产品简要
公司名称 :
Creative Biomart
产品类型 :
抗体
产品名称 :
人类抗表皮生长因子受体重组抗体(克隆MR1)
目录 :
PABC-040
克隆性 :
重组
宿主 :
人类
共轭标签 :
未共轭
反应物种 :
人类
应用 :
中和反应
更多信息或购买 :
产品信息
猫 :
PABC-040
产品名称 :
人类抗表皮生长因子受体重组抗体(克隆MR1)
品牌 :
Creative Biolabs
Abbr :
抗表皮生长因子受体抗体(克隆MR1)
宿主动物 :
人类
应用 :
中和
靶标 :
表皮生长因子受体
物种活性 :
人类
Antbody Type :
工程抗体
免疫原 :
人类表皮生长因子受体
别称 :
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
UniProt数据库编号 :
P00533
产品简列 :
Recombinant Human Antibody (MR1) is capable of binding to EGFRvIII dodecapeptide (EEKKGNYVVTDH), expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-EGFRvIII dodecapeptide (EEKKGNYVVTDH) mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-EGFRvIII dodecapeptide (EEKKGNYVVTDH) mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. Necitumumab is a recombinant human IgG1 monoclonal antibody that binds to the human epidermal growth factor receptor (EGFR) and blocks the binding of EGFR to its ligands. IMC-11F8 is a fully human antibody that has similar antitumor potency as the chimeric cetuximab/Erbitux and might represent a safer therapeutic alternative.
储存 :
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
更多信息或购买 :
公司信息
Creative Biomart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
公司总部: 美国
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域,提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。