产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
PARP(46D11)兔单克隆抗体
目录 :
9532
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
46D11
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, reverse phase protein lysate microarray, 其他, 免疫印迹基因敲除验证, 免疫细胞化学基因敲除验证
文章摘录数: 230
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 3e
Keane L, Cheray M, Saidi D, Kirby C, Friess L, González Rodríguez P, et al. Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas. Neurooncol Adv. 2021;3:vdab096 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Yan D, Li X, Yang Q, Huang Q, Yao L, Zhang P, et al. Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30. Cell Death Discov. 2021;7:211 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, et al. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation. Nat Commun. 2021;12:3651 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed 出版商
  • 免疫印迹; 人类; 图 4c, 4e
Chen X, Ma W, Yao Y, Zhang Q, Li J, Wu X, et al. Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways. Cell Death Dis. 2021;12:425 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Ditano J, Donahue K, Tafe L, McCleery C, Eastman A. Sensitivity of cells to ATR and CHK1 inhibitors requires hyperactivation of CDK2 rather than endogenous replication stress or ATM dysfunction. Sci Rep. 2021;11:7077 pubmed 出版商
  • 免疫细胞化学基因敲除验证; 人类; 1:1000; 图 2a
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 s3c
  • 免疫组化-石蜡切片; 人类; 图 4a
  • 免疫细胞化学; 人类; 1:1000; 图 2a
  • 免疫印迹; 人类; 1:1000; 图 s3c
Riad A, Gitto S, Lee H, Winters H, Martorano P, Hsieh C, et al. PARP Theranostic Auger Emitters Are Cytotoxic in BRCA Mutant Ovarian Cancer and Viable Tumors from Ovarian Cancer Patients Enable Ex-Vivo Screening of Tumor Response. Molecules. 2020;25: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Carullo G, Mazzotta S, Koch A, Hartmann K, Friedrich O, Gilbert D, et al. New Oleoyl Hybrids of Natural Antioxidants: Synthesis and In Vitro Evaluation as Inducers of Apoptosis in Colorectal Cancer Cells. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 6f
Moses N, Zhang M, Wu J, Hu C, Xiang S, Geng X, et al. HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Cheng C, Wooten J, Gibbs Z, McGlynn K, Mishra P, Whitehurst A. Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5c
He S, Fang X, Xia X, Hou T, Zhang T. Targeting CDK9: A novel biomarker in the treatment of endometrial cancer. Oncol Rep. 2020;44:1929-1938 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
González Rodríguez P, Cheray M, Füllgrabe J, Salli M, Engskog Vlachos P, Keane L, et al. The DNA methyltransferase DNMT3A contributes to autophagy long-term memory. Autophagy. 2020;:1-19 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Gu J, Zhang Y, Wang X, Xiang J, Deng S, Wu D, et al. Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway. BMC Complement Med Ther. 2020;20:214 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Zhang H, Qi L, Du Y, Huang L, Braun F, Kogiso M, et al. Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7a
Arai S, Varkaris A, Nouri M, Chen S, Xie L, Balk S. MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Feng Y, Mischler W, Gurung A, Kavanagh T, Androsov G, Sadow P, et al. Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis. Cancer Res. 2020;80:2751-2763 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d
Zhang J, Huang J, Zhang Y, Zhang X, Zhao L, Li C, et al. Microtubule associated protein 9 inhibits liver tumorigenesis by suppressing ERCC3. EBioMedicine. 2020;53:102701 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed 出版商
  • 免疫印迹; 人类; 图 4g
Liu Q, Borcherding N, Shao P, Maina P, Zhang W, Qi H. Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance. EBioMedicine. 2020;51:102612 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Chen X, Xiong X, Cui D, Yang F, Wei D, Li H, et al. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020;39:1557-1571 pubmed 出版商
  • 免疫印迹; 人类; 图 s5a
Yukawa M, Jagannathan S, Vallabh S, Kartashov A, Chen X, Weirauch M, et al. AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation. J Exp Med. 2020;217: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6e
Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2g
Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, et al. GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling. Nat Commun. 2019;10:3882 pubmed 出版商
  • 免疫印迹; 人类; 图 7b
Guan J, Zhou W, Hafner M, Blake R, Chalouni C, Chen I, et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility. Cell. 2019;178:949-963.e18 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2a
Hernández Alvarez M, Sebastian D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, et al. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 2019;177:881-895.e17 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Shi K, Yin X, Cai M, Yan Y, Jia C, Ma P, et al. PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Singh R, Peng S, Viswanath P, Sambandam V, Shen L, Rao X, et al. Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis. EMBO Mol Med. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2d
He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Liu X, Chen H, Hou Y, Ma X, Ye M, Huang R, et al. Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway. Int J Oncol. 2019;54:1466-1480 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Chen M, Du Y, Sun L, Hsu J, Wang Y, Gao Y, et al. H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism. J Biol Chem. 2019;294:8516-8528 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Luo H, Jing B, Xia Y, Zhang Y, Hu M, Cai H, et al. WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia. Cancer Cell Int. 2019;19:56 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Gennaro V, Wedegaertner H, McMahon S. Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC. BMC Cancer. 2019;19:258 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Yuan Z, Zhang H, Hasnat M, Ding J, Chen X, Liang P, et al. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology. 2019;414:45-56 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5f
Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Serebryannyy L, Misteli T. HiPLA: High-throughput imaging proximity ligation assay. Methods. 2019;157:80-87 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1a
Jeon Y, Kim T, Park D, Nuovo G, Rhee S, Joshi P, et al. miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC. Nat Commun. 2018;9:5110 pubmed 出版商
  • 免疫印迹; 人类; 图 s15a
Zhao D, Kim Y, Jeong S, Greenson J, Chaudhry M, Hoepting M, et al. Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease. J Clin Invest. 2018;128:4970-4979 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4e
Lin X, Cui M, Xu D, Hong D, Xia Y, Xu C, et al. Liver-specific deletion of Eva1a/Tmem166 aggravates acute liver injury by impairing autophagy. Cell Death Dis. 2018;9:768 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1j
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Zhang X, Zhuang R, Wu H, Chen J, Wang F, Li G, et al. A novel role of endocan in alleviating LPS-induced acute lung injury. Life Sci. 2018;202:89-97 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Sagulenko V, Vitak N, Vajjhala P, Vince J, Stacey K. Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8. J Mol Biol. 2018;430:238-247 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4c
Miles M, Hawkins C. Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. Cell Death Dis. 2017;8:e3062 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Zhao Z, Jia Q, Wu M, Xie X, Wang Y, Song G, et al. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018;24:130-144 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1h
Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, et al. Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway. Sci Rep. 2017;7:11776 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed 出版商
  • 免疫印迹; 人类; 图 s9b
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a, 2b
Xu S, Yang Z, Fan Y, Guan B, Jia J, Gao Y, et al. Curcumin enhances temsirolimus-induced apoptosis in human renal carcinoma cells through upregulation of YAP/p53. Oncol Lett. 2016;12:4999-5006 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
Chang V, Tsai Y, Tsai Y, Peng S, Chen S, Chang T, et al. Krüpple-like factor 10 regulates radio-sensitivity of pancreatic cancer via UV radiation resistance-associated gene. Radiother Oncol. 2017;122:476-484 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Brasacchio D, Alsop A, Noori T, Lufti M, Iyer S, Simpson K, et al. Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization. Cell Death Differ. 2017;24:961-970 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Guicciardi M, Krishnan A, Bronk S, Hirsova P, Griffith T, Gores G. Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice. Cell Death Dis. 2017;8:e2535 pubmed 出版商
  • 免疫印迹; 人类; 图 3a, 1e
  • 免疫印迹; 小鼠; 图 1d, 3c
Choi Y, Shembade N, Parvatiyar K, Balachandran S, Harhaj E. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017;37: pubmed 出版商
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Guan S, Zhao Y, Lu J, Yu Y, Sun W, Mao X, et al. Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis. Oncotarget. 2016;7:75914-75925 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Shi Y, Yu Y, Wang Z, Wang H, Bieerkehazhi S, Zhao Y, et al. Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells. Oncotarget. 2016;7:73697-73710 pubmed 出版商
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Tavana O, Li D, Dai C, Lopez G, Banerjee D, Kon N, et al. HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma. Nat Med. 2016;22:1180-1186 pubmed 出版商
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Waters A, Stafman L, Garner E, Mruthyunjayappa S, Stewart J, Mroczek Musulman E, et al. Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells. Transl Oncol. 2016;9:263-73 pubmed 出版商
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Oza J, Ganguly B, Kulkarni A, Ginjala V, Yao M, Ganesan S. A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response. J Biol Chem. 2016;291:22881-22893 pubmed
  • 免疫印迹; 人类; 图 8a
Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Wu J, Lei H, Zhang J, Chen X, Tang C, Wang W, et al. Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation. Oncotarget. 2016;7:58995-59005 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Hogg S, Newbold A, Vervoort S, Cluse L, Martin B, Gregory G, et al. BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members. Mol Cancer Ther. 2016;15:2030-41 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Chen Z, Wang Z, Pang J, Yu Y, Bieerkehazhi S, Lu J, et al. Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. Sci Rep. 2016;6:29090 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Li Q, Guo Y, Chen F, Liu J, Jin P. Stromal cell-derived factor-1 promotes human adipose tissue-derived stem cell survival and chronic wound healing. Exp Ther Med. 2016;12:45-50 pubmed
  • 免疫印迹; 人类; 图 4
Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi A, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:7124-9 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Liu Z, Lam N, Wang E, Virden R, Pawel B, Attiyeh E, et al. Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene. 2017;36:97-109 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Gilmore J, Sardiu M, Groppe B, Thornton J, Liu X, Dayebgadoh G, et al. WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE. 2016;11:e0155492 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Huang Y, Yang X, Xu T, Kong Q, Zhang Y, Shen Y, et al. Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs. Int J Oncol. 2016;49:153-63 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Yalon M, Tuval Kochen L, Castel D, Moshe I, Mazal I, Cohen O, et al. Overcoming Resistance of Cancer Cells to PARP-1 Inhibitors with Three Different Drug Combinations. PLoS ONE. 2016;11:e0155711 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Ribeiro J, Schorl C, Yano N, Romano N, Kim K, Singh R, et al. HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells. J Ovarian Res. 2016;9:28 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Hein A, Post C, Sheinin Y, Lakshmanan I, Natarajan A, Enke C, et al. RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment. Oncogene. 2016;35:6319-6329 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4e
Deng H, Mi M. Resveratrol Attenuates A?25-35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway. Neurochem Res. 2016;41:2367-79 pubmed 出版商
  • reverse phase protein lysate microarray; 小鼠; 图 s1.b,c
Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5b
Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s5
Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Ding M, Bruick R, Yu Y. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling. Nat Cell Biol. 2016;18:319-27 pubmed 出版商
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产品信息
SKU号 :
9532S
产品名称 :
PARP(46D11)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, Mk
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
凋亡
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
116, 89
宿主 :
靶标 :
PARP1 (Asp214, 89 kD) cleaved
最初蛋白 :
多聚(ADP-核糖)聚合酶
别名 :
ADP-ribosyltransferase (NAD+,ADP-ribosyltransferase NAD(+),ADPRT,ADPRT 1,ADPRT1,NAD(+) ADP-ribosyltransferase 1,PARP,PARP-1,PARP1,PPOL,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,pADPRT-1,poly (ADP-ribose) polymerase 1,poly (ADP-ribose) polymerase family, member 1,poly (ADP-ribose) polymerase),poly(ADP-ribose) polymerase,poly(ADP-ribose) synthetase,poly(ADP-ribosyl)transferase
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。