产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Phospho-Akt1 (Ser473) (D7F10) XP® Rabbit mAb (Akt1 Specific)
目录 :
9018
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
D7F10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫印迹基因敲除验证
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1n
Yin H, Wang J, Li H, Yu Y, Wang X, Lu L, et al. Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness. Nat Commun. 2021;12:4230 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7b
Shang P, Stepicheva N, Teel K, McCauley A, Fitting C, Hose S, et al. βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells. Commun Biol. 2021;4:850 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠; 图 1a
Wan X, Zhou M, Huang F, Zhao N, Chen X, Wu Y, et al. AKT1-CREB stimulation of PDGFRα expression is pivotal for PTEN deficient tumor development. Cell Death Dis. 2021;12:172 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3e
Grundmann S, Schutkowski A, Berger C, Baur A, König B, Stangl G. High-phosphorus diets reduce aortic lesions and cardiomyocyte size and modify lipid metabolism in Ldl receptor knockout mice. Sci Rep. 2020;10:20748 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4a
  • 免疫印迹; 小鼠; 图 2b
Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, et al. Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Rep. 2020;32:108151 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b
Kumar A, Xie L, Ta C, Hinton A, Gunasekar S, Minerath R, et al. SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s9a
Wang M, Tang C, Xing R, Liu X, Han X, Liu Y, et al. WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 1a
Wang J, Zhao W, Guo H, Fang Y, Stockman S, Bai S, et al. AKT isoform-specific expression and activation across cancer lineages. BMC Cancer. 2018;18:742 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s11a
Ubil E, Caskey L, Holtzhausen A, Hunter D, Story C, Earp H. Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response. J Clin Invest. 2018;128:2356-2369 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4f
Protack C, Foster T, Hashimoto T, Yamamoto K, Lee M, Kraehling J, et al. Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency. Sci Rep. 2017;7:15386 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 6b
Yoo S, Latifkar A, Cerione R, Antonyak M. Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. J Biol Chem. 2017;292:3947-3957 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
He X, Liu Z, Xia Y, Xu J, Lv G, Wang L, et al. HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs. Oncotarget. 2017;8:1247-1261 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Weikel K, Cacicedo J, Ruderman N, Ido Y. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016;36: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Major J, Salih M, Tuana B. Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium. J Mol Cell Cardiol. 2015;84:179-90 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, et al. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization. Autophagy. 2015;11:271-84 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Alayev A, Berger S, Kramer M, Schwartz N, Holz M. The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells. J Cell Biochem. 2015;116:450-7 pubmed 出版商
Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed 出版商
Goddard P, Sanchez Garrido J, Slater S, Kalyan M, Ruano Gallego D, Marches O, et al. Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages. Cell Rep. 2019;27:1008-1017.e6 pubmed 出版商
Ryzhakov G, West N, Franchini F, Clare S, Ilott N, Sansom S, et al. Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis. Nat Commun. 2018;9:3797 pubmed 出版商
Sharma M, Braun R. Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis. Development. 2018;145: pubmed 出版商
Jiao X, Velasco Velázquez M, Wang M, Li Z, Rui H, Peck A, et al. CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion. Cancer Res. 2018;78:1657-1671 pubmed 出版商
Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 2018;9:242 pubmed 出版商
Camilli G, Eren E, Williams D, Aimanianda V, Meunier E, Quintin J. Impaired phagocytosis directs human monocyte activation in response to fungal derived β-glucan particles. Eur J Immunol. 2018;48:757-770 pubmed 出版商
Zhang Y, Xie L, Gunasekar S, Tong D, Mishra A, Gibson W, et al. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nat Cell Biol. 2017;19:504-517 pubmed 出版商
Pandya C, Hoda N, Crider A, Peter D, Kutiyanawalla A, Kumar S, et al. Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice. Mol Psychiatry. 2017;22:745-753 pubmed 出版商
Chen B, Tan Z, Gao J, Wu W, Liu L, Jin W, et al. Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer. J Exp Clin Cancer Res. 2015;34:126 pubmed 出版商
产品信息
SKU号 :
9018P
产品名称 :
Phospho-Akt1 (Ser473) (D7F10) XP® Rabbit mAb (Akt1 Specific)
规格 :
40微升
Price-(USD) :
135美元
物种x :
H, M, R
应用 :
流式细胞仪
产品种类 :
PI3K / Akt Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
60
宿主 :
靶标 :
Akt1(Ser473)磷酸盐
最初蛋白 :
Akt1
别名 :
AKT,AKT1,AKT1 kinase,MGC99656,PKB,PKB-ALPHA,PRKBA,Protein kinase B,Proto-oncogene c-Akt,RAC,RAC-ALPHA,RAC-PK-alpha,RAC-alpha serine/threonine-protein kinase,rac protein kinase alpha,v-akt murine thymoma viral oncogene homolog 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。