产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Non-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) Rabbit mAb
目录 :
8814
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D13A1
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验, 其他
文章摘录数: 66
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 7a
Tang Y, Dong L, Zhang C, Li X, Li R, Lin H, et al. PRMT5 acts as a tumor suppressor by inhibiting Wnt/β-catenin signaling in murine gastric tumorigenesis. Int J Biol Sci. 2022;18:4329-4340 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 8d
  • 免疫印迹; 人类; 图 3d, 8e
Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, et al. Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Cell Death Dis. 2021;12:912 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 9c
Ma X, Takahashi Y, Wu W, Liang W, Chen J, Chakraborty D, et al. ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021;297:101185 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6j
Arnold F, Mahaddalkar P, Kraus J, Zhong X, Bergmann W, Srinivasan D, et al. Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration. Adv Sci (Weinh). 2021;8:2100626 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 3e
  • 免疫印迹; 人类; 1:2000; 图 1k, 2e
  • 免疫组化-石蜡切片; 大鼠; 1:200; 图 7c
Shen J, Sun Y, Liu X, Zhu Y, Bao B, Gao T, et al. EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling. Stem Cell Res Ther. 2021;12:415 pubmed 出版商
  • 免疫组化; 小鼠; 图 7b
Wang Y, Su Y, Yu G, Wang X, Chen X, Yu B, et al. Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Adv Sci (Weinh). 2021;8:e2101181 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4d
Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b, 6a
Ianni A, Hofmann M, Kumari P, Tarighi S, Al tamari H, Görgens A, et al. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:639162 pubmed 出版商
  • 免疫印迹; 人类; 图 7b
  • 免疫印迹; 小鼠; 图 4a
Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed 出版商
  • 免疫组化; 小鼠; 1:1600; 图 s8-2a
Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5b, 5e
Yang J, Kitami M, Pan H, Nakamura M, Zhang H, Liu F, et al. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Sci Signal. 2021;14: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed 出版商
  • 免疫印迹; 人类; 图 5i
Rinastiti P, Ikeda K, Rahardini E, Miyagawa K, Tamada N, Kuribayashi Y, et al. Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition. PLoS ONE. 2020;15:e0226049 pubmed 出版商
  • 免疫组化; 人类; 图 6a
Kluz P, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, et al. Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Oncogene. 2020;39:2877-2889 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9b
Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 7e
  • 免疫印迹; 小鼠; 1:1000; 图 s7d
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s2a
Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800; 图 3s2c
  • 免疫印迹; 人类; 1:1000; 图 8s1d
Diaz Osterman C, Ozmadenci D, Kleinschmidt E, Taylor K, Barrie A, Jiang S, et al. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 图 6b
  • 免疫印迹; 小鼠; 图 6a
Huang K, Ru B, Zhang Y, Chan W, Chow S, Zhang J, et al. Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation. FASEB J. 2019;33:7588-7602 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4g
Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, et al. ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018;9:4582 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 4d
Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s4c
  • 其他; 小鼠; 1:500; 图 8j
  • 免疫印迹; 小鼠; 1:2000; 图 8g
Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4b
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Frey J, Kim S, Li Z, Wolfgang M, Riddle R. β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice. Endocrinology. 2018;159:272-284 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3g
Matsumoto Y, La Rose J, Lim M, Adissu H, Law N, Mao X, et al. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. J Clin Invest. 2017;127:2612-2625 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5b
  • 免疫印迹; 小鼠; 图 5c
Dogan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Domingues M, Martinez Sanz J, Papon L, Larue L, Mouawad L, Bonaventure J. Structure-based mutational analysis of ICAT residues mediating negative regulation of ?-catenin co-transcriptional activity. PLoS ONE. 2017;12:e0172603 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow J, et al. Decreased WNT/?-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Hum Mol Genet. 2017;26:333-343 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 s5h
Beyer S, Pontis J, Schirwis E, Battisti V, Rudolf A, Le Grand F, et al. Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation. Cell Discov. 2016;2:16037 pubmed
  • 免疫印迹; 人类; 1:5000; 图 1b
Gammons M, Rutherford T, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016;129:3892-3902 pubmed
  • 免疫印迹; 人类; 图 6a
Kong X, Liu F, Gao J. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways. Oncotarget. 2016;7:66051-66060 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6c
Hofbauer P, Jung J, McArdle T, Ogle B. Simple Monolayer Differentiation of Murine Cardiomyocytes via Nutrient Deprivation-Mediated Activation of β-Catenin. Stem Cell Rev. 2016;12:731-743 pubmed
  • 免疫印迹; 人类; 1:4000; 图 6
Jiang S, Chen G, Feng L, Jiang Z, Yu M, Bao J, et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep. 2016;14:1891-900 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4e
Jacobsen A, Heijmans N, Verkaar F, Smit M, Heringa J, van Amerongen R, et al. Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling. PLoS ONE. 2016;11:e0155743 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 0.5 ug/ml; 图 st1
  • 免疫印迹; 人类; 图 2
Kaur A, Webster M, Marchbank K, Behera R, Ndoye A, Kugel C, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016;532:250-4 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 s7
  • 免疫细胞化学; 小鼠; 1:800; 图 s7
Beyaz S, Mana M, Roper J, Kedrin D, Saadatpour A, Hong S, et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. 2016;531:53-8 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Cui H, Wang S, Miao J, Fu Z, Feng F, Wu J, et al. CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signaling. Oncotarget. 2016;7:5613-29 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 6d
Goodnough L, Dinuoscio G, ATIT R. Twist1 contributes to cranial bone initiation and dermal condensation by maintaining Wnt signaling responsiveness. Dev Dyn. 2016;245:144-56 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2a
Abshagen K, Senne M, Genz B, Thomas M, Vollmar B. Differential Effects of Axin2 Deficiency on the Fibrogenic and Regenerative Response in Livers of Bile Duct-Ligated Mice. Eur Surg Res. 2015;55:328-340 pubmed
  • 免疫印迹; 人类; 1:1000; 图 3c
Ma S, Yang L, Niu T, Cheng C, Zhong L, Zheng M, et al. SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML. Sci Rep. 2015;5:15646 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫组化; 人类
  • 免疫印迹; 人类; 图 4
Xiong W, Zhang L, Yu L, Xie W, Man Y, Xiong Y, et al. Estradiol promotes cells invasion by activating β-catenin signaling pathway in endometriosis. Reproduction. 2015;150:507-16 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3C
Mathur R, Sehgal L, Braun F, Berkova Z, Romaguerra J, Wang M, et al. Targeting Wnt pathway in mantle cell lymphoma-initiating cells. J Hematol Oncol. 2015;8:63 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2e
Dow L, Fisher J, O Rourke K, Muley A, Kastenhuber E, Livshits G, et al. Inducible in vivo genome editing with CRISPR-Cas9. Nat Biotechnol. 2015;33:390-394 pubmed 出版商
  • 抑制或激活实验; 人类; 图 5b
Traenkle B, Emele F, Anton R, Poetz O, Haeussler R, Maier J, et al. Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Mol Cell Proteomics. 2015;14:707-23 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
  • 免疫印迹; 小鼠; 图 4
Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Valkenburg K, Yu X, De Marzo A, Spiering T, Matusik R, Williams B. Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia. Prostate. 2014;74:1506-20 pubmed 出版商
Di Franco S, Bianca P, Sardina D, Turdo A, Gaggianesi M, Veschi V, et al. Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery. Nat Commun. 2021;12:5006 pubmed 出版商
Raisch J, Côté Biron A, Langlois M, Leblanc C, Rivard N. Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis. Cells. 2021;10: pubmed 出版商
Aripaka K, Gudey S, Zang G, Schmidt A, Åhrling S, Österman L, et al. TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer. EBioMedicine. 2019;: pubmed 出版商
MacDougall M, Clarke R, Merrill B. Intracellular Ca2+ Homeostasis and Nuclear Export Mediate Exit from Naive Pluripotency. Cell Stem Cell. 2019;: pubmed 出版商
Lun X, Szklarczyk D, Gábor A, Dobberstein N, Zanotelli V, Saez Rodriguez J, et al. Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. Mol Cell. 2019;74:1086-1102.e5 pubmed 出版商
Knight M, Karuppaiah K, Lowe M, Mohanty S, Zondervan R, Bell S, et al. R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass. Bone Res. 2018;6:24 pubmed 出版商
Latifi Z, Fattahi A, Hamdi K, Ghasemzadeh A, Karimi P, Nejabati H, et al. Wnt Signaling Pathway in Uterus of Normal and Seminal Vesicle Excised Mated Mice during Pre-implantation Window. Geburtshilfe Frauenheilkd. 2018;78:412-422 pubmed 出版商
Hadjadj D, Kim S, Denecker T, Ben Driss L, Cadoret J, Maric C, et al. A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas. Aging (Albany NY). 2017;9:2695-2716 pubmed 出版商
Wang H, Ren Y, Hu X, Ma M, Wang X, Liang H, et al. Effect of Wnt Signaling on the Differentiation of Islet ?-Cells from Adipose-Derived Stem Cells. Biomed Res Int. 2017;2017:2501578 pubmed 出版商
Ragni C, Diguet N, Le Garrec J, Novotova M, Resende T, Pop S, et al. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017;8:14582 pubmed 出版商
Softic S, Boucher J, Solheim M, Fujisaka S, Haering M, Homan E, et al. Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. Diabetes. 2016;65:2187-200 pubmed 出版商
Kaushal G, Rognoni E, Lichtenberger B, Driskell R, Kretzschmar K, Hoste E, et al. Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. J Invest Dermatol. 2015;135:2926-2934 pubmed 出版商
Arthur S, Zwetsloot K, Lawrence M, Nieman D, Lila M, Grace M, et al. Ajuga turkestanica increases Notch and Wnt signaling in aged skeletal muscle. Eur Rev Med Pharmacol Sci. 2014;18:2584-92 pubmed
Gauger K, Bassa L, Henchey E, Wyman J, Ser Dolansky J, Shimono A, et al. The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1. Mol Cancer. 2014;13:117 pubmed 出版商
产品信息
SKU号 :
8814S
产品名称 :
Non-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) Rabbit mAb
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, M, R, Mk, (C, X, Z, B, Dg, Pg, GP, Hr)
应用 :
染色质免疫沉淀
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
92
宿主 :
靶标 :
Catenin-beta (Ser33/Ser37/Thr41) non-phosphate
最初蛋白 :
CTNNB1
别名 :
Beta-catenin,CTNB1,CTNNB,CTNNB1,Catenin beta-1,DKFZp686D02253,FLJ25606,FLJ37923,catenin (cadherin-associated protein), beta 1, 88kDa
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。