| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed 出版商 |
| Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, et al. CHK2-FOXK axis promotes transcriptional control of autophagy programs. Sci Adv. 2020;6:eaax5819 pubmed 出版商 |
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商 |
| Mohamed T, Ang Y, Radzinsky E, Zhou P, Huang Y, Elfenbein A, et al. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018;173:104-116.e12 pubmed 出版商 |
- 免疫细胞化学; 人类; 图 2b
- 免疫印迹; 人类; 图 2b
| Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed 出版商 |
| Stav Noraas T, Edelmann R, Poulsen L, Sundnes O, Phung D, Küchler A, et al. Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery. J Immunol. 2017;198:3318-3325 pubmed 出版商 |
| Muller Durovic B, Lanna A, Covre L, Mills R, Henson S, Akbar A. Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein Kinase. J Immunol. 2016;197:2891-2899 pubmed 出版商 |
| Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed |
| Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed 出版商 |
| Heckler M, Zeleke T, Divekar S, Fernandez A, Tiek D, Woodrick J, et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. Oncotarget. 2016;7:47201-47220 pubmed 出版商 |
| He D, Xiang J, Li B, Liu H. The dynamic behavior of Ect2 in response to DNA damage. Sci Rep. 2016;6:24504 pubmed 出版商 |
| Köhler C, Koalick D, Fabricius A, Parplys A, Borgmann K, Pospiech H, et al. Cdc45 is limiting for replication initiation in humans. Cell Cycle. 2016;15:974-85 pubmed 出版商 |
| Chavoshi S, Egorova O, Lacdao I, Farhadi S, Sheng Y, Saridakis V. Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. J Biol Chem. 2016;291:6281-91 pubmed 出版商 |
| Kralovicova J, Knut M, Cross N, Vorechovsky I. Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting. Sci Rep. 2016;6:18741 pubmed 出版商 |
| GarcÃa V, Lara Chica M, Cantarero I, Sterner O, Calzado M, Muñoz E. Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells. Oncotarget. 2016;7:4490-506 pubmed 出版商 |
| Murata Y, Uehara Y, Hosoi Y. Activation of mTORC1 under nutrient starvation conditions increases cellular radiosensitivity in human liver cancer cell lines, HepG2 and HuH6. Biochem Biophys Res Commun. 2015;468:684-90 pubmed 出版商 |
| Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed |
- 免疫印迹; 人类; 1:1000; 图 4c, d
| Xiong Y, Su H, Lv P, Ma Y, Wang S, Miao H, et al. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. Oncotarget. 2015;6:35625-35 pubmed 出版商 |
- 免疫细胞化学; 人类; 图 7
- 免疫印迹; 人类; 图 7
| Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed 出版商 |
| Wang L, Liu R, Ye P, Wong C, Chen G, Zhou P, et al. Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation. Nat Commun. 2015;6:5909 pubmed 出版商 |
| Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed 出版商 |
| Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed 出版商 |
| Stimpson K, Sullivan L, Kuo M, Sullivan B. Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function. PLoS ONE. 2014;9:e92432 pubmed 出版商 |
| Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed 出版商 |
| Ding S, Diep J, Feng N, Ren L, Li B, Ooi Y, et al. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nat Commun. 2018;9:1485 pubmed 出版商 |
| Borodkina A, Shatrova A, Deryabin P, Griukova A, Abushik P, Antonov S, et al. Calcium alterations signal either to senescence or to autophagy induction in stem cells upon oxidative stress. Aging (Albany NY). 2016;8:3400-3418 pubmed 出版商 |
| Zhao C, Chen X, Zang D, Lan X, Liao S, Yang C, et al. Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy. Biochem Pharmacol. 2016;116:22-38 pubmed 出版商 |
| Ambati S, Shieh J, Pera B, Lopes E, Chaudhry A, Wong E, et al. BO-1055, a novel DNA cross-linking agent with remarkable low myelotoxicity shows potent activity in sarcoma models. Oncotarget. 2016;7:43062-43075 pubmed 出版商 |
| Borodkina A, Shatrova A, Deryabin P, Grukova A, Nikolsky N, Burova E. Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition. Cell Cycle. 2016;15:117-27 pubmed 出版商 |
| Boysen G, Barbieri C, Prandi D, Blattner M, Chae S, Dahija A, et al. SPOP mutation leads to genomic instability in prostate cancer. elife. 2015;4: pubmed 出版商 |
| Schoors S, Bruning U, Missiaen R, Queiroz K, Borgers G, Elia I, et al. Fatty acid carbon is essential for dNTP synthesis in endothelial cells. Nature. 2015;520:192-197 pubmed 出版商 |
| Hattori H, Janky R, Nietfeld W, Aerts S, Madan Babu M, Venkitaraman A. p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response. Cell Cycle. 2014;13:2572-86 pubmed 出版商 |
| Kilic Eren M, Tabor V. The role of hypoxia inducible factor-1 alpha in bypassing oncogene-induced senescence. PLoS ONE. 2014;9:e101064 pubmed 出版商 |
| Krześniak M, Zajkowicz A, Matuszczyk I, Rusin M. Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D. Mech Ageing Dev. 2014;139:11-21 pubmed 出版商 |
| Airik R, Slaats G, Guo Z, Weiss A, Khan N, Ghosh A, et al. Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling. J Am Soc Nephrol. 2014;25:2573-83 pubmed 出版商 |
| Lu L, Xiong Y, Kuang H, Korakavi G, Yu X. Regulation of the DNA damage response on male meiotic sex chromosomes. Nat Commun. 2013;4:2105 pubmed 出版商 |
| Tang H, Sampath P, Yan X, Thorne S. Potential for enhanced therapeutic activity of biological cancer therapies with doxycycline combination. Gene Ther. 2013;20:770-8 pubmed 出版商 |
| Hazawa M, Hosokawa Y, Monzen S, Yoshino H, Kashiwakura I. Regulation of DNA damage response and cell cycle in radiation-resistant HL60 myeloid leukemia cells. Oncol Rep. 2012;28:55-61 pubmed 出版商 |
