产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Notch2(D76A6)XP®兔单克隆抗体
目录 :
5732
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D76A6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1c
Hu J, Yu J, Gan J, Song N, Shi L, Liu J, et al. Notch1/2/3/4 are prognostic biomarker and correlated with immune infiltrates in gastric cancer. Aging (Albany NY). 2020;12:2595-2609 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 f1s3b
Nandagopal N, Santat L, Elowitz M. Cis-activation in the Notch signaling pathway. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2g
  • 免疫印迹; 人类; 1:1000; 图 2e
Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7g
  • 免疫印迹; 人类; 图 7c
Huang G, Jiang H, Lin Y, Wu Y, Cai W, Shi B, et al. lncAKHE enhances cell growth and migration in hepatocellular carcinoma via activation of NOTCH2 signaling. Cell Death Dis. 2018;9:487 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 5b
Ma Q, Wang Y, Zhang T, Zuo W. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy. Life Sci. 2018;193:104-109 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6f
  • 免疫印迹; 人类; 1:1000; 图 3a
Bhardwaj A, Yang Y, Ueberheide B, Smith S. Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation. Nat Commun. 2017;8:2214 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 s2g
  • 免疫印迹; 小鼠; 图 2c
Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6a
Rippe C, Zhu B, Krawczyk K, Bavel E, Albinsson S, Sjölund J, et al. Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway. Sci Rep. 2017;7:1334 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:600
Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  • 免疫印迹; 人类; 图 6d
Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400; 图 3
Liu Z, Brunskill E, Varnum Finney B, Zhang C, Zhang A, Jay P, et al. The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development. 2015;142:2452-63 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  • 免疫组化-石蜡切片; 小鼠; 图 2
Li X, Tao J, Cigliano A, Sini M, Calderaro J, Azoulay D, et al. Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver. Oncotarget. 2015;6:10102-15 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
  • 免疫印迹; 人类; 图 s2
Plessl K, Haider S, Fiala C, Pollheimer J, Knöfler M. Expression pattern and function of Notch2 in different subtypes of first trimester cytotrophoblast. Placenta. 2015;36:365-71 pubmed 出版商
  • 其他; 人类; 图 5b
  • 免疫印迹; 人类; 图 5a
Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Ortega M, Bhatnagar H, Lin A, Wang L, Aster J, Sill H, et al. A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies. Leukemia. 2015;29:968-76 pubmed 出版商
  • 免疫印迹; 人类
So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed 出版商
Otti G, Saleh L, Velicky P, Fiala C, Pollheimer J, Knöfler M. Notch2 controls prolactin and insulin-like growth factor binding protein-1 expression in decidualizing human stromal cells of early pregnancy. PLoS ONE. 2014;9:e112723 pubmed 出版商
Rowe M, Raithatha S, Shannon Lowe C. Counteracting effects of cellular Notch and Epstein-Barr virus EBNA2: implications for stromal effects on virus-host interactions. J Virol. 2014;88:12065-76 pubmed 出版商
Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes R. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Res. 2014;16:R62 pubmed 出版商
Sierra R, Thevenot P, Raber P, Cui Y, Parsons C, Ochoa A, et al. Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer. Cancer Immunol Res. 2014;2:800-11 pubmed 出版商
Wang W, Yao Y, Jiang L, Hu T, Ma J, Ruan Z, et al. Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients. Dis Markers. 2013;35:395-405 pubmed 出版商
Tezgel A, González Pérez G, Telfer J, Osborne B, Minter L, Tew G. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013;21:201-9 pubmed 出版商
产品信息
SKU号 :
5732P
产品名称 :
Notch2(D76A6)XP®兔单克隆抗体
规格 :
40微升
Price-(USD) :
135美元
物种x :
H, M, R
应用 :
流式细胞仪
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
110, 300
宿主 :
靶标 :
Notch2
最初蛋白 :
Notch 2
别名 :
AGS2,NOTC2,NOTCH2,Neurogenic locus notch homolog protein 2,Notch 2,Notch 2 extracellular truncation,Notch 2 intracellular domain,Notch homolog 2 (Drosophila),hN2
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。