蛋白

重组人类DIRAS1, 多聚组氨酸标签

DIRAS1-2817H

重组人类DIRAS1, 多聚组氨酸标签

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DIRAS1

DIRAS family, GTP-binding RAS-like 1

DIRAS1; DIRAS family, GTP-binding RAS-like 1; GTP-binding protein Di-Ras1; Di Ras1; GBTS1; RIG; DIRAS family GTP binding RAS like 1; Distinct subgroup of the Ras family member 1; FLJ42681; GTP binding protein Di Ras1; Ras related inhibitor of cell growth; Rig protein; Small GTP binding tumor suppressor 1; ras-related inhibitor of cell growth; small GTP-binding tumor suppressor 1; Di-Ras1

Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 24.1 kDa (215aa), confirmed by MALDI-TOF.

Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 24.1 kDa (215aa), confirmed by MALDI-TOF.DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form.

Ecoli

液体。 在20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含20% 甘油1mM DTT, 0.1M氯化钠, 1mM乙二胺四乙酸

95% by SDS – PAGE.

1毫克/毫升(由布拉德福德Bradford检测确定)

MGSSHHHHHH SSGLVPRGSH MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG NKCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR VKGKC

可以储存在+4 C短期(1-2周)。 为长期储存, 分成小份儿保存在-20 C或-70 C。 避免反复冻融

O95057