产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化p53(Ser15)(16G8)小鼠单克隆抗体
目录 :
9286
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
16G8
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, proximity ligation assay
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 4a
Callender L, Carroll E, Bober E, Akbar A, Solito E, Henson S. Mitochondrial mass governs the extent of human T cell senescence. Aging Cell. 2020;19:e13067 pubmed 出版商
  • 免疫印迹; 人类
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 s1a
Kucab J, Zou X, Morganella S, Joel M, Nanda A, Nagy E, et al. A Compendium of Mutational Signatures of Environmental Agents. Cell. 2019;177:821-836.e16 pubmed 出版商
  • 免疫印迹; 犬; 表 1
Bulldan A, Shihan M, Goericke Pesch S, Scheiner Bobis G. Signaling events associated with gonadotropin releasing hormone-agonist-induced hormonal castration and its reversal in canines. Mol Reprod Dev. 2016;83:1092-1101 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Zhang Y, Zhang Y, Zhong C, Xiao F. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci Rep. 2016;6:34578 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Skrdlant L, Stark J, Lin R. Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C. BMC Mol Biol. 2016;17:18 pubmed 出版商
  • proximity ligation assay; 人类; 图 3
Hampp S, Kiessling T, Buechle K, Mansilla S, Thomale J, Rall M, et al. DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progression. Proc Natl Acad Sci U S A. 2016;113:E4311-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  • 免疫印迹; 人类; 1:1000; 图 4c, d
Xiong Y, Su H, Lv P, Ma Y, Wang S, Miao H, et al. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. Oncotarget. 2015;6:35625-35 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7a
Bi J, Huang A, Liu T, Zhang T, Ma H. Expression of DNA damage checkpoint 53BP1 is correlated with prognosis, cell proliferation and apoptosis in colorectal cancer. Int J Clin Exp Pathol. 2015;8:6070-82 pubmed
  • 免疫印迹; 小鼠; 图 6a
Lebrun Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Kotipatruni R, Ren X, Thotala D, Jaboin J. NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells. Oncotarget. 2015;6:17594-604 pubmed
  • 免疫印迹; 大鼠
  • 免疫细胞化学; 人类
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3h
Pilar Valdecantos M, Prieto Hontoria P, Pardo V, Módol T, Santamaría B, Weber M, et al. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. Free Radic Biol Med. 2015;84:263-278 pubmed 出版商
  • 免疫印迹; 人类
Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed 出版商
  • 免疫印迹; 人类
Hsieh W, Huang Y, Wang T, Ming Y, Tsai C, Pang J. IFI27, a novel epidermal growth factor-stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes. Cell Prolif. 2015;48:187-97 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Gao R, Liu Y, Silva Fernandes A, Fang X, Paulucci Holthauzen A, Chatterjee A, et al. Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3. PLoS Genet. 2015;11:e1004834 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4B
Xia J, Chen S, Lv Y, Lu L, Hu W, Zhou Y. ZGDHu-1 induces Gâ‚‚/M phase arrest and apoptosis in Kasumi-1 cells. Mol Med Rep. 2015;11:3398-404 pubmed 出版商
  • 免疫印迹; 人类
Kawasumi M, Bradner J, Tolliday N, Thibodeau R, Sloan H, Brummond K, et al. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. Cancer Res. 2014;74:7534-45 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hühn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Patwardhan G, Hosain S, Liu D, Khiste S, Zhao Y, Bielawski J, et al. Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells. Biochim Biophys Acta. 2014;1841:1571-80 pubmed 出版商
  • 免疫印迹; 人类
Lee J, Guo Z, Myler L, Zheng S, Paull T. Direct activation of ATM by resveratrol under oxidizing conditions. PLoS ONE. 2014;9:e97969 pubmed 出版商
  • 免疫印迹; 人类
Du Y, Teng X, Wang N, Zhang X, Chen J, Ding P, et al. NF-?B and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem. 2014;289:2711-24 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商
  • 免疫印迹; 人类
Zakharchenko O, Cojoc M, Dubrovska A, Souchelnytskyi S. A role of TGFß1 dependent 14-3-3σ phosphorylation at Ser69 and Ser74 in the regulation of gene transcription, stemness and radioresistance. PLoS ONE. 2013;8:e65163 pubmed 出版商
  • 免疫印迹; 人类
Wu L, Shao L, Li M, Zheng J, Wang J, Feng W, et al. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks. Radiat Res. 2013;179:160-70 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Zhang T, Penicud K, Bruhn C, Loizou J, Kanu N, Wang Z, et al. Competition between NBS1 and ATMIN controls ATM signaling pathway choice. Cell Rep. 2012;2:1498-504 pubmed 出版商
  • 免疫组化; 小鼠
Martin L, Liu Z, Chen K, Price A, Pan Y, Swaby J, et al. Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. J Comp Neurol. 2007;500:20-46 pubmed
Zhang H, Zhan C, Ke J, Xue Z, Zhang A, Xu K, et al. EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. Oncotarget. 2016;7:3367-78 pubmed 出版商
Hattori H, Janky R, Nietfeld W, Aerts S, Madan Babu M, Venkitaraman A. p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response. Cell Cycle. 2014;13:2572-86 pubmed 出版商
Maya Mendoza A, Merchut Maya J, Bartkova J, Bartek J, Streuli C, Jackson D. Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state. Cell Death Dis. 2014;5:e1351 pubmed 出版商
Chen J, Li L, Su J, Li B, Chen T, Wong Y. Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. PLoS ONE. 2014;9:e101277 pubmed 出版商
Li Y, Gao J, Zhong Z, Hoi P, Lee S, Wang Y. Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Pharmacol Rep. 2013;65:700-9 pubmed
Wang L, Xiang S, Williams K, Dong H, Bai W, Nicosia S, et al. Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells. PLoS ONE. 2012;7:e44265 pubmed 出版商
Ye Y, Xiao Y, Wang W, Gao J, Yearsley K, Yan Q, et al. Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis. Oncotarget. 2012;3:475-89 pubmed
Chae H, Lee M, Broxmeyer H. 5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation. Stem Cells. 2012;30:140-9 pubmed 出版商
产品信息
SKU号 :
9286S
产品名称 :
磷酸化p53(Ser15)(16G8)小鼠单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H
应用 :
流式细胞仪
产品种类 :
细胞周期/节律点控制
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
53
宿主 :
小鼠
靶标 :
p53(Ser15)磷酸盐
最初蛋白 :
p53
别名 :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。