquitin-CEP80
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。