Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商

Nan H, Han L, Ma J, Yang C, Su R, He J. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1684-1692 pubmed 出版商

Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商

Shi J, Bei Y, Kong X, Liu X, Lei Z, Xu T, et al. miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury. Theranostics. 2017;7:664-676 pubmed 出版商

Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed 出版商

Mustachio L, Kawakami M, Lu Y, Rodriguez Canales J, Mino B, Behrens C, et al. The ISG15-specific protease USP18 regulates stability of PTEN. Oncotarget. 2017;8:3-14 pubmed 出版商

Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商

Nip H, Dar A, Saini S, Colden M, Varahram S, Chowdhary H, et al. Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer. Oncotarget. 2016;7:68371-68384 pubmed 出版商

Seneviratne U, Nott A, Bhat V, Ravindra K, Wishnok J, Tsai L, et al. S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration. Proc Natl Acad Sci U S A. 2016;113:4152-7 pubmed 出版商

Creedon H, Balderstone L, Muir M, Balla J, Gómez Cuadrado L, Tracey N, et al. Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer. Dis Model Mech. 2016;9:131-40 pubmed 出版商

Kyathanahalli C, Organ K, Moreci R, Anamthathmakula P, Hassan S, Caritis S, et al. Uterine endoplasmic reticulum stress-unfolded protein response regulation of gestational length is caspase-3 and -7-dependent. Proc Natl Acad Sci U S A. 2015;112:14090-5 pubmed 出版商

Bagulho A, Vilas Boas F, Pena A, Peneda C, Santos F, Jerónimo A, et al. The extracellular matrix modulates H2O2 degradation and redox signaling in endothelial cells. Redox Biol. 2015;6:454-60 pubmed 出版商

Shnitsar I, Bashkurov M, Masson G, Ogunjimi A, Mosessian S, Cabeza E, et al. PTEN regulates cilia through Dishevelled. Nat Commun. 2015;6:8388 pubmed 出版商

Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed 出版商

Chiang C, Uzoma I, Lane D, MemiÅ¡ević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed 出版商

Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, et al. Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med. 2015;7:1048-62 pubmed 出版商

Subathra M, Korrapati M, Howell L, Arthur J, Shayman J, Schnellmann R, et al. Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells. Am J Physiol Renal Physiol. 2015;309:F204-15 pubmed 出版商

Chen H, Huang W, Yang L, Lin C. The PTEN-AKT-mTOR/RICTOR Pathway in Nasal Natural Killer Cell Lymphoma Is Activated by miR-494-3p via PTEN But Inhibited by miR-142-3p via RICTOR. Am J Pathol. 2015;185:1487-99 pubmed 出版商

Yazlovitskaya E, Tseng H, Viquez O, Tu T, Mernaugh G, McKee K, et al. Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015;26:1857-74 pubmed 出版商

Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep. 2015;5:8428 pubmed 出版商

Sadegh M, Ekman M, Krawczyk K, Svensson D, Göransson O, Dahan D, et al. Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability. PLoS ONE. 2015;10:e0116784 pubmed 出版商

Niemeyer B, Parrish J, Spoelstra N, Joyal T, Richer J, Jedlicka P. Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. PLoS ONE. 2015;10:e0116895 pubmed 出版商

Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu Y, Fischman A, et al. Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle. PLoS ONE. 2015;10:e0116633 pubmed 出版商

Roe N, Xu X, Kandadi M, Hu N, Pang J, Weiser Evans M, et al. Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy. Biochim Biophys Acta. 2015;1852:290-8 pubmed 出版商

Shaiken T, Opekun A. Dissecting the cell to nucleus, perinucleus and cytosol. Sci Rep. 2014;4:4923 pubmed 出版商

Beltran P, Calzone F, Mitchell P, Chung Y, Cajulis E, Moody G, et al. Ganitumab (AMG 479) inhibits IGF-II-dependent ovarian cancer growth and potentiates platinum-based chemotherapy. Clin Cancer Res. 2014;20:2947-58 pubmed 出版商

Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed 出版商

Zaytouni T, Tsai P, Hitchcock D, DuBois C, Freinkman E, Lin L, et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017;8:242 pubmed 出版商

González Sánchez A, Jaraíz Rodríguez M, Domínguez Prieto M, Herrero González S, Medina J, Tabernero A. Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes. Oncotarget. 2016;7:49819-49833 pubmed 出版商

Zhang H, Cao H, Xu D, Zhu K. MicroRNA-92a promotes metastasis of nasopharyngeal carcinoma by targeting the PTEN/AKT pathway. Onco Targets Ther. 2016;9:3579-88 pubmed 出版商

Peng X, Giménez Cassina A, Petrus P, Conrad M, Rydén M, Arnér E. Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness. Sci Rep. 2016;6:28080 pubmed 出版商

Softic S, Boucher J, Solheim M, Fujisaka S, Haering M, Homan E, et al. Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. Diabetes. 2016;65:2187-200 pubmed 出版商

Piccolo S, Hoffman L, Conner T, Shrestha G, Cohen A, Marks J, et al. Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. Mol Syst Biol. 2016;12:860 pubmed 出版商

Park K, Yun H, Quang T, Oh H, Lee D, Auh Q, et al. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway. Oncotarget. 2016;7:6960-71 pubmed 出版商

Jin Y, Andrade J, Wickstrom E. Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity. PLoS ONE. 2015;10:e0142574 pubmed 出版商

Man S, Zhu Q, Zhu L, Liu Z, Karki R, Malik A, et al. Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer. Cell. 2015;162:45-58 pubmed 出版商

He Y, Ding J, Lin Y, Li J, Shi Y, Wang J, et al. Gambogenic acid alters chemosensitivity of breast cancer cells to Adriamycin. BMC Complement Altern Med. 2015;15:181 pubmed 出版商

Merkel O, Hamacher F, Griessl R, Grabner L, Schiefer A, Prutsch N, et al. Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation. J Pathol. 2015;236:445-56 pubmed 出版商

Garay T, Kenessey I, Molnár E, Juhász Ã, Réti A, László V, et al. Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells. PLoS ONE. 2015;10:e0117021 pubmed 出版商

Liao Y, Lin T, Chen C, Lin S, Au L. The antileukemia activity of natural product HQ17(3) is possibly associated with downregulation of miR-17-92 cluster. Biomed Res Int. 2014;2014:306718 pubmed 出版商

Wang J, Jenkins S, Lamartiniere C. Cell proliferation and apoptosis in rat mammary glands following combinational exposure to bisphenol A and genistein. BMC Cancer. 2014;14:379 pubmed 出版商

Wiegand K, Hennessy B, Leung S, Wang Y, Ju Z, McGahren M, et al. A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation. BMC Cancer. 2014;14:120 pubmed 出版商

Horak P, Tomasich E, Vanhara P, Kratochvílová K, Anees M, Marhold M, et al. TUSC3 loss alters the ER stress response and accelerates prostate cancer growth in vivo. Sci Rep. 2014;4:3739 pubmed 出版商

Sun Q, Mao S, Li H, Zen K, Zhang C, Li L. Role of miR-17 family in the negative feedback loop of bone morphogenetic protein signaling in neuron. PLoS ONE. 2013;8:e83067 pubmed 出版商

Judson R, Greve T, Parchem R, Blelloch R. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013;20:1227-35 pubmed 出版商

Yentrapalli R, Azimzadeh O, Sriharshan A, Malinowsky K, Merl J, Wojcik A, et al. The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation. PLoS ONE. 2013;8:e70024 pubmed 出版商

Mirantes C, Eritja N, Dosil M, Santacana M, Pallares J, Gatius S, et al. An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias. Dis Model Mech. 2013;6:710-20 pubmed 出版商

Johnsson P, Ackley A, Vidarsdottir L, Lui W, Corcoran M, Grander D, et al. A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nat Struct Mol Biol. 2013;20:440-6 pubmed 出版商

Meyer R, D Alessandro L, Kar S, Kramer B, She B, Kaschek D, et al. Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration. Front Physiol. 2012;3:451 pubmed 出版商

Zaman M, Thamminana S, Shahryari V, Chiyomaru T, Deng G, Saini S, et al. Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer. PLoS ONE. 2012;7:e50203 pubmed 出版商

D Amato N, OSTRANDER J, Bowie M, Sistrunk C, Borowsky A, Cardiff R, et al. Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system. PLoS ONE. 2012;7:e45684 pubmed 出版商

Sawitzky M, Zeissler A, Langhammer M, Bielohuby M, Stock P, Hammon H, et al. Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. PLoS ONE. 2012;7:e39711 pubmed 出版商

Nande R, Di Benedetto A, Aimola P, de Carlo F, Carper M, Claudio C, et al. Targeting a newly established spontaneous feline fibrosarcoma cell line by gene transfer. PLoS ONE. 2012;7:e37743 pubmed 出版商

Tran L, Chang C, Plaisier S, Wu S, Dang J, Mischel P, et al. Determining PTEN functional status by network component deduced transcription factor activities. PLoS ONE. 2012;7:e31053 pubmed 出版商

Singh G, Odriozola L, Guan H, Kennedy C, Chan A. Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line. BMC Cancer. 2011;11:490 pubmed 出版商

Vaidya K, Sanchez J, Kim E, Welch D. Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells. Cancer Lett. 2009;281:100-7 pubmed 出版商