产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化组蛋白H2A.X(Ser139)(20E3)兔单克隆抗体(Alexa Fluor系列荧光染料®488共轭标签)
目录 :
9719
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
AF488
抗原修饰 :
磷酸化
克隆名称 :
20E3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪
文章摘录数: 27
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 2c
Jia Y, Kang X, Tan L, Ren Y, Qu L, Tang J, et al. Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence. Front Physiol. 2021;12:649547 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 e2i
Wilkinson A, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo R, et al. Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. Nature. 2019;: pubmed 出版商
  • 免疫组化; 小鼠; 图 5c
  • 免疫印迹; 小鼠; 图 5a
Hou Y, Lautrup S, Cordonnier S, Wang Y, Croteau D, Zavala E, et al. NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. Proc Natl Acad Sci U S A. 2018;115:E1876-E1885 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50; 图 6C
  • 流式细胞仪; 人类; 1:40; 图 6C
Kostrzak A, Caval V, Escande M, Pliquet E, Thalmensi J, Bestetti T, et al. APOBEC3A intratumoral DNA electroporation in mice. Gene Ther. 2017;24:74-83 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 s1d
Del Bel Belluz L, Guidi R, Pateras I, Levi L, Mihaljevic B, Rouf S, et al. The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection. PLoS Pathog. 2016;12:e1005528 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 4
Jun S, Jung Y, Suh H, Wang W, Kim M, Oh Y, et al. LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun. 2016;7:10994 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50; 图 1
  • 免疫组化; 小鼠; 1:50; 图 1
  • 免疫印迹; 小鼠; 1:5000; 图 1
Liu X, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs R, et al. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nat Commun. 2015;6:8325 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Jang C, Shibata Y, Starmer J, Yee D, Magnuson T. Histone H3.3 maintains genome integrity during mammalian development. Genes Dev. 2015;29:1377-92 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Sykora P, Misiak M, Wang Y, Ghosh S, Leandro G, Liu D, et al. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes. Nucleic Acids Res. 2015;43:943-59 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 2
Tanabe M, Tamura H, Taketani T, Okada M, Lee L, Tamura I, et al. Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice. J Reprod Dev. 2015;61:35-41 pubmed 出版商
  • 流式细胞仪; 人类; 1:50; 图 3i
Greve K, Lindgreen J, Terp M, Pedersen C, Schmidt S, Mollenhauer J, et al. Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability. Mol Oncol. 2015;9:437-49 pubmed 出版商
Oben K, Gachuki B, Alhakeem S, McKenna M, Liang Y, St Clair D, et al. Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1). PLoS ONE. 2017;12:e0169767 pubmed 出版商
Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed 出版商
Kilic Eren M, Tabor V. The role of hypoxia inducible factor-1 alpha in bypassing oncogene-induced senescence. PLoS ONE. 2014;9:e101064 pubmed 出版商
Bais M, Ozdener G, Sonenshein G, Trackman P. Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways. Oncogene. 2015;34:1928-37 pubmed 出版商
Hall M, Telma K, Chang K, Lee T, Madigan J, Lloyd J, et al. Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes. Cancer Res. 2014;74:3913-22 pubmed 出版商
Kubota S, Fukumoto Y, Ishibashi K, Soeda S, Kubota S, Yuki R, et al. Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage. J Biol Chem. 2014;289:5730-46 pubmed 出版商
Nasuno T, Mimaki S, Okamoto M, Esumi H, Tsuchihara K. Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines. Cancer Sci. 2014;105:202-10 pubmed 出版商
Bakkenist C, Czambel R, Clump D, Greenberger J, Beumer J, Schmitz J. Radiation therapy induces the DNA damage response in peripheral blood. Oncotarget. 2013;4:1143-8 pubmed
Sun B, Ross S, Trask O, Carmichael P, Dent M, White A, et al. Assessing dose-dependent differences in DNA-damage, p53 response and genotoxicity for quercetin and curcumin. Toxicol In Vitro. 2013;27:1877-87 pubmed 出版商
Volotskova O, Hawley T, Stepp M, Keidar M. Targeting the cancer cell cycle by cold atmospheric plasma. Sci Rep. 2012;2:636 pubmed 出版商
Hu C, Zhang S, Gao X, Gao X, Xu X, Lv Y, et al. Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response. J Biol Chem. 2012;287:18937-52 pubmed 出版商
Wei S, Xiong M, Zhan D, Liang B, Wang Y, Gutmann D, et al. Ku80 functions as a tumor suppressor in hepatocellular carcinoma by inducing S-phase arrest through a p53-dependent pathway. Carcinogenesis. 2012;33:538-47 pubmed 出版商
Pei X, Dai Y, Youssefian L, Chen S, Bodie W, Takabatake Y, et al. Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2. Blood. 2011;118:5189-200 pubmed 出版商
Negrotto S, Hu Z, Alcazar O, Ng K, Triozzi P, Lindner D, et al. Noncytotoxic differentiation treatment of renal cell cancer. Cancer Res. 2011;71:1431-41 pubmed 出版商
Gagou M, Zuazua Villar P, Meuth M. Enhanced H2AX phosphorylation, DNA replication fork arrest, and cell death in the absence of Chk1. Mol Biol Cell. 2010;21:739-52 pubmed 出版商
产品信息
SKU号 :
9719S
产品名称 :
磷酸化组蛋白H2A.X(Ser139)(20E3)兔单克隆抗体(Alexa Fluor系列荧光染料®488共轭标签)
规格 :
100微升
Price-(USD) :
291美元
物种x :
H, M
应用 :
流式细胞仪
产品种类 :
Chromatin Regulation / Nuclear Function
运输温度 :
储存温度 :
4°C
产品类型 :
单克隆抗体
宿主 :
靶标 :
H2A组蛋白家族成员X(Ser140)磷酸盐
最初蛋白 :
H2A组蛋白家族成员X
别名 :
H2A histone family, member X,H2A.X,H2AFX,H2AX,H2AX histone,H2a/x,Histone H2A.x
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。