产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
MEK1/2抗体
目录 :
9122
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1c
Lee S, Jung J, Lee Y, Kim S, Kim J, Kim B, et al. Targeting HSF1 as a Therapeutic Strategy for Multiple Mechanisms of EGFR Inhibitor Resistance in EGFR Mutant Non-Small-Cell Lung Cancer. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 大鼠; 图 7f
Zhang Y, Da Q, Cao S, Yan K, Shi Z, Miao Q, et al. HINT1 (Histidine Triad Nucleotide-Binding Protein 1) Attenuates Cardiac Hypertrophy Via Suppressing HOXA5 (Homeobox A5) Expression. Circulation. 2021;144:638-654 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2e
Catalano A, Adlesic M, Kaltenbacher T, Klar R, Albers J, Seidel P, et al. Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Shaaya M, Fauser J, Zhurikhina A, Conage Pough J, Huyot V, Brennan M, et al. Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 4g
Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 1a
Wu P, Hong S, Starenki D, Oshima K, Shao H, Gestwicki J, et al. Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability. Oncogene. 2020;39:4257-4270 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 e2b
Canon J, Rex K, Saiki A, Mohr C, Cooke K, Bagal D, et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature. 2019;575:217-223 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4g
Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Frischknecht L, Britschgi C, Galliker P, Christinat Y, Vichalkovski A, Gstaiger M, et al. BRAF inhibition sensitizes melanoma cells to α-amanitin via decreased RNA polymerase II assembly. Sci Rep. 2019;9:7779 pubmed 出版商
  • 免疫印迹; 人类; 图 1d, s1b
Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, et al. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019;176:1113-1127.e16 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Choi Y, Park S, Sun Y, Yoo J, Pudupakam R, Foo S, et al. Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis. Nat Microbiol. 2019;4:429-437 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Ye P, Liu J, Xu W, Liu D, Ding X, Le S, et al. Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. Hepatology. 2019;69:1946-1964 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Cao Y, Xu Y, Auchoybur M, Chen W, He S, Qin W, et al. Regulatory role of IKKɑ in myocardial ischemia/reperfusion injury by the determination of M1 versus M2 polarization of macrophages. J Mol Cell Cardiol. 2018;123:1-12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 s1a
Kluss J, Conti M, Kaganovich A, Beilina A, Melrose H, Cookson M, et al. Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity. NPJ Parkinsons Dis. 2018;4:13 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7a
Xiong X, Liu Y, Mei Y, Peng J, Wang Z, Kong B, et al. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7a
Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Wang Z, Guo Q, Wang R, Xu G, Li P, Sun Y, et al. The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells. J Hematol Oncol. 2016;9:130 pubmed
  • 免疫印迹; 人类; 图 s12
Ando T, Yamayoshi S, Tomita Y, Watanabe S, Watanabe T, Kawaoka Y. The host protein CLUH participates in the subnuclear transport of influenza virus ribonucleoprotein complexes. Nat Microbiol. 2016;1:16062 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Wang C, Guo S, Wang J, Yan X, Farrelly M, Zhang Y, et al. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. Oncotarget. 2016;7:49597-49610 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 4
Terakawa J, Rocchi A, Serna V, Bottinger E, Graff J, Kurita T. FGFR2IIIb-MAPK Activity Is Required for Epithelial Cell Fate Decision in the Lower Müllerian Duct. Mol Endocrinol. 2016;30:783-95 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Xu Z, Mei F, Liu H, Sun C, Zheng Z. C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 s3j
Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed 出版商
  • 免疫印迹; 人类; 图 6
An X, Zhao Z, Luo Y, Zhang R, Tang X, Hao D, et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget. 2016;7:24719-33 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Wu J, Ivanov A, Fisher P, Fu Z. Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
  • 免疫印迹; 大鼠; 1:1000; 图 5
Yu C, Tang L, Liang C, Chen X, Song S, Ding X, et al. Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
  • 免疫印迹; 人类; 图 5
Park Y, Kim S, Kwon T, Kim J, Song I, Shin H, et al. Peroxiredoxin II promotes hepatic tumorigenesis through cooperation with Ras/Forkhead box M1 signaling pathway. Oncogene. 2016;35:3503-13 pubmed 出版商
Dhawan N, Scopton A, Dar A. Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling. Nature. 2016;537:112-116 pubmed 出版商
产品信息
SKU号 :
9122L
产品名称 :
MEK1/2抗体
规格 :
300微升
Price-(USD) :
574美元
物种x :
H, M, R, Mk, Dm, (C, X)
应用 :
免疫沉淀
产品种类 :
MAP Kinase Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
45
宿主 :
靶标 :
MEK1/MEK2
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。