产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
p53抗体
目录 :
9282
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, brown rat
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, reverse phase protein lysate microarray, 其他, 免疫印迹基因敲除验证
文章摘录数: 40
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 11
Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed 出版商
  • 免疫印迹; 人类
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5e
Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya M, Wang X, et al. O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis. J Clin Invest. 2018;128:4924-4937 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫沉淀; 人类; 1:200; 图 3a, 3b
Mai W, Gosa L, Daniëls V, Ta L, Tsang J, Higgins B, et al. Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Nat Med. 2017;23:1342-1351 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • 免疫印迹; 小鼠; 图 EV1C-E
Hui X, Zhang M, Gu P, Li K, Gao Y, Wu D, et al. Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue. EMBO Rep. 2017;18:645-657 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Obeid S, Wankell M, Charrez B, Sternberg J, Kreuter R, Esmaili S, et al. Adiponectin confers protection from acute colitis and restricts a B cell immune response. J Biol Chem. 2017;292:6569-6582 pubmed 出版商
  • 免疫印迹; 人类
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 6b
  • 免疫印迹; 人类; 图 6c
Cholewa B, Ndiaye M, Huang W, Liu X, Ahmad N. Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo. Cancer Lett. 2017;385:179-187 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Dey K, Bharti R, Dey G, Pal I, Rajesh Y, Chavan S, et al. S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway. Cancer Gene Ther. 2016;23:382-391 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
  • 免疫印迹; 人类; 1:200; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 人类; 图 s7a
Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed
  • 免疫印迹; 人类; 图 2
Surtees R, Dowall S, Shaw A, Armstrong S, Hewson R, Carroll M, et al. Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle. J Virol. 2016;90:9305-16 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  • 免疫印迹; 小鼠; 图 s4a
Lao T, Jiang Z, Yun J, Qiu W, Guo F, Huang C, et al. Hhip haploinsufficiency sensitizes mice to age-related emphysema. Proc Natl Acad Sci U S A. 2016;113:E4681-7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7
Edmondson R, Adcock A, Yang L. Influence of Matrices on 3D-Cultured Prostate Cancer Cells' Drug Response and Expression of Drug-Action Associated Proteins. PLoS ONE. 2016;11:e0158116 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 4
Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 4
  • 免疫印迹; 人类; 1:1000; 图 3a
Liu B, Shi Y, Peng W, Zhang Q, Liu J, Chen N, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-? signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016;14:159-64 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, et al. HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. J Biol Chem. 2016;291:12688-705 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 s5
  • 免疫印迹; 人类; 1:500; 图 4
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed 出版商
  • 免疫印迹; 人类; 图 1i
Liu X, Tan Y, Zhang C, Zhang Y, Zhang L, Ren P, et al. NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2. EMBO Rep. 2016;17:349-66 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5d
Bai G, Smolka M, Schimenti J. Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS Genet. 2016;12:e1005787 pubmed 出版商
  • 免疫印迹; 人类; 图 5A
Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed 出版商
  • 免疫印迹; 人类; 图 1k
Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, et al. Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival. Oncogene. 2016;35:2441-52 pubmed 出版商
Hsu J, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, et al. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018;23:700-713.e6 pubmed 出版商
Liu J, Ben Q, Lu E, He X, Yang X, Ma J, et al. Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer. Cell Death Dis. 2018;9:168 pubmed 出版商
Jangi M, Fleet C, Cullen P, Gupta S, Mekhoubad S, Chiao E, et al. SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage. Proc Natl Acad Sci U S A. 2017;114:E2347-E2356 pubmed 出版商
Deng Z, Liu X, Jin J, Xu H, Gao Q, Wang Y, et al. Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation. Int J Biol Sci. 2016;12:1298-1308 pubmed
Pradhan S, Mahajan D, Kaur P, Pandey N, Sharma C, Srivastava T. Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells. Oncotarget. 2016;7:71841-71855 pubmed 出版商
Nagaria P, Robert C, Park T, Huo J, Zambidis E, Rassool F. High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional Signature. Stem Cells Int. 2016;2016:3826249 pubmed 出版商
Moureau S, Luessing J, Harte E, Voisin M, Lowndes N. A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining. Open Biol. 2016;6: pubmed
Du Y, Shang B, Sheng W, Zhang S, Li Y, Miao Q, et al. A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer. Oncotarget. 2016;7:58418-58434 pubmed 出版商
Fransson A, Glaessgen D, Alfredsson J, Wiman K, Bajalica Lagercrantz S, Mohell N. Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancer. J Ovarian Res. 2016;9:27 pubmed 出版商
Lupini L, Pepe F, Ferracin M, Braconi C, Callegari E, Pagotto S, et al. Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma. Oncotarget. 2016;7:31361-71 pubmed 出版商
Feng F, Zhang Y, Kothari V, Evans J, Jackson W, Chen W, et al. MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner. Neoplasia. 2016;18:213-22 pubmed 出版商
Wang P, Liu B, Xia Y, Pan C, Ma T, Chen Y. Long non-coding RNA-Low Expression in Tumor inhibits the invasion and metastasis of esophageal squamous cell carcinoma by regulating p53 expression. Mol Med Rep. 2016;13:3074-82 pubmed 出版商
Bargiela Iparraguirre J, Prado Marchal L, Fernandez Fuente M, Gutierrez González A, Moreno Rubio J, Muñoz Fernandez M, et al. CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response. Sci Rep. 2016;6:21519 pubmed 出版商
产品信息
SKU号 :
9282S
产品名称 :
p53抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, R, Mk
应用 :
染色质免疫沉淀
产品种类 :
细胞周期/节律点控制
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
53
宿主 :
靶标 :
p53
最初蛋白 :
p53
别名 :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。