产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
切断的胱氨酸-天冬氨酸蛋白酶3(Asp175)(5A1E)兔单克隆抗体
目录 :
9664P
规格 :
40微升
价格 :
123美元
克隆性 :
单克隆
宿主 :
反应物种 :
African green monkey, 人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, immunohistochemistry - free floating section
文章摘录数: 153
已发表的文献中的应用方法/种属/稀释度参考文献
  • 免疫印迹; 大鼠; 1:1000; 图 4
Liu L, Wang C, Lin Y, Xi Y, Li H, Shi S, et al. Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Mol Med Rep. 2016;14:111-20 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Gao X, Feng J, He Y, Xu F, Fan X, Huang W, et al. hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep. 2016;6:22999 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Hong A, Tseng Y, Cowley G, Jonas O, Cheah J, Kynnap B, et al. Integrated genetic and pharmacologic interrogation of rare cancers. Nat Commun. 2016;7:11987 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3
Silva S, Levy D, Ruiz J, de Melo T, Isaac C, Fidelis M, et al. Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death. J Steroid Biochem Mol Biol. 2016;: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Meinhardt G, Saleh L, Otti G, Haider S, Velicky P, Fiala C, et al. Wingless ligand 5a is a critical regulator of placental growth and survival. Sci Rep. 2016;6:28127 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 4
Jun S, Jung Y, Suh H, Wang W, Kim M, Oh Y, et al. LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun. 2016;7:10994 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Lin K, Cheng S, Tsai S, Tsai J, Lin C, Cheung C. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, et al. ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 2016;19:53-65 pubmed 出版商
  • 免疫印迹; African green monkey; 图 s4
Ezawa I, Sawai Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, et al. Novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells. Cancer Sci. 2016;107:734-45 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Li Q, Guo Y, Chen F, Liu J, Jin P. Stromal cell-derived factor-1 promotes human adipose tissue-derived stem cell survival and chronic wound healing. Exp Ther Med. 2016;12:45-50 pubmed
  • 免疫印迹; 人类; 图 2
Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
  • 免疫印迹; 小鼠; 图 1
Ashraf M, Schwelberger H, Brendel K, Feurle J, Andrassy J, Kotsch K, et al. Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation. Am J Transplant. 2016;16:808-20 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Barroso-González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 2
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Xiong J, Zhou M, Wang Y, Chen L, Xu W, Wang Y, et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep. 2016;6:34079 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 s8
Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget. 2016;7:15065-92 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2
  • 免疫印迹; 人类; 1:1000; 图 s5
Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Podmirseg S, Jakel H, Ranches G, Kullmann M, Sohm B, Villunger A, et al. Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion. Oncogene. 2016;: pubmed 出版商
  • 免疫印迹; 人类; 图 2
  • 免疫印迹; 大鼠; 图 6
Hesler R, Huang J, Starr M, Treboschi V, Bernanke A, Nixon A, et al. TGF-β-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3. Carcinogenesis. 2016;: pubmed
  • 免疫印迹; 小鼠; 图 7
Pang J, Wu Y, Peng J, Yang P, Kuai L, Qin X, et al. Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: involvement in the modulation of blood-brain barrier integrity. Oncotarget. 2016;: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4f
Ranjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Sci Rep. 2016;6:22787 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5
  • 免疫印迹; 人类; 图 5
Lian Y, Yuan J, Cui Q, Feng Q, Xu M, Bei J, et al. Upregulation of KLHDC4 Predicts a Poor Prognosis in Human Nasopharyngeal Carcinoma. PLoS ONE. 2016;11:e0152820 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300; 图 10
Xue H, Yuan G, Guo X, Liu Q, Zhang J, Gao X, et al. A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway. Autophagy. 2016;12:1129-52 pubmed 出版商
  • 免疫印迹; 人类; 1:400; 图 4
Rotondi S, Modarelli A, Oliva M, Rostomyan L, Sanità P, Ventura L, et al. Expression of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in somatotropinomas: Relationship with Aryl hydrocarbon receptor Interacting Protein (AIP) and in vitro effects of fenofibrate in GH3 cells. Mol Cell Endocrinol. 2016;426:61-72 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Long C, Guo W, Zhou H, Wang J, Wang H, Sun X. Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells. Int J Oncol. 2016;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Wang T, Pan D, Zhou Z, You Y, Jiang C, Zhao X, et al. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathog. 2016;12:e1005662 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 7
  • 免疫印迹; 小鼠; 1:1000; 图 7
Dhar S, Kumar A, Zhang L, Rimando A, Lage J, Lewin J, et al. Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer. Oncotarget. 2016;7:18469-84 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Cheng C, Jiao J, Qian Y, Guo X, Huang J, Dai M, et al. Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells. Mol Med Rep. 2016;13:3763-70 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s3
Chatterjee I, Baruah J, Lurie E, Wary K. Endothelial lipid phosphate phosphatase-3 deficiency that disrupts the endothelial barrier function is a modifier of cardiovascular development. Cardiovasc Res. 2016;: pubmed
  • 免疫印迹; 人类; 1:500; 图 5
Amato K, Wang S, Tan L, Hastings A, Song W, Lovly C, et al. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res. 2016;76:305-18 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 2
Nuccitelli R, Berridge J, Mallon Z, Kreis M, Athos B, Nuccitelli P. Nanoelectroablation of Murine Tumors Triggers a CD8-Dependent Inhibition of Secondary Tumor Growth. PLoS ONE. 2015;10:e0134364 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Kaizuka T, Mizushima N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol Cell Biol. 2015;36:585-95 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Yang B, Zhang M, Gao J, Li J, Fan L, Xiang G, et al. Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer. Oncotarget. 2015;6:37613-25 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 8
Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed 出版商
  • 免疫印迹; 人类; 图 8c
Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Ogura Y, Hindi S, Sato S, Xiong G, Akira S, Kumar A. TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair. Nat Commun. 2015;6:10123 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Bida O, Gidoni M, Ideses D, Efroni S, Ginsberg D. A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel. Oncotarget. 2015;6:27880-90 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Ittig S, Schmutz C, Kasper C, Amstutz M, Schmidt A, Sauteur L, et al. A bacterial type III secretion-based protein delivery tool for broad applications in cell biology. J Cell Biol. 2015;211:913-31 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Hirt C, Papadimitropoulos A, Muraro M, Mele V, Panopoulos E, Cremonesi E, et al. Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo". Biomaterials. 2015;62:138-46 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6d
Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, et al. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons. J Physiol. 2015;593:4373-86 pubmed 出版商
  • 免疫印迹; 人类
Girotti M, Lopes F, Preece N, Niculescu-Duvaz D, Zambon A, Davies L, et al. Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma. Cancer Cell. 2015;27:85-96 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200
Chow H, Dong B, Duron S, Campbell D, Ong C, Hoeflich K, et al. Group I Paks as therapeutic targets in NF2-deficient meningioma. Oncotarget. 2015;6:1981-94 pubmed
  • 免疫组化-石蜡切片; 人类; 1:800
Sarr D, Bracken T, Owino S, Cooper C, Smith G, Nagy T, et al. Differential roles of inflammation and apoptosis in initiation of mid-gestational abortion in malaria-infected C57BL/6 and A/J mice. Placenta. 2015;36:738-49 pubmed 出版商
  • 免疫印迹; 小鼠
Liu L, Zou P, Zheng L, Linarelli L, Amarell S, Passaro A, et al. Tamoxifen reduces fat mass by boosting reactive oxygen species. Cell Death Dis. 2015;6:e1586 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Demel H, Feuerecker B, Piontek G, Seidl C, Blechert B, Pickhard A, et al. Effects of topoisomerase inhibitors that induce DNA damage response on glucose metabolism and PI3K/Akt/mTOR signaling in multiple myeloma cells. Am J Cancer Res. 2015;5:1649-64 pubmed
  • 免疫印迹; 大鼠; 图 6
Bejaoui M, Pantazi E, De Luca V, Panisello A, Folch-Puy E, Hotter G, et al. Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. PLoS ONE. 2015;10:e0134499 pubmed 出版商
  • 免疫印迹; 人类
Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed 出版商
  • 免疫印迹; 小鼠
Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed 出版商
  • 免疫印迹; 人类
Shen X, Sun W, Shi Y, Xing Z, Su X. Altered viral replication and cell responses by inserting microRNA recognition element into PB1 in pandemic influenza A virus (H1N1) 2009. Mediators Inflamm. 2015;2015:976575 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:400; 图 6
Hasan S, Sultana S. Geraniol attenuates 2-acetylaminofluorene induced oxidative stress, inflammation and apoptosis in the liver of wistar rats. Toxicol Mech Methods. 2015;25:559-73 pubmed 出版商
  • 免疫印迹; 人类
Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Somsouk M, Estes J, Deléage C, Dunham R, Albright R, Inadomi J, et al. Gut epithelial barrier and systemic inflammation during chronic HIV infection. AIDS. 2015;29:43-51 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 5
He S, Zhao Z, Yang Y, O'Connell D, Zhang X, Oh S, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nat Commun. 2015;6:7839 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Liu W, Lin Y, Yan X, Ding Y, Wu Y, Chen W, et al. Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression. FASEB J. 2015;29:1113-23 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Szabo N, Da Silva R, Sotocinal S, Zeilhofer H, Mogil J, Kania A. Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity, and nociception. J Neurosci. 2015;35:5233-46 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:1000
Kaneko Y, Ota A, Nakashima A, Nagasaki H, Kodani Y, Mori K, et al. Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G₁ phase and protects them from UV light-induced apoptosis. J Neural Transm (Vienna). 2015;122:187-99 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Bettaieb A, Jiang J, Sasaki Y, Chao T, Kiss Z, Chen X, et al. Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. Gastroenterology. 2015;149:468-80.e10 pubmed 出版商
  • 免疫细胞化学; 小鼠
Yuri S, Nishikawa M, Yanagawa N, Jo O, Yanagawa N. Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor. PLoS ONE. 2015;10:e0129242 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 s8
Klotz L, Norman S, Vieira J, Masters M, Rohling M, Dubé K, et al. Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature. 2015;522:62-7 pubmed
  • 免疫印迹; 小鼠; 1:200; 图 s6
Suzuki D, Sahu R, Leu N, Senoo M. The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development. 2015;142:282-90 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 s2
Liu X, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs R, et al. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nat Commun. 2015;6:8325 pubmed 出版商
  • 免疫印迹; 人类; 1:800; 图  4
Zhang Q, Yu S, Huang X, Tan Y, Zhu C, Wang Y, et al. New insights into the function of Cullin 3 in trophoblast invasion and migration. Reproduction. 2015;150:139-49 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
ErLin S, WenJie W, LiNing W, BingXin L, MingDe L, Yan S, et al. Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell. 2015;26:1947-56 pubmed 出版商
  • 免疫印迹; 人类
Waters A, Stewart J, Atigadda V, Mroczek-Musulman E, Muccio D, Grubbs C, et al. Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma. Mol Cancer Ther. 2015;14:1559-69 pubmed 出版商
  • 免疫印迹; 人类
Seeßle J, Liebisch G, Schmitz G, Stremmel W, Chamulitrat W. Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis. Biochim Biophys Acta. 2015;1851:549-65 pubmed 出版商
  • 免疫组化; 小鼠; 1:2000; 图 7
Pértega-Gomes N, Felisbino S, Massie C, Vizcaíno J, Coelho R, Sandi C, et al. A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy. J Pathol. 2015;236:517-30 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3c
Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, et al. Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis. Sci Rep. 2015;5:13737 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Vong K, Leung C, Behringer R, Kwan K. Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 pubmed 出版商
  • 免疫印迹; 大鼠; 图 8
Matsumoto T, Urushido M, Ide H, Ishihara M, Hamada-Ode K, Shimamura Y, et al. Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury. PLoS ONE. 2015;10:e0126229 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4a
Deutsch M, Graffeo C, Rokosh R, Pansari M, Ochi A, Levie E, et al. Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury. Cell Death Dis. 2015;6:e1759 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Long J, Schoonen P, Graczyk D, O'Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500
Noda K, Mishina Y, Komatsu Y. Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice. Dev Biol. 2015;: pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
  • 免疫组化-石蜡切片; 小鼠; 图 7A
Wang Z, Liu N, Liu K, Zhou G, Gan J, Wang Z, et al. Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis. Autophagy. 2015;11:2358-69 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Jiao L, Inhoffen J, Gan-Schreier H, Tuma-Kellner S, Stremmel W, Sun Z, et al. Deficiency of Group VIA Phospholipase A2 (iPLA2β) Renders Susceptibility for Chemical-Induced Colitis. Dig Dis Sci. 2015;60:3590-602 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Han Y, Lee J, Lee S. Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways. Mol Med Rep. 2015;12:3446-52 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50
Veselá B, Svandová E, Vanden Berghe T, Tucker A, Vandenabeele P, Matalova E. Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue. J Mol Histol. 2015;46:443-55 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:800
Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed 出版商
  • 免疫印迹; 人类
Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Borkham-Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200
Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 免疫印迹; 大鼠
Li J, Xu Z, Jiang L, Mao J, Zeng Z, Fang L, et al. Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury. Kidney Int. 2014;86:86-102 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, et al. p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling. Free Radic Biol Med. 2014;67:292-303 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:200
McGraw H, Culbertson M, Nechiporuk A. Kremen1 restricts Dkk activity during posterior lateral line development in zebrafish. Development. 2014;141:3212-21 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Velicky P, Haider S, Otti G, Fiala C, Pollheimer J, Knöfler M. Notch-dependent RBPJκ inhibits proliferation of human cytotrophoblasts and their differentiation into extravillous trophoblasts. Mol Hum Reprod. 2014;20:756-66 pubmed 出版商
  • 免疫印迹; 人类
Kemp M, Gaddameedhi S, Choi J, Hu J, Sancar A. DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. J Biol Chem. 2014;289:26574-83 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Clave S, Joya X, Salat-Batlle J, Garcia-Algar O, Vall O. Ethanol cytotoxic effect on trophoblast cells. Toxicol Lett. 2014;225:216-21 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:200
Bailey K, Rahimi Balaei M, Mannan A, Del Bigio M, Marzban H. Purkinje cell compartmentation in the cerebellum of the lysosomal Acid phosphatase 2 mutant mouse (nax - naked-ataxia mutant mouse). PLoS ONE. 2014;9:e94327 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Ostapoff K, Cenik B, Wang M, Ye R, Xu X, Nugent D, et al. Neutralizing murine TGFβR2 promotes a differentiated tumor cell phenotype and inhibits pancreatic cancer metastasis. Cancer Res. 2014;74:4996-5007 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Zhu G, Fan Z, Ding M, Mu L, Liang J, Ding Y, et al. DNA damage induces the accumulation of Tiam1 by blocking β-TrCP-dependent degradation. J Biol Chem. 2014;289:15482-94 pubmed 出版商
  • 免疫印迹; 大鼠
Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Ying Y, Kim J, Westphal S, Long K, Padanilam B. Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury. J Am Soc Nephrol. 2014;25:2707-16 pubmed 出版商
  • 免疫印迹; 小鼠
Resch U, Cuapio A, Sturtzel C, Hofer E, de Martin R, Holper-Schichl Y. Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis. J Biol Chem. 2014;289:25088-100 pubmed 出版商
  • 免疫印迹; 人类
Wang C, Wang J, Liu Z, Ma X, Wang X, Jin H, et al. Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma. Carcinogenesis. 2014;35:1500-9 pubmed 出版商
  • 免疫组化; 人类; 1:200
Hassan H, Varney M, Jain S, Weisenburger D, Singh R, Dave B. Disruption of chromosomal locus 1p36 differentially modulates TAp73 and ΔNp73 expression in follicular lymphoma. Leuk Lymphoma. 2014;55:2924-31 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200
Cai L, Wang D, Fisher A, Wang Z. Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells. Biochem Biophys Res Commun. 2014;447:292-8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400
Fernández-Estevez M, Casarejos M, Lopez Sendon J, Garcia Caldentey J, Ruiz C, Gomez A, et al. Trehalose reverses cell malfunction in fibroblasts from normal and Huntington's disease patients caused by proteosome inhibition. PLoS ONE. 2014;9:e90202 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1e
Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen-Zender I, et al. In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells. PLoS ONE. 2014;9:e88071 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7
Kukreja L, Kujoth G, Prolla T, Van Leuven F, Vassar R. Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease. Mol Neurodegener. 2014;9:16 pubmed 出版商
  • 免疫组化; 人类; 1:50
Guo W, Liu R, Bhardwaj G, Yang J, Changou C, Ma A, et al. Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. Cell Death Dis. 2014;5:e1409 pubmed 出版商
  • 免疫印迹; 人类; 1:50-500
O'Brien M, Carbin S, Morrison J, Smith T. Decreased myometrial p160 ROCK-1 expression in obese women at term pregnancy. Reprod Biol Endocrinol. 2013;11:79 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
  • 免疫细胞化学; 人类; 1:100
Kyathanahalli C, Marks J, Nye K, Lao B, Albrecht E, Aberdeen G, et al. Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon. Endocrinology. 2013;154:4873-84 pubmed 出版商
Zhu Y, Cui H, Xia Y, Gan H. RIPK3-Mediated Necroptosis and Apoptosis Contributes to Renal Tubular Cell Progressive Loss and Chronic Kidney Disease Progression in Rats. PLoS ONE. 2016;11:e0156729 pubmed 出版商
AbuSara N, Razavi S, Derwish L, Komatsu Y, Licursi M, Hirasawa K. Restoration of IRF1-dependent anticancer effects by MEK inhibition in human cancer cells. Cancer Lett. 2015;357:575-81 pubmed 出版商
Katkoori V, Basson M, Bond V, Manne U, Bumpers H. Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial‑to‑mesenchymal transition in colon and breast cancers. Oncotarget. 2015;6:27763-77 pubmed 出版商
Bleil J, Maier R, Hempfing A, Schlichting U, Appel H, Sieper J, et al. Histomorphologic and histomorphometric characteristics of zygapophyseal joint remodeling in ankylosing spondylitis. Arthritis Rheumatol. 2014;66:1745-54 pubmed 出版商
Kolokoltsova O, Grant A, Huang C, Smith J, Poussard A, Tian B, et al. RIG-I enhanced interferon independent apoptosis upon Junin virus infection. PLoS ONE. 2014;9:e99610 pubmed 出版商
Youn J, Shim H, Lee J, Ji A, Oh J, Hong N, et al. Detailed pathologic evaluation on endomyocardial biopsy provides long-term prognostic information in patients with acute myocarditis. Cardiovasc Pathol. 2014;23:139-44 pubmed 出版商
Foreman K, Jesse J, Kuo P, Gupta G. Emetine dihydrochloride: a novel therapy for bladder cancer. J Urol. 2014;191:502-9 pubmed 出版商
Aiello V, Moreno-Asso A, Servitja J, Martin M. Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue. Exp Cell Res. 2014;322:236-48 pubmed 出版商
Kash J, Xiao Y, Davis A, Walters K, Chertow D, Easterbrook J, et al. Treatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in mice. Free Radic Biol Med. 2014;67:235-47 pubmed 出版商
Unterlauft J, Claudepierre T, Schmidt M, Müller K, Yafai Y, Wiedemann P, et al. Enhanced survival of retinal ganglion cells is mediated by Müller glial cell-derived PEDF. Exp Eye Res. 2014;127:206-14 pubmed 出版商
Freitas M, Gomes R, Soares B, Artigiani Neto R, Montero E, Martins J. Effects of maternal ischemic preconditioning in the colon of newborn rats submitted to hypoxia-reoxygenation insult. Acta Cir Bras. 2014;29:438-44 pubmed
Murakami T, Takigawa N, Ninomiya T, Ochi N, Yasugi M, Honda Y, et al. Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model. Lung Cancer. 2014;83:30-6 pubmed 出版商
Moros A, Rodriguez V, Saborit-Villarroya I, Montraveta A, Balsas P, Sandy P, et al. Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma. Leukemia. 2014;28:2049-59 pubmed 出版商
Shimizu K, Uematsu A, Imai Y, Sawasaki T. Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion. FEBS Lett. 2014;588:3030-7 pubmed 出版商
Alexeev V, Lash E, Aguillard A, Corsini L, Bitterman A, Ward K, et al. Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound. Mol Cancer Ther. 2014;13:2968-77 pubmed 出版商
Lopez M, Kopec A, Joshi N, Geddings J, Cline H, Towery K, et al. Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. Toxicol Sci. 2014;141:453-64 pubmed 出版商
Qu S, Wang K, Xue H, Wang Y, Wu R, Liu C, et al. Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014;8:311-22 pubmed 出版商
Zur Bruegge J, Hanisch C, Einspanier R, Alter T, Gölz G, Sharbati S. Arcobacter butzleri induces a pro-inflammatory response in THP-1 derived macrophages and has limited ability for intracellular survival. Int J Med Microbiol. 2014;304:1209-17 pubmed 出版商
Kitajima M, Dolmans M, Donnez O, Masuzaki H, Soares M, Donnez J. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil Steril. 2014;101:1031-7 pubmed 出版商
Keitel U, Scheel A, Thomale J, Halpape R, Kaulfuß S, Scheel C, et al. Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation. Oncotarget. 2014;5:11778-91 pubmed
Wang H, Zhang Z, Huang J, Zhang P, Xiong N, Wang T. The contribution of Cdc2 in rotenone-induced G2/M arrest and caspase-3-dependent apoptosis. J Mol Neurosci. 2014;53:31-40 pubmed 出版商
Li Q, Zhang Y, El-Naggar A, Xiong S, Yang P, Jackson J, et al. Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors. Mol Cancer Res. 2014;12:901-11 pubmed 出版商
Moon H, Chon J, Joo J, Kim D, In J, Lee H, et al. FTY720 preserved islet β-cell mass by inhibiting apoptosis and increasing survival of β-cells in db/db mice. Diabetes Metab Res Rev. 2013;29:19-24 pubmed 出版商
Dzieran J, Fabian J, Feng T, Coulouarn C, Ilkavets I, Kyselova A, et al. Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS ONE. 2013;8:e72252 pubmed 出版商
Covy J, Waxman E, Giasson B. Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. J Neurosci Res. 2012;90:2306-16 pubmed 出版商
Vegliante M, Palomero J, Perez-Galan P, Roué G, Castellano G, Navarro A, et al. SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma. Blood. 2013;121:2175-85 pubmed 出版商
Wilk C, Schildberg F, Lauterbach M, Cadeddu R, Fröbel J, Westphal V, et al. The tissue inhibitor of metalloproteinases-1 improves migration and adhesion of hematopoietic stem and progenitor cells. Exp Hematol. 2013;41:823-831.e2 pubmed 出版商
Knudsen A, Kannerup A, Grønbæk H, Dutoit S, Nyengaard J, Funch-Jensen P, et al. Quantitative histological assessment of hepatic ischemia-reperfusion injuries following ischemic pre- and post-conditioning in the rat liver. J Surg Res. 2013;180:e11-20 pubmed 出版商
de Andrea C, Wiweger M, Bovee J, Romeo S, Hogendoorn P. Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation. Virchows Arch. 2012;460:95-102 pubmed 出版商
Bajic D, Commons K, Soriano S. Morphine-enhanced apoptosis in selective brain regions of neonatal rats. Int J Dev Neurosci. 2013;31:258-66 pubmed 出版商
Gao X, Lin J, Ning Q, Gao L, Yao Y, Zhou J, et al. A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells. PLoS ONE. 2013;8:e55481 pubmed 出版商
Liu T, Hou D, Zhao Q, Liu W, Zhen P, Xu J, et al. Phytoestrogen α-Zearalanol attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells. Biomed Res Int. 2013;2013:813450 pubmed 出版商
Shimizu K, Sawasaki T. Nek5, a novel substrate for caspase-3, promotes skeletal muscle differentiation by up-regulating caspase activity. FEBS Lett. 2013;587:2219-25 pubmed 出版商
Heindl M, Händel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, et al. Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome. Gastroenterology. 2012;142:1093-1096.e6 pubmed 出版商
Debrincat M, Josefsson E, James C, Henley K, Ellis S, Lebois M, et al. Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival. Blood. 2012;119:5850-8 pubmed 出版商
Miki H, Uehara N, Kimura A, Sasaki T, Yuri T, Yoshizawa K, et al. Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells. Int J Oncol. 2012;40:1020-8 pubmed 出版商
Rosich L, Xargay-Torrent S, López-Guerra M, Campo E, Colomer D, Roué G. Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma. Clin Cancer Res. 2012;18:5278-89 pubmed 出版商
Brobeil A, Bobrich M, Tag C, Wimmer M. PTPIP51 in protein interactions: regulation and in situ interacting partners. Cell Biochem Biophys. 2012;63:211-22 pubmed 出版商
Emmanouilidou A, Karetsou Z, Tzima E, Kobayashi T, Papamarcaki T. Knockdown of prothymosin α leads to apoptosis and developmental defects in zebrafish embryos. Biochem Cell Biol. 2013;91:325-32 pubmed 出版商
Kreslavsky T, Kim H, Koralov S, Ghitza D, Buch T, Cantor H, et al. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes. J Exp Med. 2013;210:1911-8 pubmed 出版商
Jak M, van Bochove G, Reits E, Kallemeijn W, Tromp J, Umana P, et al. CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101. Blood. 2011;118:5178-88 pubmed 出版商
Stiles J, Amaya C, Pham R, Rowntree R, Lacaze M, Mulne A, et al. Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis. Exp Ther Med. 2012;4:594-604 pubmed
Ohno Y, Nakanishi T, Umigai N, Tsuruma K, Shimazawa M, Hara H. Oral administration of crocetin prevents inner retinal damage induced by N-methyl-D-aspartate in mice. Eur J Pharmacol. 2012;690:84-9 pubmed 出版商
Valentino T, Palmieri D, Vitiello M, Pierantoni G, Fusco A, Fedele M. PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context. Cell Death Dis. 2013;4:e963 pubmed 出版商
Wu M, Wang G, Zhao Z, Liang Y, Wang H, Wu M, et al. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Mol Cancer Ther. 2013;12:1728-37 pubmed 出版商
Cheng A, Jiang S, Fan C, Lo Y, Kuo C, Chen C, et al. Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents. Cancer Lett. 2013;337:218-25 pubmed 出版商
Li Q, He H, Zhang Y, Li X, Guo X, Huo R, et al. Phosphoinositide 3-kinase p110δ mediates estrogen- and FSH-stimulated ovarian follicle growth. Mol Endocrinol. 2013;27:1468-82 pubmed 出版商
产品信息
SKU号 :
9664P
产品名称 :
切断的胱氨酸-天冬氨酸蛋白酶3(Asp175)(5A1E)兔单克隆抗体
规格 :
40微升
Price-(USD) :
123美元
物种x :
H, M, R, Mk, (Dg)
应用 :
流式细胞仪
产品种类 :
凋亡
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
17, 19
宿主 :
靶标 :
Casp3(Asp175)切断的
最初蛋白 :
Casp3
别名 :
Apopain,CASP-3,CASP3,CPP-32,CPP32,CPP32B,Caspase-3,Caspase-3 subunit p12,Caspase-3 subunit p17,Cysteine protease CPP32,PARP cleavage protease,Protein Yama,SCA-1,SREBP cleavage activity 1,Yama,caspase 3, apoptosis-related cysteine peptidase,caspase 3, apoptosis-related cysteine protease,procaspase3
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。