蛋白

Recombinant Human RELA, C-Terminal Truncated

RELA-627TH

Recombinant Human RELA, C-Terminal Truncated

Creative Biomart

RELA

v-rel reticuloendotheliosis viral oncogene homolog A

RELA; v-rel reticuloendotheliosis viral oncogene homolog A (avian); NFKB3; p65; Nuclear factor NF-kappa-B p65 subunit; MGC131774; transcription factor p65; OTTHUMP00000233473; OTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; v-rel avian reticuloendotheliosis; viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65))

The recombinant human NF-kB p65 protein contains amino acids 1-537, corresponding to GenBank no AA36408.1. This represents a C-terminal truncation of 14 amino acids; the full-length human p65 NF-kB protein is 551 amino acids.

The recombinant human NF-kB p65 protein contains amino acids 1-537, corresponding to GenBank no AA36408.1. This represents a C-terminal truncation of 14 amino acids; the full-length human p65 NF-kB protein is 551 amino acids. NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

The protein was purified by affinity chromatography. The purity is greater than 98.0%.