蛋白

重组大鼠Cxcl12蛋白

Cxcl12-65R

重组大鼠Cxcl12蛋白

Creative Biomart

Cxcl12

chemokine (C-X-C motif) ligand 12

CXCL12; chemokine (C-X-C motif) ligand 12; SDF1, SDF1A, SDF1B, stromal cell derived factor 1; stromal cell-derived factor 1; PBSF; SCYB12; SDF 1a; SDF 1b; TLSF a; TLSF b; TPAR1; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor; IRH; SDF1; TLSF; SDF1A; SDF1B

Recombinant Rat SDF-1 alpha produced in E. coli is a single, non-glycosylated polypeptide chain containing 68 amino acids and its molecular weight is 7.9 kDa.

Recombinant Rat SDF-1 alpha produced in E. coli is a single, non-glycosylated polypeptide chain containing 68 amino acids and its molecular weight is 7.9 kDa.SDF-1 and SDF-1 , members of the chemokine subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line. SDF-1 and SDF-1 cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1 and SDF-1 are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 and absent from SDF-1 . SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T-lymphocytes, monocytes, pro- and pre- B cells, but not neutrophils.

大肠埃希杆菌

97% by SDS-PAGE and HPLC analyses.

This lyophilized preparation is stable at 2-8 C, but should be kept at -20 C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 C to -70 C. Avoid repeated freeze/thaw cycles.