产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3抗体
目录 :
9662
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
文章摘录数: 176
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s1j
Zhou Z, He H, Wang K, Shi X, Wang Y, Su Y, et al. Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells. Science. 2020;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3g
  • 免疫印迹; 人类; 1:1000; 图 6g
Liao Y, Zhao J, Bulek K, Tang F, Chen X, Cai G, et al. Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. Nat Commun. 2020;11:900 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 5i
Laukoter S, Beattie R, Pauler F, Amberg N, Nakayama K, Hippenmeyer S. Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development. Nat Commun. 2020;11:195 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Chen X, Xiong X, Cui D, Yang F, Wei D, Li H, et al. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020;39:1557-1571 pubmed 出版商
  • 免疫印迹; 人类; 图 10
Thangaraj K, Balasubramanian B, Park S, Natesan K, Liu W, Manju V. Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells. Biomolecules. 2019;9: pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 5a
McComb S, Chan P, Guinot A, Hartmannsdottir H, Jenni S, Dobay M, et al. Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7. Sci Adv. 2019;5:eaau9433 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 5g
Platel J, Angelova A, Bugeon S, Wallace J, Ganay T, Chudotvorova I, et al. Neuronal integration in the adult mouse olfactory bulb is a non-selective addition process. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5c
Jain A, Agostini L, McCarthy G, Chand S, Ramirez A, Nevler A, et al. Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer. Cancer Res. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 25 ng/ml; 图 4c
Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Krishna Subramanian S, Singer S, Armaka M, Banales J, Hölzer K, Schirmacher P, et al. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Luo H, Jing B, Xia Y, Zhang Y, Hu M, Cai H, et al. WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia. Cancer Cell Int. 2019;19:56 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6q
Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, et al. 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling. Aging Cell. 2019;18:e12951 pubmed 出版商
  • 免疫印迹; 人类; 图 3f
Gennaro V, Wedegaertner H, McMahon S. Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC. BMC Cancer. 2019;19:258 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4b
Zhang J, Sheng J, Dong L, Xu Y, Yu L, Liu Y, et al. Cardiomyocyte-specific loss of RMP causes myocardial dysfunction and heart failure. Cardiovasc Res. 2018;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1g
LeBlanc L, Lee B, Yu A, Kim M, Kambhampati A, Dupont S, et al. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2i
Rivera Reyes A, Ye S, E Marino G, Egolf S, E Ciotti G, Chor S, et al. YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma. Cell Death Dis. 2018;9:1108 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s10
Cuchet Lourenço D, Eletto D, Wu C, Plagnol V, Papapietro O, CURTIS J, et al. Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science. 2018;361:810-813 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Xie H, Wang Y, Zhang H, Fan Q, Dai D, Zhuang L, et al. Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury. J Cell Mol Med. 2018;22:4985-4996 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
Peterson B, Campbell J, Ilkayeva O, Grimsrud P, Hirschey M, Newgard C. Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or ? Cell Metabolism in the Absence of Overnutrition. Cell Rep. 2018;24:209-223.e6 pubmed 出版商
  • 免疫印迹; 人类; 图 s3a
Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3c
Kim J, Shin S, Kang J, Kim J. HX-1171 attenuates pancreatic β-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model. Oncotarget. 2018;9:24260-24271 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Lee C, Hsieh T. Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018;47:16-26 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3h
Kou W, Xu X, Ji S, Chen M, Liu D, Wang K, et al. The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice. Biochem Biophys Res Commun. 2018;497:248-255 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Wang Y, Yin B, Li D, Wang G, Han X, Sun X. GSDME mediates caspase-3-dependent pyroptosis in gastric cancer. Biochem Biophys Res Commun. 2018;495:1418-1425 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Sagulenko V, Vitak N, Vajjhala P, Vince J, Stacey K. Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8. J Mol Biol. 2018;430:238-247 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed 出版商
  • 免疫印迹; 人类; 图 s9b
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5b
Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Li Z, Li D, Choi E, Lapidus R, Zhang L, Huang S, et al. Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells. J Biol Chem. 2017;292:13890-13901 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed 出版商
  • 免疫印迹; 人类; 图 s1d
Shaffer S, Dunagin M, Torborg S, Torre E, Emert B, Krepler C, et al. Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance. Nature. 2017;546:431-435 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 s1d
  • 免疫印迹; 人类; 图 s5e
Wang Y, Gao W, Shi X, Ding J, Liu W, He H, et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature. 2017;547:99-103 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Ando K, PARSONS M, Shah R, Charendoff C, Paris S, Liu P, et al. NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. J Cell Biol. 2017;216:1795-1810 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 6a
Gao Y, Zhuang Z, Gao S, Li X, Zhang Z, Ye Z, et al. Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. Am J Transl Res. 2017;9:887-899 pubmed
  • 免疫印迹; 人类; 图 1a
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4e
Fu S, Xu H, Gu M, Liu C, Wang Q, Wan X, et al. Adiponectin deficiency contributes to the development and progression of benign prostatic hyperplasia in obesity. Sci Rep. 2017;7:43771 pubmed 出版商
  • 免疫印迹; 人类
Kong P, Zhu X, Geng Q, Xia L, Sun X, Chen Y, et al. The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer. Mol Ther. 2017;25:1027-1037 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Iurlaro R, Püschel F, León Annicchiarico C, O Connor H, Martin S, Palou Gramón D, et al. Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 猪; 图 1c
Genovese N, Domeier T, Telugu B, Roberts R. Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells. Sci Rep. 2017;7:41833 pubmed 出版商
  • 免疫印迹; 人类; 图 s2c
Nita I, Hostettler K, Tamo L, Medová M, Bombaci G, Zhong J, et al. Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells. Sci Rep. 2017;7:41901 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
Chang V, Tsai Y, Tsai Y, Peng S, Chen S, Chang T, et al. Krüpple-like factor 10 regulates radio-sensitivity of pancreatic cancer via UV radiation resistance-associated gene. Radiother Oncol. 2017;122:476-484 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6c
Irrera N, Vaccaro M, Bitto A, Pallio G, Pizzino G, Lentini M, et al. BAY 11-7082 inhibits the NF-?B and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis. Clin Sci (Lond). 2017;131:487-498 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 8a
Aksoy P, Meneses P. The Role of DCT in HPV16 Infection of HaCaTs. PLoS ONE. 2017;12:e0170158 pubmed 出版商
  • 免疫印迹; 大鼠; 图 s8
Leow S, Chua S, Venkatachalam G, Shen L, Luo L, Clement M. Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway. Oncotarget. 2017;8:16170-16189 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Dawar S, Lim Y, Puccini J, White M, Thomas P, Bouchier Hayes L, et al. Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene. 2017;36:2704-2714 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Lim S, Hwang S, Yu J, Lim J, Kim H. Lycopene inhibits regulator of calcineurin 1-mediated apoptosis by reducing oxidative stress and down-regulating Nucling in neuronal cells. Mol Nutr Food Res. 2017;61: pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 2a
  • 免疫印迹; 人类; 图 1a
Pu X, Storr S, Zhang Y, Rakha E, Green A, Ellis I, et al. Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival. Apoptosis. 2017;22:357-368 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 表 1
Park K, Luo X, Mooney S, Yungher B, Belin S, Wang C, et al. Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole-rats. J Comp Neurol. 2017;525:380-388 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a, 2b
Xu S, Yang Z, Fan Y, Guan B, Jia J, Gao Y, et al. Curcumin enhances temsirolimus-induced apoptosis in human renal carcinoma cells through upregulation of YAP/p53. Oncol Lett. 2016;12:4999-5006 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 5
Ren Z, Aerts J, Vandenplas H, Wang J, Gorbenko O, Chen J, et al. Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2. Cell Death Dis. 2016;7:e2560 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2g
Polanco M, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, et al. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. Sci Transl Med. 2016;8:370ra181 pubmed 出版商
  • 免疫印迹; 大鼠; 图 7b
Wang F, Jia J, Lal N, Zhang D, Chiu A, Wan A, et al. High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature. Cardiovasc Res. 2016;112:656-668 pubmed
  • 免疫印迹; 人类; 1:500; 图 6b
Zhu X, Wang K, Zhang K, Zhang T, Yin Y, Xu F. Ziyuglycoside I Inhibits the Proliferation of MDA-MB-231 Breast Carcinoma Cells through Inducing p53-Mediated G2/M Cell Cycle Arrest and Intrinsic/Extrinsic Apoptosis. Int J Mol Sci. 2016;17: pubmed
  • 免疫细胞化学; 人类; 图 4c
  • 免疫印迹; 人类; 图 4d
Martínez Castillo M, Bonilla Moreno R, Alemán Lazarini L, Meraz Rios M, Orozco L, Cedillo Barron L, et al. A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe. PLoS ONE. 2016;11:e0165971 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2k
Sun H, Zhang M, Cheng K, Li P, Han S, Li R, et al. Resistance of glioma cells to nutrient-deprived microenvironment can be enhanced by CD133-mediated autophagy. Oncotarget. 2016;7:76238-76249 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Guan S, Zhao Y, Lu J, Yu Y, Sun W, Mao X, et al. Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis. Oncotarget. 2016;7:75914-75925 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1g
Choi Y, Maki T, Mandeville E, Koh S, Hayakawa K, Arai K, et al. Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury. Nat Med. 2016;22:1335-1341 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Shi Y, Yu Y, Wang Z, Wang H, Bieerkehazhi S, Zhao Y, et al. Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells. Oncotarget. 2016;7:73697-73710 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Heulot M, Chevalier N, Puyal J, Margue C, Michel S, Kreis S, et al. The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget. 2016;7:64342-64359 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Twardziok M, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, et al. Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma. PLoS ONE. 2016;11:e0159749 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s15
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5F
Kang M, Park K, Yang J, Lee C, Oh S, Yun J, et al. miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells. PLoS ONE. 2016;11:e0160961 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Ma W, Jiang J, Li M, Wang H, Zhang H, He X, et al. The clinical significance of forkhead box protein A1 and its role in colorectal cancer. Mol Med Rep. 2016;14:2625-31 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2d
Zhang L, Ren F, Zhang X, Wang X, Shi H, Zhou L, et al. Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. Dis Model Mech. 2016;9:799-809 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Wang Y, Wang Y, Li G. TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells. Oncotarget. 2016;7:50937-50951 pubmed 出版商
  • 免疫印迹; 人类; 1:800; 图 6
Liu M, Feng L, Sun P, Liu W, Wu W, Jiang B, et al. A Novel Bufalin Derivative Exhibited Stronger Apoptosis-Inducing Effect than Bufalin in A549 Lung Cancer Cells and Lower Acute Toxicity in Mice. PLoS ONE. 2016;11:e0159789 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  • 免疫印迹; 人类; 1:1000; 图 3
Cheng Y, Huang C, Lee Y, Tien L, Ku W, Chien R, et al. Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016;6:30314 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed 出版商
  • 免疫组化; 大鼠; 1:400; 图 7A
  • 免疫印迹; 大鼠; 1:1000; 图 7B
Fang J, Jia C, Zheng Z, Ye X, Wei B, Huang L, et al. Periprostatic implantation of neural differentiated mesenchymal stem cells restores cavernous nerve injury-mediated erectile dysfunction. Am J Transl Res. 2016;8:2549-61 pubmed
  • 免疫印迹; 人类; 图 4
Chen Z, Wang Z, Pang J, Yu Y, Bieerkehazhi S, Lu J, et al. Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. Sci Rep. 2016;6:29090 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 表 3
Simile M, Latte G, Demartis M, Brozzetti S, Calvisi D, Porcu A, et al. Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease. Oncotarget. 2016;7:49194-49216 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Shen J, Li Z, Li L, Lu L, Xiao Z, Wu W, et al. Vascular-targeted TNF? and IFN? inhibits orthotopic colorectal tumor growth. J Transl Med. 2016;14:187 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Ono H, Basson M, Ito H. P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer. Oncotarget. 2016;7:51301-51310 pubmed 出版商
  • 免疫印迹; 小鼠; 1:400; 图 1c
Ding G, Zhao J, Jiang D. Allicin inhibits oxidative stress-induced mitochondrial dysfunction and apoptosis by promoting PI3K/AKT and CREB/ERK signaling in osteoblast cells. Exp Ther Med. 2016;11:2553-2560 pubmed
  • 免疫印迹; 大鼠; 1:1000; 图 3
Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, et al. Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. Sci Rep. 2016;6:27283 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Onesto E, Colombrita C, Gumina V, Borghi M, Dusi S, Doretti A, et al. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts. Acta Neuropathol Commun. 2016;4:47 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4
Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  • 免疫印迹; 人类; 图 1b
Zheng G, Li N, Jia X, Peng C, Luo L, Deng Y, et al. MYCN-mediated miR-21 overexpression enhances chemo-resistance via targeting CADM1 in tongue cancer. J Mol Med (Berl). 2016;94:1129-1141 pubmed
  • 免疫印迹; 人类; 图 4
Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Slørdahl T, Abdollahi P, Vandsemb E, Rampa C, Misund K, Baranowska K, et al. The phosphatase of regenerating liver-3 (PRL-3) is important for IL-6-mediated survival of myeloma cells. Oncotarget. 2016;7:27295-306 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Wong C, Poulin K, Tong G, Christou C, Kennedy M, Falls T, et al. Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer. PLoS ONE. 2016;11:e0151516 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2i
Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, et al. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways. Mol Med Rep. 2016;13:3009-16 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gilormini M, Malesys C, Armandy E, Manas P, Guy J, Magne N, et al. Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC. Oncotarget. 2016;7:16731-44 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1c
Waldeck K, Cullinane C, Ardley K, Shortt J, Martin B, Tothill R, et al. Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model. Int J Cancer. 2016;139:194-204 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9
Ma Y, Guo H, Zhang L, Tao L, Yin A, Liu Z, et al. Estrogen replacement therapy-induced neuroprotection against brain ischemia-reperfusion injury involves the activation of astrocytes via estrogen receptor β. Sci Rep. 2016;6:21467 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Zhang W, Shi H, Zhang M, Liu B, Mao S, Li L, et al. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation. Int J Biochem Cell Biol. 2016;73:127-136 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4e
Tang Y, Hong Y, Bai H, Wu Q, Chen C, Lang J, et al. Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1. Stem Cells. 2016;34:1527-40 pubmed 出版商
  • 免疫印迹; 人类; 图 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Dos Santos E, Carneiro Lobo T, Aoki M, Levantini E, Bassères D. Aurora kinase targeting in lung cancer reduces KRAS-induced transformation. Mol Cancer. 2016;15:12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1d
Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Audet Walsh Ã, Papadopoli D, Gravel S, Yee T, Bridon G, Caron M, et al. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Rep. 2016;14:920-931 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, et al. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget. 2016;7:9188-221 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Koyani C, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, et al. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016;104:29-41 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3b
Kao S, Soares V, Kristiansen A, Stankovic K. Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear. Aging Cell. 2016;15:301-8 pubmed 出版商
  • 免疫印迹; 小鼠
Villarroel Espíndola F, Tapia C, González Stegmaier R, Concha I, Slebe J. Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells. J Cell Physiol. 2016;231:2142-52 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1
Qiu Z, Sun R, Mo X, Li W. The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth. PLoS ONE. 2016;11:e0147185 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Kitamura A, Nakayama Y, Shibasaki A, Taki A, Yuno S, Takeda K, et al. Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity. Sci Rep. 2016;6:19230 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Ho N, Morrison J, Silva A, Coomber B. The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. Biosci Rep. 2016;36:e00299 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4
Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, et al. Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep. 2016;13:1593-601 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, et al. Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma. Oncotarget. 2016;7:1717-31 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Cataldo A, Cheung D, Balsari A, Tagliabue E, Coppola V, Iorio M, et al. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget. 2016;7:786-97 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Alsafadi S, Tourpin S, Bessoltane N, Salomé Desnoulez S, Vassal G, André F, et al. Nuclear localization of the caspase-3-cleaved form of p73 in anoikis. Oncotarget. 2016;7:12331-43 pubmed 出版商
  • 免疫印迹; 大鼠; 图 4a
Yao K, Wu J, Zhang J, Bo J, Hong Z, Zu H. Protective Effect of DHT on Apoptosis Induced by U18666A via PI3K/Akt Signaling Pathway in C6 Glial Cell Lines. Cell Mol Neurobiol. 2016;36:801-9 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1c
Huang C, Chao C, Lee Y, Lu M, Cheng J, Yang Y, et al. Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability. Mol Neurobiol. 2016;53:2169-88 pubmed 出版商
Piulats J, Kondo J, Endo H, Ono H, Hagihara T, Okuyama H, et al. Promotion of malignant phenotype after disruption of the three-dimensional structure of cultured spheroids from colorectal cancer. Oncotarget. 2018;9:15968-15983 pubmed 出版商
Gallagher E, Zelenko Z, Neel B, Antoniou I, Rajan L, Kase N, et al. Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia. Oncogene. 2017;36:6462-6471 pubmed 出版商
Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, et al. Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK. PLoS Pathog. 2017;13:e1006534 pubmed 出版商
Nyquist M, Corella A, Burns J, Coleman I, Gao S, Tharakan R, et al. Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155. Mol Cancer Res. 2017;15:521-531 pubmed 出版商
Wei W, Sun Z, Shen C, Song H, Zhang X, Qiu Z, et al. Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer. Theranostics. 2017;7:987-1001 pubmed 出版商
Dai K, Huang L, Huang Y, Chen Z, Yang L, Jiang Y. 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model. Front Immunol. 2017;8:320 pubmed 出版商
Zhao L, Zhang B. Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes. Sci Rep. 2017;7:44735 pubmed 出版商
De Cicco P, Panza E, Armogida C, Ercolano G, Taglialatela Scafati O, Shokoohinia Y, et al. The Hydrogen Sulfide Releasing Molecule Acetyl Deacylasadisulfide Inhibits Metastatic Melanoma. Front Pharmacol. 2017;8:65 pubmed 出版商
Xu J, Wu Y, Lu G, Xie S, Ma Z, Chen Z, et al. Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B. Redox Biol. 2017;12:198-207 pubmed 出版商
Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed 出版商
Zhang B, Shi X, Xu G, Kang W, Zhang W, Zhang S, et al. Elevated PRC1 in gastric carcinoma exerts oncogenic function and is targeted by piperlongumine in a p53-dependent manner. J Cell Mol Med. 2017;21:1329-1341 pubmed 出版商
Mazzotta C, Manetti M, Rosa I, Romano E, Blagojevic J, Bellando Randone S, et al. Proangiogenic effects of soluble ?-Klotho on systemic sclerosis dermal microvascular endothelial cells. Arthritis Res Ther. 2017;19:27 pubmed 出版商
Zhang S, Liu Y, Wang F, Qiang J, Liu P, Zhang J, et al. Ilexsaponin A attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. PLoS ONE. 2017;12:e0170984 pubmed 出版商
Shah M, Smolko C, Kinicki S, Chapman Z, Brautigan D, Janes K. Profiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes. Mol Cell Proteomics. 2017;16:S244-S262 pubmed 出版商
Schmukler E, Wolfson E, Elazar Z, Kloog Y, Pinkas Kramarski R. Continuous treatment with FTS confers resistance to apoptosis and affects autophagy. PLoS ONE. 2017;12:e0171351 pubmed 出版商
Kim Y, Tian C, Kim J, Shin B, Choo O, Kim Y, et al. Autophagic flux, a possible mechanism for delayed gentamicin-induced ototoxicity. Sci Rep. 2017;7:41356 pubmed 出版商
Kent L, Bae S, Tsai S, Tang X, Srivastava A, Koivisto C, et al. Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 2017;127:830-842 pubmed 出版商
Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, et al. Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Cell Death Dis. 2017;8:e2570 pubmed 出版商
Porrini V, Sarnico I, Benarese M, Branca C, Mota M, Lanzillotta A, et al. Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation. Int J Mol Sci. 2017;18: pubmed 出版商
Kleinsimon S, Kauczor G, Jaeger S, Eggert A, Seifert G, Delebinski C. ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs. BMC Complement Altern Med. 2017;17:26 pubmed 出版商
Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, et al. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 2017;144:201-210 pubmed 出版商
Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed 出版商
Rossi V, Lispi M, Longobardi S, Mattei M, Di Rella F, Salustri A, et al. LH prevents cisplatin-induced apoptosis in oocytes and preserves female fertility in mouse. Cell Death Differ. 2017;24:72-82 pubmed 出版商
Lefort S, Thuleau A, Kieffer Y, Sirven P, Bieche I, Marangoni E, et al. CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients. Oncogene. 2017;36:1211-1222 pubmed 出版商
Zelenko Z, Gallagher E, Tobin Hess A, Belardi V, Rostoker R, Blank J, et al. Silencing vimentin expression decreases pulmonary metastases in a pre-diabetic mouse model of mammary tumor progression. Oncogene. 2017;36:1394-1403 pubmed 出版商
Das S, Tripathi N, Preet R, Siddharth S, Nayak A, Bharatam P, et al. Quinacrine induces apoptosis in cancer cells by forming a functional bridge between TRAIL-DR5 complex and modulating the mitochondrial intrinsic cascade. Oncotarget. 2017;8:248-267 pubmed 出版商
Li S, Feng T, Guo Y, Yu X, Huang Q, Zhang L, et al. Expression of cancerous inhibitor of protein phosphatase 2A in human triple negative breast cancer correlates with tumor survival, invasion and autophagy. Oncol Lett. 2016;12:5370-5376 pubmed 出版商
Chen J, Yang R, Zhang W, Wang Y. Functions of microRNA-143 in the apoptosis, invasion and migration of nasopharyngeal carcinoma. Exp Ther Med. 2016;12:3749-3755 pubmed 出版商
Kuo W, Lo J, Ho T, Pai P, Chiang S, Chen P, et al. Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death. Cell Death Dis. 2016;7:e2455 pubmed 出版商
Zhang D, Bergsneider M, Wang M, Heaney A. Targeting the ERK pathway for the treatment of Cushing's disease. Oncotarget. 2016;7:69149-69158 pubmed 出版商
Romanelli D, Casartelli M, Cappellozza S, de Eguileor M, Tettamanti G. Roles and regulation of autophagy and apoptosis in the remodelling of the lepidopteran midgut epithelium during metamorphosis. Sci Rep. 2016;6:32939 pubmed 出版商
Fu B, Meng W, Zhao H, Zhang B, Tang H, Zou Y, et al. GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5. Sci Rep. 2016;6:31963 pubmed 出版商
Du Y, Shang B, Sheng W, Zhang S, Li Y, Miao Q, et al. A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer. Oncotarget. 2016;7:58418-58434 pubmed 出版商
Weyhenmeyer B, Noonan J, Würstle M, Lincoln F, Johnston G, Rehm M, et al. Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide. Oncotarget. 2016;7:61295-61311 pubmed 出版商
Jiang P, Zhang P, Mukthavaram R, Nomura N, Pingle S, Teng D, et al. Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells. Oncotarget. 2016;7:57932-57942 pubmed 出版商
Guo W, Dong A, Pan X, Lin X, Lin Y, He M, et al. Role of caspase-10 in the death of acute leukemia cells. Oncol Lett. 2016;12:1623-1629 pubmed
Zhang Y, Mu Q, Zhou Z, Song H, Zhang Y, Wu F, et al. Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction. PLoS ONE. 2016;11:e0158038 pubmed 出版商
Liang T, Zhang Y, Yin S, Gan T, An T, Zhang R, et al. Cardio-protecteffect of qiliqiangxin capsule on left ventricular remodeling, dysfunction and apoptosis in heart failure rats after chronic myocardial infarction. Am J Transl Res. 2016;8:2047-58 pubmed
Carpino G, Nobili V, Renzi A, De Stefanis C, Stronati L, Franchitto A, et al. Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway. PLoS ONE. 2016;11:e0157246 pubmed 出版商
Wang H, Yu Y, Jiang Z, Cao W, Wang Z, Dou J, et al. Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis. Sci Rep. 2016;6:26456 pubmed 出版商
Chen C, Dienhart J, Bolton E. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells. PLoS ONE. 2016;11:e0156145 pubmed 出版商
Hu T, Wei G, Xi M, Yan J, Wu X, Wang Y, et al. Synergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathway. Int J Mol Med. 2016;38:83-94 pubmed 出版商
Coutandin D, Osterburg C, Srivastav R, Sumyk M, Kehrloesser S, Gebel J, et al. Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level. elife. 2016;5: pubmed 出版商
Ding X, Chaiteerakij R, Moser C, Shaleh H, Boakye J, Chen G, et al. Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells. Oncotarget. 2016;7:20080-92 pubmed 出版商
Ram D, Ilyukha V, Volkova T, Buzdin A, Tai A, Smirnova I, et al. Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo. Proc Natl Acad Sci U S A. 2016;113:1606-11 pubmed 出版商
Liu T, Shi Y, Wang E, Zhu T, Zhao Q. AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease. Mol Med Rep. 2016;13:1156-62 pubmed 出版商
产品信息
SKU号 :
9662P
产品名称 :
胱氨酸-天冬氨酸蛋白酶3抗体
规格 :
40微升
Price-(USD) :
123美元
物种x :
H, M, R, Mk
应用 :
免疫组化(石蜡)
产品种类 :
凋亡
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
17, 19, 35
宿主 :
靶标 :
Casp3
最初蛋白 :
Casp3
别名 :
Apopain,CASP-3,CASP3,CPP-32,CPP32,CPP32B,Caspase-3,Caspase-3 subunit p12,Caspase-3 subunit p17,Cysteine protease CPP32,PARP cleavage protease,Protein Yama,SCA-1,SREBP cleavage activity 1,Yama,caspase 3, apoptosis-related cysteine peptidase,caspase 3, apoptosis-related cysteine protease,procaspase3
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。