产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
切断的胱氨酸-天冬氨酸蛋白酶3(Asp175)(D3E9)兔单克隆抗体
目录 :
9579
克隆性 :
单克隆
宿主 :
共轭标签 :
未共轭
克隆名称 :
D3E9
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:500; 图 3g
Legrand J, Chan A, La H, Rossello F, Ankö M, Fuller Pace F, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1g
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed 出版商
  • 免疫组化; 小鼠; 图 5c
Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau D, Zavala E, et al. NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. Proc Natl Acad Sci U S A. 2018;115:E1876-E1885 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e6c
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 6c
Hernández I, Torres Peraza J, Santos Galindo M, Ramos Morón E, Fernandez Fernandez M, Pérez Álvarez M, et al. The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease. Acta Neuropathol. 2017;134:839-850 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Sun H, Jiang M, Fu X, Cai Q, Zhang J, Yin Y, et al. Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells. Transl Neurodegener. 2017;6:12 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2e
Barazzuol L, Ju L, Jeggo P. A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biol. 2017;15:e2001264 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:400; 图 11
Pan S, Li S, Hu Y, Zhang H, Liu Y, Jiang H, et al. Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia. Oncotarget. 2016;7:79247-79261 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3b
Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed
  • 免疫组化; 人类; 1:500; 图 4e
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed 出版商
  • 免疫细胞化学; 人类; 图 e2a
Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 4b
Fang W, Yao M, Brummer G, Acevedo D, Alhakamy N, Berkland C, et al. Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment. Oncotarget. 2016;7:49349-49367 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
Huang J, CHEN C, Gu H, Li C, Fu X, Jiang M, et al. Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating GRP78 in SH-SY5Y cells. Cell Biol Int. 2016;40:803-11 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 s3
Rios A, Fu N, Jamieson P, Pal B, Whitehead L, Nicholas K, et al. Essential role for a novel population of binucleated mammary epithelial cells in lactation. Nat Commun. 2016;7:11400 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6g
Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Nakagawa A, Adams C, Huang Y, Hamarneh S, Liu W, Von Alt K, et al. Selective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomains. Sci Rep. 2016;6:20390 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Wang Y, Xu S, Xu W, Yang H, Hu P, Li Y. Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells. Mol Med Rep. 2016;13:1111-8 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 2c
Tronnes A, Koschnitzky J, Daza R, Hitti J, Ramirez J, Hevner R. Effects of Lipopolysaccharide and Progesterone Exposures on Embryonic Cerebral Cortex Development in Mice. Reprod Sci. 2016;23:771-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nat Med. 2015;21:1364-71 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 5
Zaitoun I, Johnson R, Jamali N, Almomani R, Wang S, Sheibani N, et al. Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization. PLoS ONE. 2015;10:e0139994 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed 出版商
  • 免疫印迹; 人类
Kao S, Stankovic K. Transactivation of human osteoprotegerin promoter by GATA-3. Sci Rep. 2015;5:12479 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:300; 图 3a
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed 出版商
  • 免疫组化; 小鼠; 图 2
  • 免疫印迹; 小鼠; 图 2
Sykora P, Misiak M, Wang Y, Ghosh S, Leandro G, Liu D, et al. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res. 2015;43:943-59 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Kocher B, White L, Piwnica Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 5c,5d,6
Jeitany M, Pineda J, Liu Q, Porreca R, Hoffschir F, Desmaze C, et al. A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT). Int J Cancer. 2015;136:1546-58 pubmed 出版商
Nazari M, Serrill J, Wan X, Nguyen M, Anklin C, Gallegos D, et al. New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors. J Med Chem. 2017;60:7850-7862 pubmed 出版商
Barthels C, Ogrinc A, Steyer V, Meier S, Simon F, Wimmer M, et al. CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis. Nat Commun. 2017;8:14715 pubmed 出版商
Chuang C, Greenside P, Rogers Z, Brady J, Yang D, Ma R, et al. Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Nat Med. 2017;23:291-300 pubmed 出版商
Zhao Y, Tu M, Wang W, Qiu J, Yu A, Yu A. Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest. Sci Rep. 2016;6:26611 pubmed 出版商
Kong D, Chen F, Sima N. Inhibition of focal adhesion kinase induces apoptosis in bladder cancer cells via Src and the phosphatidylinositol 3-kinase/Akt pathway. Exp Ther Med. 2015;10:1725-1731 pubmed
Barazzuol L, Rickett N, Ju L, Jeggo P. Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015;128:3597-606 pubmed 出版商
Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed 出版商
Sun S, Sun M, Zhang Y, Cheng C, Waqas M, Yu H, et al. In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period. Front Cell Neurosci. 2014;8:248 pubmed 出版商
Abdi J, Garssen J, Faber J, Redegeld F. Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells. J Nutr Biochem. 2014;25:1254-62 pubmed 出版商
Arboleda Velasquez J, Primo V, Graham M, James A, Manent J, D Amore P. Notch signaling functions in retinal pericyte survival. Invest Ophthalmol Vis Sci. 2014;55:5191-9 pubmed 出版商
Abdi J, Mutis T, Garssen J, Redegeld F. Toll-like receptor (TLR)-1/2 triggering of multiple myeloma cells modulates their adhesion to bone marrow stromal cells and enhances bortezomib-induced apoptosis. PLoS ONE. 2014;9:e96608 pubmed 出版商
Bryce S, Bemis J, Mereness J, Spellman R, Moss J, Dickinson D, et al. Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents. Environ Mol Mutagen. 2014;55:542-55 pubmed 出版商
Migliardi G, Sassi F, Torti D, Galimi F, Zanella E, Buscarino M, et al. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas. Clin Cancer Res. 2012;18:2515-25 pubmed 出版商
产品信息
SKU号 :
9579S
产品名称 :
切断的胱氨酸-天冬氨酸蛋白酶3(Asp175)(D3E9)兔单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, (M, R, Mk, B, Pg)
应用 :
流式细胞仪
产品种类 :
凋亡
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
宿主 :
靶标 :
Casp3(Asp175)切断的
最初蛋白 :
Casp3
别名 :
Apopain,CASP-3,CASP3,CPP-32,CPP32,CPP32B,Caspase-3,Caspase-3 subunit p12,Caspase-3 subunit p17,Cysteine protease CPP32,PARP cleavage protease,Protein Yama,SCA-1,SREBP cleavage activity 1,Yama,caspase 3, apoptosis-related cysteine peptidase,caspase 3, apoptosis-related cysteine protease,procaspase3
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。