蛋白

重组人类CASP9

CASP9-618H

重组人类CASP9

Creative Biomart

CASP9

caspase 9, apoptosis-related cysteine peptidase

CASP9; caspase 9, apoptosis-related cysteine peptidase; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; caspase-9; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56;

Recombinant Human CARM1 is produced inE. coli.

Recombinant Human CARM1 is produced inE. coli.Caspase-9 is an initiator caspase encoded by the CASP9 gene. CASP9 orthologs have been identified in all mammals for which complete genome data are available. Unique orthologs are also present in lizards, lissamphibians, and teleosts. The aspartic acid specific protease caspase-9 has been linked to the mitochondrial death pathway. It is activated during programmed cell death (apoptosis). Induction of stress signalling pathways JNK/SAPK causes release of cytochrome c from mitochondria and activation of apaf-1 (apoptosome), which in turn cleaves the pro-enzyme of caspase-9 into the active form. Once initiated caspase-9 goes on to cleave procaspase-3 procaspase-7 and which cleave several cellular targets, including poly ADP ribose polymerase.

大肠杆菌

-80 C

P55211