蛋白

重组人类选择素L, Fc嵌合体

SELL-451H

重组人类选择素L, Fc嵌合体

Creative Biomart

SELL

选择素, 淋巴细胞

CD62 antigen like family member L; CD62L; CD62L antigen; gp90 MEL; hLHRc; LAM 1; LAM1; LECAM1; Leu 8; LEU8; Leukocyte adhesion molecule 1; Leukocyte endothelial cell adhesion molecule 1; Leukocyte surface antigen Leu 8; LNHR; LSEL; Lyam 1; LYAM1; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L; SELL; TQ1; L-selectin

Recombinant Human selectin L encoding the signal peptide, pro-peptide and extracellular domain of human L-Selectin (aa 1-343) was expressed in modifiedhuman 293 cells. It was fused to the Fc region of human IgG1 (aa 93-330).

Recombinant Human selectin L encoding the signal peptide, pro-peptide and extracellular domain of human L-Selectin (aa 1-343) was expressed in modifiedhuman 293 cells. It was fused to the Fc region of human IgG1 (aa 93-330).L-Selectin (CD62L) is a type I membrane protein expressed on the surface of T cells, B cells, monocytes, neutrophils, macrophages, eosinophils and NK cells. L-Selectin mediates entry of lymphocytes into secondary lymphoid tissue by adherence to endothelial cells of high endothelial venules (HEV). L-Selectin has been considered as a suitable target for treatment or prevention of inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease, allergies and atherosclerosis.

人类293细胞

95%, as determined by SDS-PAGE and visualized by silver stain.

Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C. Repeated freeze thawing is not recommended.

P14151