蛋白

重组人类BCL2L11蛋白, 多聚组氨酸标签

BCL2L11-1525H

重组人类BCL2L11蛋白, 多聚组氨酸标签

Creative Biomart

BCL2L11

BCL2-like 11 (apoptosis facilitator)

BCL2L11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl2-L-11; Bcl2 interacting mediator of cell death; bcl2-interacting mediator of cell death; Bim; Bod; 1500006F24Rik

Recombinant human BCL2L11 (aa. 198) produced in E.coli is a 22 kDa protein. It was fused to N-terminal His-tag.

Recombinant human BCL2L11 (aa. 198) produced in E.coli is a 22 kDa protein. It was fused to N-terminal His-tag.Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

Ecoli

95%

Store at -70 C with any protein, exposing Bim recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

O43521