蛋白

重组人类CASP3, 多聚组氨酸标签

CASP3-36H

重组人类CASP3, 多聚组氨酸标签

Creative Biomart

CASP3

caspase 3, apoptosis-related cysteine peptidase

CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; Apopain; CPP-32; EC 3.4.22.56; Yama; procaspase3; Cysteine protease CPP32; PARP cleavage protease; SREBP cleavage activity 1; Yama protein; caspase 3, apoptosis-related cysteine protease

Recombinant Human CASP3 produced in E.coli is a double, non-glycosylated, polypeptide chain cotaning 258 amino acids and having a molecular mass of 29.7 kDa. The Caspase-3 is fused to His-Tag at C-terminus and purified by proprietary chromatographic techniques.

Recombinant Human CASP3 produced in E.coli is a double, non-glycosylated, polypeptide chain cotaning 258 amino acids and having a molecular mass of 29.7 kDa. The Caspase-3 is fused to His-Tag at C-terminus and purified by proprietary chromatographic techniques.CASP3 is part of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspase-3 enzyme results in the execution-phase of cell apoptosis/programmed cell death. Caspase 3 has been called the henchman that goes around and executes the cell. Caspase3 exists as an inactive proenzyme which undergoes proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CSN-mediated deneddylation is regulated by active CASP3. CASP-3 cleavage of RAD51 results in a functional decrease in RAD51 strand exchange activity and inhibition of caspase 3 activity increases RAD51 protein levels.

大肠埃希杆菌

Greater than 90.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

P42574