蛋白

重组人类RELA, 多聚组氨酸标签

RELA-634H

重组人类RELA, 多聚组氨酸标签

Creative Biomart

RELA

v-rel reticuloendotheliosis viral oncogene homolog A

RELA; v-rel reticuloendotheliosis viral oncogene homolog A (avian); NFKB3; p65; Nuclear factor NF-kappa-B p65 subunit; MGC131774; transcription factor p65; OTTHUMP00000233473; OTHUMP00000233474; OTTHUMP00000233475; OTTHUMP00000233476; OTTHUMP00000233900; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; v-rel avian reticuloendotheliosis; viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65))

Recombinant Human RELA isproduced inSf21 cellsand Fused to a His-tag.

Recombinant Human RELA isproduced inSf21 cellsand Fused to a His-tag.NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).

Sf21细胞

≥95%(十二烷基磺酸钠-PAGE)

0.5毫克/毫升

Q04206