产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
CD8α
目录 :
98941
克隆性 :
单克隆
共轭标签 :
未共轭
克隆名称 :
D4W2Z
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 6k
Zhang Q, Xiu B, Zhang L, Chen M, Chi W, Li L, et al. Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization. J Immunother Cancer. 2022;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 2d
Liu C, Zheng S, Wang Z, Wang S, Wang X, Yang L, et al. KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer. Cancer Commun (Lond). 2022;42:828-847 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6f
Huang S, Si H, Liu J, Qi D, Pei X, Lu D, et al. Sleep Loss Causes Dysfunction in Murine Extraorbital Lacrimal Glands. Invest Ophthalmol Vis Sci. 2022;63:19 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:2000; 图 1f
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, et al. AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells. Cell Rep Med. 2022;3:100554 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s1a
Tang T, Huang X, Zhang G, Lu M, Hong Z, Wang M, et al. Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis. J Immunother Cancer. 2022;10: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6d
Choe D, Lee E, Beeghly Fadiel A, Wilson A, Whalen M, Adunyah S, et al. High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 6
Hoffman K, Villar M, Poveda C, Bottazzi M, Hotez P, Tweardy D, et al. Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Front Cell Infect Microbiol. 2021;11:708325 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 2c, 2f
Wu S, Xiao Y, Wei J, Xu X, Jin X, Hu X, et al. MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer. J Immunother Cancer. 2021;9: pubmed 出版商
  • 免疫组化; 小鼠; 图 s4a
Maier J, Rogg M, Helmstädter M, Sammarco A, Walz G, Werner M, et al. A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s15d
Ho D, Tsui Y, Chan L, Sze K, Zhang X, Cheu J, et al. Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma. Nat Commun. 2021;12:3684 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6
Zhang J, Qi J, Wei H, Lei Y, Yu H, Liu N, et al. TGFβ1 in Cancer-Associated Fibroblasts Is Associated With Progression and Radiosensitivity in Small-Cell Lung Cancer. Front Cell Dev Biol. 2021;9:667645 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 4d
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6a
Morel K, Sheahan A, Burkhart D, Baca S, Boufaied N, Liu Y, et al. EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nat Cancer. 2021;2:444-456 pubmed 出版商
  • 免疫组化; 小鼠; 图 5b
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s6g
Yin H, Zhang X, Yang P, Zhang X, Peng Y, Li D, et al. RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming. Nat Commun. 2021;12:1394 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Adam K, Iuga A, Tocheva A, Mor A. A novel mouse model for checkpoint inhibitor-induced adverse events. PLoS ONE. 2021;16:e0246168 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 5d
Steele N, Biffi G, Kemp S, Zhang Y, Drouillard D, Syu L, et al. Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clin Cancer Res. 2021;: pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 6g
Wang Y, Mohseni M, Grauel A, Diez J, Guan W, Liang S, et al. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms. Sci Rep. 2021;11:1399 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 5e
Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s5
Kasuga A, Semba T, Sato R, Nobusue H, Sugihara E, Takaishi H, et al. Oncogenic KRAS-expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice. Cancer Sci. 2021;112:1822-1838 pubmed 出版商
  • 免疫组化; 小鼠; 图 5f
Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 6d
Li H, Lu C, Zhang H, Hu Q, Zhang J, Cuevas I, et al. A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response. JCI Insight. 2020;5: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 4e
Fan Z, Tian Y, Chen Z, Liu L, Zhou Q, He J, et al. Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors. EMBO Mol Med. 2020;12:e11571 pubmed 出版商
  • 免疫组化; 小鼠; 图 3e
Liu X, Kong W, Peterson C, McGrail D, Hoang A, Zhang X, et al. PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma. Nat Commun. 2020;11:2135 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 8a
Donaldson D, Bradford B, Else K, Mabbott N. Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase. Sci Rep. 2020;10:4554 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 5c
Canon J, Rex K, Saiki A, Mohr C, Cooke K, Bagal D, et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature. 2019;575:217-223 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 e8d
Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al. Targeting cardiac fibrosis with engineered T cells. Nature. 2019;573:430-433 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3g
Sivaram N, McLaughlin P, Han H, Petrenko O, Jiang Y, Ballou L, et al. Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer. J Clin Invest. 2019;130: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 e5c
  • 流式细胞仪; 小鼠; 图 e5b
Yao W, Rose J, Wang W, Seth S, Jiang H, Taguchi A, et al. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019;: pubmed 出版商
  • 免疫组化; 小鼠; 图 4a, 4b
Sorrelle N, Ganguly D, Dominguez A, Zhang Y, Huang H, Dahal L, et al. Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues. J Immunol. 2019;202:292-299 pubmed 出版商
Alvarez M, Molina C, de Andrea C, Fernandez Sendin M, Villalba M, Gonzalez Gomariz J, et al. Intratumoral co-injection of the poly I:C-derivative BO-112 and a STING agonist synergize to achieve local and distant anti-tumor efficacy. J Immunother Cancer. 2021;9: pubmed 出版商
Sun X, Wu B, Chiang H, Deng H, Zhang X, Xiong W, et al. Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. Nature. 2021;599:673-678 pubmed 出版商
Akasu M, Shimada S, Kabashima A, Akiyama Y, Shimokawa M, Akahoshi K, et al. Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma. Sci Rep. 2021;11:16732 pubmed 出版商
Tello Lafoz M, Srpan K, Sanchez E, Hu J, Remšík J, Romin Y, et al. Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer. Immunity. 2021;54:1037-1054.e7 pubmed 出版商
Chan Y, Wang S, Chu C, Copland D, Letizia A, Costa Verdera H, et al. Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Sci Transl Med. 2021;13: pubmed 出版商
Oba T, Long M, Keler T, Marsh H, Minderman H, Abrams S, et al. Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s. Nat Commun. 2020;11:5415 pubmed 出版商
Zhu L, Li Y, Xie X, Zhou X, Gu M, Jie Z, et al. TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis. Nat Cell Biol. 2019;21:1604-1614 pubmed 出版商
Dharmaraj N, Piotrowski S, Huang C, Newton J, Golfman L, Hanoteau A, et al. Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape. Oncoimmunology. 2019;8:e1568809 pubmed 出版商
Gibson H, McKnight B, Malysa A, Dyson G, Wiesend W, McCarthy C, et al. IFNγ PET Imaging as a Predictive Tool for Monitoring Response to Tumor Immunotherapy. Cancer Res. 2018;78:5706-5717 pubmed 出版商
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。