蛋白

重组人类PIK3CG, 谷胱甘肽S-转移酶标签

PIK3CG-55H

重组人类PIK3CG, 谷胱甘肽S-转移酶标签

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PIK3CG

phosphoinositide-3-kinase, catalytic, gamma polypeptide

PIK3CG; phosphoinositide-3-kinase, catalytic, gamma polypeptide; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; p110gamma; p120-PI3K; PI3K-gamma; p110-gamma; PI3-kinase subunit gamma; ptdIns-3-kinase subunit gamma; 1-phosp

The Recombinant Human phosphoinositide-3-kinase, catalytic, gamma polypeptide produced inSf9 insect cellsis a catalytically inactive mutant of PI3Kγ with a D946A mutation in the ATP binding site. This recombinant catalytically inactive protein can be used as a negative control in any kind of PI3Kγ kinase activity studies. Recombinant full length PI3KγDA mutant (126.3 kDa without Tag) carries a N-terminal GST-Tag which facilitates the protein's application in typical GST pull-down assays.

The Recombinant Human phosphoinositide-3-kinase, catalytic, gamma polypeptide produced inSf9 insect cellsis a catalytically inactive mutant of PI3Kγ with a D946A mutation in the ATP binding site. This recombinant catalytically inactive protein can be used as a negative control in any kind of PI3Kγ kinase activity studies. Recombinant full length PI3KγDA mutant (126.3 kDa without Tag) carries a N-terminal GST-Tag which facilitates the protein's application in typical GST pull-down assays.This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Sf9昆虫细胞

Greater than 95.0% as determined by SDS Page.

PI3Kb although stable at 14 C for 1 week, should be stored desiccated below -18 C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

P48736