产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
β-Amyloid (D54D2) XP® Rabbit mAb
目录 :
8243
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D54D2
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-自由浮动切片
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 4c
Nies S, Takahashi H, Herber C, Huttner A, Chase A, Strittmatter S. Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β. J Biol Chem. 2021;297:101159 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:400; 图 4e
Dá Mesquita S, Herz J, Wall M, Dykstra T, de Lima K, Norris G, et al. Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology. Sci Adv. 2021;7: pubmed 出版商
  • 免疫组化; 小鼠; 图 s3b
Son G, Yoo S, Kang S, Rasheed A, Jung D, Park H, et al. Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice. Alzheimers Res Ther. 2021;13:4 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3e
Huang Z, Zhao J, Wang W, Zhou J, Zhang J. Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease. Front Cell Neurosci. 2020;14:28 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2000; 图 s7b
Gate D, Saligrama N, Leventhal O, Yang A, Unger M, Middeldorp J, et al. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. 2020;577:399-404 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1a
Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, et al. Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis. Front Neurosci. 2019;13:925 pubmed 出版商
  • 免疫组化; 人类; 1:500
Mathys H, Davila Velderrain J, Peng Z, Gao F, Mohammadi S, Young J, et al. Single-cell transcriptomic analysis of Alzheimer's disease. Nature. 2019;570:332-337 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 3c
Martorell A, Paulson A, Suk H, Abdurrob F, Drummond G, Guan W, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. 2019;177:256-271.e22 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:250
Brai E, Alina Raio N, Alberi L. Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease. Acta Neuropathol Commun. 2016;4:64 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 4
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 4
  • 免疫印迹; 小鼠; 1:4000; 图 4
Beck S, Guo L, Phensy A, Tian J, Wang L, Tandon N, et al. Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease. Nat Commun. 2016;7:11483 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Corbett G, Gonzalez F, Pahan K. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015;112:8445-50 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 7
Zhao Z, Sagare A, Ma Q, Halliday M, Kong P, Kisler K, et al. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015;18:978-87 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, et al. Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2015;94:1-9 pubmed 出版商
Piccialli I, Tedeschi V, Caputo L, Amato G, De Martino L, De Feo V, et al. The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ1-42 Oligomers in Primary Cortical Neurons. Antioxidants (Basel). 2021;10: pubmed 出版商
Wu Y, Wu H, Zeng J, Pluimer B, Dong S, Xie X, et al. Mild traumatic brain injury induces microvascular injury and accelerates Alzheimer-like pathogenesis in mice. Acta Neuropathol Commun. 2021;9:74 pubmed 出版商
Su Q, Li T, He P, Lu X, Yu Q, Gao Q, et al. Trichostatin A ameliorates Alzheimer's disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice. Alzheimers Res Ther. 2021;13:7 pubmed 出版商
Rao C, Asch A, Carr D, Yamada H. "Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease. Aging Cell. 2020;19:e13109 pubmed 出版商
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed 出版商
Dá Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison R, Kingsmore K, et al. Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature. 2018;560:185-191 pubmed 出版商
Rao C, Farooqui M, Zhang Y, Asch A, Yamada H. Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model. Aging Cell. 2018;:e12797 pubmed 出版商
Lin Y, Seo J, Gao F, Feldman H, Wen H, Penney J, et al. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types. Neuron. 2018;98:1141-1154.e7 pubmed 出版商
Dai C, Hu W, Tung Y, Liu F, Gong C, Iqbal K. Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice. Alzheimers Res Ther. 2018;10:13 pubmed 出版商
Salazar S, Gallardo C, Kaufman A, Herber C, Haas L, Robinson S, et al. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. J Neurosci. 2017;37:9207-9221 pubmed 出版商
Lu L, Guo L, Gauba E, Tian J, Wang L, Tandon N, et al. Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice. PLoS ONE. 2015;10:e0144068 pubmed 出版商
Kim J, Yun H, Jin P, Lee H, Han J, Udumula V, et al. Inhibitory effect of a 2,4-bis(4-hydroxyphenyl)-2-butenal diacetate on neuro-inflammatory reactions via inhibition of STAT1 and STAT3 activation in cultured astrocytes and microglial BV-2 cells. Neuropharmacology. 2014;79:476-87 pubmed 出版商
产品信息
SKU号 :
8243S
产品名称 :
β-Amyloid (D54D2) XP® Rabbit mAb
规格 :
100微升
Price-(USD) :
260美元
物种x :
H, M
应用 :
免疫荧光(石蜡)
产品种类 :
神经科学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
5
宿主 :
靶标 :
淀粉样蛋白前体
最初蛋白 :
淀粉样蛋白前体
别名 :
A4,AAA,ABETA,ABPP,AD1,AICD-50,AICD-57,AICD-59,AID(50),AID(57),AID(59),APP,APPI,Alzheimer disease amyloid protein,Amyloid beta A4 protein,Amyloid intracellular domain 50,Amyloid intracellular domain 57,Amyloid intracellular domain 59,Beta-APP40,Beta-APP42,Beta-amyloid protein 40,Beta-amyloid protein 42,C31,C80,C83,C99,CTFgamma,CVAP,Cerebral vascular amyloid peptide,Gamma-CTF(50),Gamma-CTF(57),Gamma-CTF(59),Gamma-secretase C-terminal fragment 50,Gamma-secretase C-terminal fragment 57,Gamma-secretase C-terminal fragment 59,N-APP,P3(40),P3(42),PN-II,PN2,PreA4,Protease nexin-II,S-APP-alpha,S-APP-beta,Soluble APP-alpha,Soluble APP-beta,amyloid beta (A4) precursor protein,beta-amyloid peptide,peptidase nexin-II
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。