蛋白

重组人类缺氧诱导因子1A, 576-785氨基酸, 多聚组氨酸标签

缺氧诱导因子1A-2773H

重组人类缺氧诱导因子1A, 576-785氨基酸, 多聚组氨酸标签

Creative Biomart

缺氧诱导因子1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

HIF1A; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1-alpha; bHLHe78; HIF 1alpha; HIF1; MOP1; PASD8; HIF-1-alpha; member of PAS protein 1; ARNT interacting protein; ARNT-interacting protein; member of PAS superfamily 1; PAS domain-containing protein 8; basic-helix-loop-helix-PAS protein MOP1; class E basic helix-loop-helix protein 78; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); HIF-1alpha; HIF1-ALPHA

Recombinant human HIF1A(576-785) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 25.1 kDa (231aa).

Recombinant human HIF1A(576-785) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 25.1 kDa (231aa).HIF1A, identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. This protein is a heterodimer composed of HIF-1beta subunit and one of three subunits(HIF-1A, HIF-2A or HIF-3A). The activation of HIF1A is closely associated with a variety of tumors and oncogenic pathways. HIF1A consists of DNA binding domain(DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains(TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains.

Ecoli

液体。 在20 mM三羟甲基氨基甲烷氯化氢缓冲液(pH8.0)含0.2M氯化钠, 1mM DTT, 10% 甘油

85% by SDS - PAGE.

1毫克/毫升(由布拉德福德Bradford检测确定)

MGSSHHHHHH SSGLVPRGSH MSFDQLSPLE SSSASPESAS PQSTVTVFQQ TQI QEPTANA TTTTATTDEL KTVTKDRMED IKILIASPSP THIHKETTSA TSSPYRDTQS RT A SPNRAGK GVIEQTEKSH PRSPNVLSVA LSQRTTVPEE ELNPKILALQ NA QRK RKMEH DGSLFQAVGI GTLLQQPDDH AATTSLSWKR VKGCKSSEQN GME QKTIILI PSDLACRLLG Q

可以储存在+4 C短期(1-2周)。 为长期储存, 分成小份儿保存在-20 C或-70 C。 避免反复冻融

Q16665