蛋白

重组人类NFKB1, 多聚组氨酸标签

NFKB1-633H

重组人类NFKB1, 多聚组氨酸标签

Creative Biomart

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

NFKB1; p50; KBF1; p105; EBP-1; MGC54151; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; DKFZp686C01211; nuclearfactor NF-kappa-Bp105subunit; NF-kappabeta; OTTHUMP00000161765; OTTHUMP00000216418; OTTHUMP00000219572; DNA binding factor KBF1; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B DNA binding subunit

Recombinant Human NFKB1 isproduced inSf21 cellsand fused to a His-tag.

Recombinant Human NFKB1 isproduced inSf21 cellsand fused to a His-tag.This gene encodes a 105 kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kDa protein. The 105 kDa protein is a Rel protein-specific transcription inhibitor and the 50 kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Sf21细胞

0.2毫克/毫升

-80 C. After opening, prepare aliquots and store in liquid nitrogen. Avoid freeze/thaw cycles.

P19838