蛋白

Recombinant Human Nerve Growth Factor (Beta Polypeptide)

神经生长因子-476H

Recombinant Human Nerve Growth Factor (Beta Polypeptide)

Creative Biomart

神经生长因子

nerve growth factor (beta polypeptide)

NGF; nerve growth factor (beta polypeptide); NGFB; HSAN5; Beta-NGF; beta-nerve growth factor; nerve growth factor, beta subunit;

Recombinant Human NGF (Ser 122-Arg 239) was expressed in CHO Cells.

Recombinant Human NGF (Ser 122-Arg 239) was expressed in CHO Cells.As the first one of a series of neurotrophic factors, nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF was identified as a large complex consisting of three non-covalently linked subunits, , , and , among which, the subunit, called -NGF, was demonstrated to exhibits the growth stimulating activity of NGF. -NGF is a target-derived secreted homodimeric protein of two 120-amino acid mature polypeptides after proteolytic removal of the signal and pro peptide. NGF acts via at least two receptors on the surface of cells, TrkA and p75 receptors to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation.

98 % as determined by SDS-PAGE

Store it under sterile conditions at -70 C . It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

P01138