蛋白

重组人类结缔组织生长因子, 多聚组氨酸标签

CTGF-30H

重组人类结缔组织生长因子, 多聚组氨酸标签

Creative Biomart

CTGF

结缔组织生长因子

CTGF; connective tissue growth factor; CCN2; NOV2; HCS24; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8;

The Connective Tissue Growth Factor His-Tagged Fusion Protein, produced inE. coli, is 38.3 kDa protein containing 323 amino acid residues of the CTGF human and 23 additional amino acid residues – His Tag, Xa - cleavage site (underlined).

The Connective Tissue Growth Factor His-Tagged Fusion Protein, produced inE. coli, is 38.3 kDa protein containing 323 amino acid residues of the CTGF human and 23 additional amino acid residues – His Tag, Xa - cleavage site (underlined).Connective Tissue Growth Factor belongs to the CCN family of proteins. The CCN family presently consists of six members in human also known as: Cyr61 (Cystein rich 61), CTGF (Connective Tissue Growth Factor), Nov (Nephroblastoma Overexpressed gene), WISP-1, 2 and 3 (Wnt-1 Induced Secreted Proteins). The CCN genes encode secreted proteins associated with the Extracellular Matrix (ECM) and cell membrane. CCN proteins are matricellular proteins which are involved in the regulation of various cellular functions including: proliferation, differentiation, survival, adhesion and migration. They are expressed in derivatives of the three embryonic sheets and are implicated in the development of kidney, nervous system, muscle, bone marrow, cartilage and bone. During adulthood, they are implicated in wound healing, bone fracture repair, and pathologies such as: fibrosis, vascular ailments and tumorigenesis. Full length secreted CCN proteins can show an antiproliferative activity, whereas truncated isoforms are likely to stimulate proliferation and behave as oncogenes.

大肠埃希杆菌

Purity of Connective Tissue Growth Factor is 95% (SDS-PAGE analyzed).

P29279