出版应用/物种/样品/稀释 | 参考文献 |
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| Hakuno D, Kimura M, Ito S, Satoh J, Nakashima Y, Horie T, et al. Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Sci Rep. 2018;8:16749 pubmed 出版商
|
| Ubil E, Caskey L, Holtzhausen A, Hunter D, Story C, Earp H. Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response. J Clin Invest. 2018;128:2356-2369 pubmed 出版商
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| Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A. 2018;115:E2801-E2810 pubmed 出版商
|
| Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed 出版商
|
| Penafuerte C, Feldhammer M, Mills J, Vinette V, Pike K, Hall A, et al. Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFN? signaling. Oncoimmunology. 2017;6:e1321185 pubmed 出版商
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| Ma J, Sanchez B, Hall D, Tremblay A, Di Marco S, Gallouzi I. STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner. EMBO Mol Med. 2017;9:622-637 pubmed 出版商
|
| Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed 出版商
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- 免疫印迹; 人类; 图 2b
- 免疫印迹; 小鼠; 图 2a
| Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed 出版商
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| Fitter S, Matthews M, Martin S, Xie J, Ooi S, Walkley C, et al. mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation. Mol Cell Biol. 2017;37: pubmed 出版商
|
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
|
| Huang C, Lee C, Lin H, Chang J. Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors. Sci Rep. 2016;6:29256 pubmed 出版商
|
| Beck D, Zobel J, Barber R, Evans S, Lezina L, Allchin R, et al. Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma. J Biol Chem. 2016;291:16686-98 pubmed 出版商
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- 流式细胞仪; 小鼠; 图 6a
- 免疫印迹; 小鼠; 1:1000; 图 2b
| Welte T, Kim I, Tian L, Gao X, Wang H, Li J, et al. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016;18:632-44 pubmed 出版商
|
| Jahani Asl A, Yin H, Soleimani V, Haque T, Luchman H, Chang N, et al. Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nat Neurosci. 2016;19:798-806 pubmed 出版商
|
| Pandiri I, Chen Y, Joe Y, Kim H, Park J, Chung H, et al. Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells. Breast Cancer Res Treat. 2016;156:57-64 pubmed 出版商
|
| Däbritz J, Judd L, Chalinor H, Menheniott T, Giraud A. Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells. Sci Rep. 2016;6:20584 pubmed 出版商
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- immunohistochemistry - free floating section; 大鼠; 1:300
| Moravcová S, ÄŒervená K, PaÄesová D, Bendová Z. Identification of STAT3 and STAT5 proteins in the rat suprachiasmatic nucleus and the Day/Night difference in astrocytic STAT3 phosphorylation in response to lipopolysaccharide. J Neurosci Res. 2016;94:99-108 pubmed 出版商
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| Singh P, Sharma P, Sahakyan K, Davison D, Sert Kuniyoshi F, Romero Corral A, et al. Differential effects of leptin on adiponectin expression with weight gain versus obesity. Int J Obes (Lond). 2016;40:266-74 pubmed 出版商
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- 免疫印迹; 人类; 图 1e
- 免疫印迹; 小鼠; 图 1b
| Ulaganathan V, Sperl B, Rapp U, Ullrich A. Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site. Nature. 2015;528:570-4 pubmed 出版商
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| Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed 出版商
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| Chiang C, Uzoma I, Lane D, MemiÅ¡ević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed 出版商
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| Kauko O, Laajala T, Jumppanen M, Hintsanen P, Suni V, Haapaniemi P, et al. Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling. Sci Rep. 2015;5:13099 pubmed 出版商
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- 免疫组化-石蜡切片; 小鼠; 1:80; 图 1a
| Pencik J, Schlederer M, Gruber W, Unger C, Walker S, Chalaris A, et al. STAT3 regulated ARF expression suppresses prostate cancer metastasis. Nat Commun. 2015;6:7736 pubmed 出版商
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| Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 2015;6:14796-813 pubmed
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| Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed 出版商
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| Marozin S, Altomonte J, Muñoz Ãlvarez K, Rizzani A, De Toni E, Thasler W, et al. STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma. Cancer Gene Ther. 2015;22:317-25 pubmed 出版商
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| Pozo K, Hillmann A, Augustyn A, Plattner F, Hai T, Singh T, et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 2015;6:12080-93 pubmed
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- 免疫印迹; 大鼠; 图 7a
- 免疫印迹; 小鼠; 图 7b
| Brulhart Meynet M, Braunersreuther V, Brinck J, Montecucco F, Prost J, Thomas A, et al. Improving reconstituted HDL composition for efficient post-ischemic reduction of ischemia reperfusion injury. PLoS ONE. 2015;10:e0119664 pubmed 出版商
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- 染色质免疫沉淀
; 人类; 1:100; 图 5c
| Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed 出版商
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| Harris R, Apolzan J. Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. Physiol Behav. 2015;138:208-18 pubmed 出版商
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- 免疫组化; 人类; 1:100
- 免疫印迹; 人类; 1:1000
| Lee K, Yeo S, Sung C, Kim S. Twist1 is a key regulator of cancer-associated fibroblasts. Cancer Res. 2015;75:73-85 pubmed 出版商
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| Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed 出版商
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| Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed 出版商
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| Wu T, Ye Y, Min S, Zhu J, Khobahy E, Zhou J, et al. Prevention of murine lupus nephritis by targeting multiple signaling axes and oxidative stress using a synthetic triterpenoid. Arthritis Rheumatol. 2014;66:3129-39 pubmed 出版商
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| Delgado O, Batten K, Richardson J, Xie X, Gazdar A, Kaisani A, et al. Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res. 2014;20:1610-22 pubmed 出版商
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| Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-?B. J Hepatol. 2014;60:306-12 pubmed 出版商
|
| Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni R, Florio T, et al. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures. Cell Cycle. 2013;12:491-500 pubmed 出版商
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| Kanayama M, Hayano T, Koebis M, Maeda T, Tabe Y, Horie S, et al. Hyperactive mTOR induces neuroendocrine differentiation in prostate cancer cell with concurrent up-regulation of IRF1. Prostate. 2017;77:1489-1498 pubmed 出版商
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| Leidgens V, Proske J, Rauer L, Moeckel S, Renner K, Bogdahn U, et al. Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation. Oncotarget. 2017;8:8250-8263 pubmed 出版商
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| Kishi Y, Kondo T, Xiao S, Yosef N, Gaublomme J, Wu C, et al. Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. J Exp Med. 2016;213:2489-2501 pubmed
|
| Beer A, Zenzmaier C, Schreinlechner M, Haas J, Dietrich M, Herz J, et al. Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this large LDL receptor family member. Oncotarget. 2016;7:68721-68733 pubmed 出版商
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| Kim R, Kaushik N, Suh Y, Yoo K, Cui Y, Kim M, et al. Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer. Oncotarget. 2016;7:53430-53442 pubmed 出版商
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| Zhao J, Di T, Wang Y, Liu X, Liang D, Zhang G, et al. Multi-glycoside of Tripterygium wilfordii Hook. f. ameliorates imiquimod-induced skin lesions through a STAT3-dependent mechanism involving the inhibition of Th17-mediated inflammatory responses. Int J Mol Med. 2016;38:747-57 pubmed 出版商
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| Wu P, Wu D, Zhao L, Huang L, Shen G, Huang J, et al. Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis. Oncotarget. 2016;7:19863-83 pubmed 出版商
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| Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed 出版商
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| Qian H, Deng X, Huang Z, Wei J, Ding C, Feng R, et al. An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells. Cell Res. 2015;25:930-45 pubmed 出版商
|
| Yamamoto Y, De Velasco M, Kura Y, Nozawa M, Hatanaka Y, Oki T, et al. Evaluation of in vivo responses of sorafenib therapy in a preclinical mouse model of PTEN-deficient of prostate cancer. J Transl Med. 2015;13:150 pubmed 出版商
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| Basu R, Whitley S, Bhaumik S, Zindl C, Schoeb T, Benveniste E, et al. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol. 2015;16:286-95 pubmed 出版商
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| Moisan A, Lee Y, Zhang J, Hudak C, Meyer C, Prummer M, et al. White-to-brown metabolic conversion of human adipocytes by JAK inhibition. Nat Cell Biol. 2015;17:57-67 pubmed 出版商
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| Judd L, Menheniott T, Ling H, Jackson C, Howlett M, Kalantzis A, et al. Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo. PLoS ONE. 2014;9:e95993 pubmed 出版商
|
| Joshi A, Mahfooz S, Maurya V, Kumar V, Basanna C, Kaur G, et al. PARP1 during embryo implantation and its upregulation by oestradiol in mice. Reproduction. 2014;147:765-80 pubmed 出版商
|
| Bravard A, Vial G, Chauvin M, Rouille Y, Bailleul B, Vidal H, et al. FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver. Cell Commun Signal. 2014;12:4 pubmed 出版商
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| Gough D, Koetz L, Levy D. The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation. PLoS ONE. 2013;8:e83395 pubmed 出版商
|
| Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer. 2013;109:2714-23 pubmed 出版商
|
| Ludyga N, Englert S, Pflieger K, Rauser S, Braselmann H, Walch A, et al. The impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancer. Mol Cancer. 2013;12:28 pubmed 出版商
|
| Hokenson M, Wang Y, Hawwa R, Huang Z, Sharma S, Sanchez Esteban J. Reduced IL-10 production in fetal type II epithelial cells exposed to mechanical stretch is mediated via activation of IL-6-SOCS3 signaling pathway. PLoS ONE. 2013;8:e59598 pubmed 出版商
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| Lee J, Li L, Gretz N, Gebert J, Dihlmann S. Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers. Oncogene. 2012;31:1242-53 pubmed 出版商
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| Schulz I, Engel C, Niestroj A, Zeitschel U, Menge K, Kehlen A, et al. Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-?B signaling pathway. J Neuroinflammation. 2011;8:86 pubmed 出版商
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| Zhou L, Too H. Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth. PLoS ONE. 2011;6:e21680 pubmed 出版商
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| Marsaud V, Tchakarska G, Andrieux G, Liu J, Dembele D, Jost B, et al. Cyclin K and cyclin D1b are oncogenic in myeloma cells. Mol Cancer. 2010;9:103 pubmed 出版商
|