产品简要
公司名称 :
Creative Biomart
产品类型 :
蛋白
产品名称 :
重组小鼠F7, 多聚组氨酸标签
目录 :
F7-8662M
更多信息或购买 :
产品信息
猫 :
F7-8662M
产品名称 :
重组小鼠F7, 多聚组氨酸标签
品牌 :
Creative Biomart
gene symbal :
F7
基因名称 :
coagulation factor VII (serum prothrombin conversion accelerator)
同义词 :
F7; coagulation factor VII; SPCA; eptacog alfa; proconvertin; OTTHUMP00000018733; OTTHUMP00000018734; FVII coagulation protein; serum prothrombin conversion accelerator; factor VII
产品简列 :
A DNA sequence encoding the mouse FⅦ (NP_034302.2) (Met 1-Leu 446) was fused with the a polyhistidine tag at the C-terminus.
描述 :
A DNA sequence encoding the mouse FⅦ (NP_034302.2) (Met 1-Leu 446) was fused with the a polyhistidine tag at the C-terminus.Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels, normally not exposed to the blood stream. The action of the Factor VII is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent and is produced in the liver. The use of warfarin or similar anticoagulants impairs its function. Upon vessel injury, tissue factor is exposed to the blood and circulating Factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself. The most important substrates for FVIIa-TF are Factor X and Factor IX.
来源 :
人类细胞
形式 :
Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
纯度 :
>90 % as determined by SDS-PAGE
储存 :
Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
更多信息或购买 :
公司信息
Creative Biomart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域，提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。