产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化CREB(Ser133)(87G3)兔单克隆抗体
目录 :
9198
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
African green monkey, 人类, 小鼠, 大鼠, , 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他
文章摘录数: 117
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, et al. GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity. Front Neurosci. 2021;15:703044 pubmed 出版商
  • 免疫组化; 小鼠; 图 6c
Cheng C, Xue F, Sui W, Meng L, Xie L, Zhang C, et al. Deletion of natriuretic peptide receptor C alleviates adipose tissue inflammation in hypercholesterolemic Apolipoprotein E knockout mice. J Cell Mol Med. 2021;25:9837-9850 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Wang Q, Qin F, Wang H, Yang H, Liu Q, Li Z, et al. Effect of Electro-Acupuncture at ST36 and SP6 on the cAMP -CREB Pathway and mRNA Expression Profile in the Brainstem of Morphine Tolerant Mice. Front Neurosci. 2021;15:698967 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Lim D, Kim M, Yoon M, Lee J, Lee C, Um M. 1,3-Dicaffeoylquinic Acid as an Active Compound of Arctium lappa Root Extract Ameliorates Depressive-Like Behavior by Regulating Hippocampal Nitric Oxide Synthesis in Ovariectomized Mice. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5f
Gonzalez Rellan M, Fondevila M, Fernandez U, Rodríguez A, Varela Rey M, Veyrat Durebex C, et al. O-GlcNAcylated p53 in the liver modulates hepatic glucose production. Nat Commun. 2021;12:5068 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 6a
  • 免疫印迹; 小鼠; 图 4a
  • 免疫细胞化学; 人类; 图 4c
  • 免疫印迹; 人类; 图 4b
Chen H, Teng Y, Chen X, Liu Z, Geng F, Liu Y, et al. Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase. CNS Neurosci Ther. 2021;27:1300-1312 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3s1g
  • 免疫印迹; 小鼠; 1:1000; 图 4d
Liu Z, Hussien A, Wang Y, Heckmann T, Gonzalez R, Karner C, et al. An adhesion G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 11a
Xiao J, Cai T, Fang Y, Liu R, Flores J, Wang W, et al. Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model. J Neuroinflammation. 2021;18:160 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5m
Swarnkar S, Avchalumov Y, Espadas I, Grinman E, Liu X, Raveendra B, et al. Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. Cell Rep. 2021;36:109369 pubmed 出版商
  • 免疫组化; 大鼠; 图 4a
  • 免疫印迹; 大鼠; 图 2a
Kim Y, Lee J, Kim H, Jang J, Choung Y. Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 图 6d, 6i
Liu L, Xu X, Qu Z, Zhao L, Zhang C, Li Z, et al. Determining 5HT7R's Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine. Front Neurosci. 2021;15:668616 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4l
Basse A, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, et al. Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. Mol Metab. 2021;53:101271 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7e
Qiao Y, Jin T, Guan S, Cheng S, Wen S, Zeng H, et al. Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1. Oncogene. 2021;40:4198-4213 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 10a, 10c
Yan C, Zeng T, Lee K, Nobis M, Loh K, Gou L, et al. Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity. Nat Commun. 2021;12:2622 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1c
Arveseth C, Happ J, Hedeen D, Zhu J, Capener J, Klatt Shaw D, et al. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biol. 2021;19:e3001191 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 3h
  • 免疫印迹; 大鼠; 图 3n
Ruiz Velasco A, Zi M, Hille S, Azam T, Kaur N, Jiang J, et al. Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 图 3f
  • 免疫印迹; 小鼠; 图 3e
Ngamsri K, Jans C, Putri R, Schindler K, Gamper Tsigaras J, Eggstein C, et al. Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation. Front Immunol. 2020;11:407 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Qin Y, Chen W, Jiang G, Zhou L, Yang X, Li H, et al. Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Sci Adv. 2020;6:eaaw9960 pubmed 出版商
  • 免疫印迹; 家羊; 1:1000; 图 s10c
Schiffner R, Bischoff S, Lehmann T, Irintchev A, Nistor M, Lemke C, et al. Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model. Int J Mol Sci. 2020;21: pubmed 出版商
  • 免疫印迹; 人类; 图 6d
Aldonza M, Ku J, Hong J, Kim D, Yu S, Lee M, et al. Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020;6:eaav7416 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1500; 图 1k
Xhima K, Markham Coultes K, Nedev H, Heinen S, Saragovi H, Hynynen K, et al. Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease. Sci Adv. 2020;6:eaax6646 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:800; 图 6s1a
Podyma B, Johnson D, Sipe L, Remcho T, Battin K, Liu Y, et al. The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:800; 图 s4a
Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. 2020;577:676-681 pubmed 出版商
  • 免疫印迹; 小鼠; 图 11h
  • 免疫印迹; 大鼠; 图 10h
Wang X, Deng Y, Gao Y, Dong Y, Wang F, Guan Z, et al. Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway. Aging (Albany NY). 2020;12:543-570 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1m, 5e
  • 免疫印迹; 大鼠; 1:1000; 图 2c
Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, et al. Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation. Aging Cell. 2020;19:e13055 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4f
Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6s1c
Nam H, Jeon S, An H, Yoo J, Lee H, Lee S, et al. Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2k
Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, et al. The mechanosensitive Piezo1 channel is required for bone formation. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Jin H, Xue L, Mo L, Zhang D, Guo X, Xu J, et al. Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. Cell Adh Migr. 2019;13:236-248 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, et al. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019;5:eaaw3593 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1b
Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5e
Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jahn K, et al. TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone. Nat Commun. 2019;10:1354 pubmed 出版商
  • 免疫印迹; 人类; 图 s4f
Du H, LE Y, Sun F, Li K, Xu Y. ILF2 Directly Binds and Stabilizes CREB to Stimulate Malignant Phenotypes of Liver Cancer Cells. Anal Cell Pathol (Amst). 2019;2019:1575031 pubmed 出版商
  • 其他; 小鼠; 1:50; 图 3b
Joy M, Ben Assayag E, Shabashov Stone D, Liraz Zaltsman S, Mazzitelli J, Arenas M, et al. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019;176:1143-1157.e13 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 7c
  • 免疫印迹; 小鼠; 1:2000; 图 1g
Walia M, Taylor S, Ho P, Martin T, Walkley C. Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. Cell Death Dis. 2018;9:844 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 7j
  • 免疫印迹; 人类; 1:1000; 图 s7b
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2i
Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, et al. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med. 2018;24:814-822 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:300; 图 7g
  • 免疫印迹; 大鼠; 1:1000; 图 5d
Zhang P, Bi R, Gan Y. Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats. J Neuroinflammation. 2018;15:117 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Markussen L, Winther S, Wicksteed B, Hansen J. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep. 2018;8:3469 pubmed 出版商
  • 免疫印迹; 人类; 图 s2a
  • 免疫印迹; 小鼠; 图 4a
Sutavani R, Phair I, Barker R, McFarlane A, Shpiro N, Lang S, et al. Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases. J Biol Chem. 2018;293:2302-2317 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
  • 免疫组化-自由浮动切片; 大鼠; 图 6b
Balan I, Warnock K, Puche A, GONDRE LEWIS M, Aurelian L. Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity. Brain Behav Immun. 2018;69:139-153 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4a
Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018;43:407-419 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Cai X, Yuan Y, Liao Z, Xing K, Zhu C, Xu Y, et al. α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway. FASEB J. 2018;32:488-499 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6o
Shi Y, Zhang X, Chen C, Tang M, Wang Z, Liang X, et al. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain Behav Immun. 2017;66:244-256 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3g
Tsuda T, Takefuji M, Wettschureck N, Kotani K, Morimoto R, Okumura T, et al. Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction. J Exp Med. 2017;214:1877-1888 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1c
Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Strickson S, Emmerich C, Goh E, Zhang J, Kelsall I, MacArtney T, et al. Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proc Natl Acad Sci U S A. 2017;114:E3481-E3489 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 8A
Wang S, Stanika R, Wang X, Hagen J, Kennedy M, Obermair G, et al. Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses. J Neurosci. 2017;37:4679-4691 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2b
Dong E, Bachleda A, Xiong Y, Osawa S, Weiss E. Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice. Mol Vis. 2017;23:90-102 pubmed
  • 免疫细胞化学; 人类; 图 s1
Loo L, Bougen Zhukov N, Tan W. Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. Sci Rep. 2017;7:43541 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5a
  • 免疫印迹; 人类; 图 4a
Bu Q, Wang A, Hamzah H, Waldman A, Jiang K, Dong Q, et al. CREB Signaling Is Involved in Rett Syndrome Pathogenesis. J Neurosci. 2017;37:3671-3685 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3b
Akhmedov D, Mendoza Rodriguez M, Rajendran K, Rossi M, Wess J, Berdeaux R. Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Li Y, Buijs Gladdines J, Cant Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2a,s3a
Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Park J, Kim S, Yoo J, Jang J, Lee A, Oh J, et al. Novel Neuroprotective Effects of Melanin-Concentrating Hormone in Parkinson's Disease. Mol Neurobiol. 2017;54:7706-7721 pubmed 出版商
  • 免疫印迹; 犬; 表 1
Bulldan A, Shihan M, Goericke Pesch S, Scheiner Bobis G. Signaling events associated with gonadotropin releasing hormone-agonist-induced hormonal castration and its reversal in canines. Mol Reprod Dev. 2016;83:1092-1101 pubmed 出版商
  • 免疫细胞化学; 犬; 1:200; 图 s6a
  • 免疫印迹; 人类; 1:1000; 图 8f
Eccles R, Czajkowski M, Barth C, Müller P, McShane E, Grunwald S, et al. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun. 2016;7:12963 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:800; 图 1
  • 免疫印迹; 大鼠; 1:1000; 图 1
Yan X, Liu J, Ye Z, Huang J, He F, Xiao W, et al. CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. PLoS ONE. 2016;11:e0162784 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • 免疫印迹; 小鼠; 图 4b
Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
  • 免疫印迹; 人类; 图 2a
François S, Sen N, Mitton B, Xiao X, Sakamoto K, Arvin A. Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral Replication In Vitro and Skin Pathogenesis In Vivo. J Virol. 2016;90:8686-97 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Qiao Y, Qian Y, Wang J, Tang X. Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cells. Oncol Lett. 2016;11:3702-3708 pubmed
  • 免疫印迹; 小鼠; 图 6
Tejada T, Tan L, Torres R, Calvert J, Lambert J, Zaidi M, et al. IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction. Proc Natl Acad Sci U S A. 2016;113:6949-54 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4
Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed 出版商
  • 免疫组化; 大鼠; 图 3a
  • 免疫印迹; 大鼠; 图 2a
Bulldan A, Dietze R, Shihan M, Scheiner Bobis G. Non-classical testosterone signaling mediated through ZIP9 stimulates claudin expression and tight junction formation in Sertoli cells. Cell Signal. 2016;28:1075-85 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Natale C, Duperret E, Zhang J, Sadeghi R, Dahal A, O Brien K, et al. Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 3
  • 染色质免疫沉淀 ; 小鼠
  • 免疫印迹; 小鼠; 1:2000; 图 1
Walia M, Ho P, Taylor S, Ng A, Gupte A, Chalk A, et al. Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Park S, Lee J, Herbst R, Koo J. GSK-3? Is a Novel Target of CREB and CREB-GSK-3? Signaling Participates in Cell Viability in Lung Cancer. PLoS ONE. 2016;11:e0153075 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 10a
Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 表 1
  • 免疫印迹; 小鼠; 表 1
Papadopoulos D, Dietze R, Shihan M, Kirch U, Scheiner Bobis G. Dehydroepiandrosterone Sulfate Stimulates Expression of Blood-Testis-Barrier Proteins Claudin-3 and -5 and Tight Junction Formation via a Gnα11-Coupled Receptor in Sertoli Cells. PLoS ONE. 2016;11:e0150143 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
  • 免疫印迹; 小鼠; 图 3
  • 免疫印迹; 人类
Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Bian Y, Yang L, Wang Z, Wang Q, Zeng L, Xu G. Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice. Neural Plast. 2015;2015:627837 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 表 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4a
Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Brai E, Marathe S, Astori S, Fredj N, Perry E, Lamy C, et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015;9:447 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4
Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 8
E L, Swerdlow R. Lactate's effect on human neuroblastoma cell bioenergetic fluxes. Biochem Pharmacol. 2016;99:88-100 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Wang Y, Zhang Y, Hu W, Xie S, Gong C, Iqbal K, et al. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015;5:15709 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 5e
  • EMSA; 小鼠; 图 5d
  • 免疫沉淀; 小鼠; 图 5c
  • 免疫印迹; 小鼠; 图 4d
Zhang Y, Li W, Zhu M, Li Y, Xu Z, Zuo B. FHL3 differentially regulates the expression of MyHC isoforms through interactions with MyoD and pCREB. Cell Signal. 2016;28:60-73 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 5
  • 免疫印迹; 小鼠; 图 5
Yang L, McKnight G. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nat Commun. 2015;6:8237 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Lee N, Kwon J, Kim Y, Kim S, Park S, Xu W, et al. Vaccinia-related kinase 1 promotes hepatocellular carcinoma by controlling the levels of cell cycle regulators associated with G1/S transition. Oncotarget. 2015;6:30130-48 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Kim K, Byeon G, Kim H, Baek S, Shin S, Koo S. Mechanical Antiallodynic Effect of Intrathecal Nefopam in a Rat Neuropathic Pain Model. J Korean Med Sci. 2015;30:1189-96 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Rodríguez Seoane C, Ramos A, Korth C, Requena J. DISC1 regulates expression of the neurotrophin VGF through the PI3K/AKT/CREB pathway. J Neurochem. 2015;135:598-605 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5
Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6
Bhushan S, Tchatalbachev S, Lu Y, Fröhlich S, Fijak M, Vijayan V, et al. Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol. 2015;194:5455-64 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Orr A, Hsiao E, Wang M, Ho K, Kim D, Wang X, et al. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015;18:423-34 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Sadegh M, Ekman M, Krawczyk K, Svensson D, Göransson O, Dahan D, et al. Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability. PLoS ONE. 2015;10:e0116784 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Subbanna S, Nagre N, Umapathy N, Pace B, Basavarajappa B. Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. Int J Neuropsychopharmacol. 2014;18: pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 s7g
  • 免疫细胞化学; 人类; 图 s7g
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50
  • 免疫印迹; 小鼠; 1:100
Lauretti E, di Meco A, Chu J, Praticò D. Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor. Neurobiol Aging. 2015;36:812-20 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 5
  • 免疫印迹; 小鼠; 1:1000; 图 5
Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
  • 免疫印迹; 人类; 图 3
  • 免疫印迹; 犬; 图 3
Noguchi S, Kumazaki M, Mori T, Baba K, Okuda M, Mizuno T, et al. Analysis of microRNA-203 function in CREB/MITF/RAB27a pathway: comparison between canine and human melanoma cells. Vet Comp Oncol. 2016;14:384-394 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Leung C, Yeung T, Yip K, Pradeep S, Balasubramanian L, Liu J, et al. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014;5:5092 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2b
Chu Y, Gómez Rosso L, Huang P, Wang Z, Xu Y, Yao X, et al. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. 2014;24:1250-65 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Moody S, Schinzel A, Singh S, Izzo F, Strickland M, Luo L, et al. PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling. Oncogene. 2015;34:2061-71 pubmed 出版商
  • 免疫印迹; 大鼠; 图 e3
Madiraju A, Erion D, Rahimi Y, Zhang X, Braddock D, Albright R, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 2014;510:542-6 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 4
  • 免疫印迹; 大鼠; 1:1000; 图 3a
Chen L, Tiong C, Tsai C, Liao W, Yang S, Youn S, et al. Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency. Brain Struct Funct. 2015;220:663-76 pubmed 出版商
Xing L, Esau C, Trudeau V. Direct Regulation of Aromatase B Expression by 17β-Estradiol and Dopamine D1 Receptor Agonist in Adult Radial Glial Cells. Front Neurosci. 2015;9:504 pubmed 出版商
Xing L, McDonald H, Da Fonte D, Gutierrez Villagomez J, Trudeau V. Dopamine D1 receptor activation regulates the expression of the estrogen synthesis gene aromatase B in radial glial cells. Front Neurosci. 2015;9:310 pubmed 出版商
Akkerman S, Prickaerts J, Bruder A, Wolfs K, De Vry J, Vanmierlo T, et al. PDE5 inhibition improves object memory in standard housed rats but not in rats housed in an enriched environment: implications for memory models?. PLoS ONE. 2014;9:e111692 pubmed 出版商
Musazzi L, Seguini M, Mallei A, Treccani G, Pelizzari M, Tornese P, et al. Time-dependent activation of MAPK/Erk1/2 and Akt/GSK3 cascades: modulation by agomelatine. BMC Neurosci. 2014;15:119 pubmed 出版商
Li B, Jie W, Huang L, Wei P, Li S, Luo Z, et al. Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling. Nat Neurosci. 2014;17:1055-63 pubmed 出版商
Chen L, Dai J, Wang Z, Zhang H, Huang Y, Zhao Y. Ginseng Total Saponins Reverse Corticosterone-Induced Changes in Depression-Like Behavior and Hippocampal Plasticity-Related Proteins by Interfering with GSK-3 ? -CREB Signaling Pathway. Evid Based Complement Alternat Med. 2014;2014:506735 pubmed 出版商
Pérez Gómez A, Tasker R. Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices. BMC Neurosci. 2013;14:72 pubmed 出版商
Heimovics S, Prior N, Maddison C, Soma K. Rapid and widespread effects of 17?-estradiol on intracellular signaling in the male songbird brain: a seasonal comparison. Endocrinology. 2012;153:1364-76 pubmed 出版商
Härmä V, Knuuttila M, Virtanen J, Mirtti T, Kohonen P, Kovanen P, et al. Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models. Oncogene. 2012;31:2075-89 pubmed 出版商
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