产品简要
公司名称 :
Creative Biomart
产品类型 :
蛋白
产品名称 :
重组人类TAK1-TAB1, 谷胱甘肽S-转移酶标签, 活性的
目录 :
TAK1-TAB1-440H
更多信息或购买 :
产品信息
猫 :
TAK1-TAB1-440H
产品名称 :
重组人类TAK1-TAB1, 谷胱甘肽S-转移酶标签, 活性的
品牌 :
Creative Biomart
gene symbal :
MAP3K7
基因名称 :
TGF乙激活的激酶1/MAP3K7结合蛋白1
同义词 :
地图;MAP3K;MAP3K7;丝裂原活化蛋白激酶7;TAK1;MEKK7;TGF1a;TGF乙激活的激酶1;转化生长因子β激酶1
产品简列 :
Recombinant human proteins TAK1 (1-303) and TAB1 (437-end), linked by a small peptide (DFGGGGG), were expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 74 kDa.
描述 :
Recombinant human proteins TAK1 (1-303) and TAB1 (437-end), linked by a small peptide (DFGGGGG), were expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 74 kDa.TAK1 is a serine/threonine protein kinase that mediates signaling by TGFβ and morphogenetic protein (BMP). In response to IL-1, TAK1 forms a kinase complex with TAB1 and this complex is required for the activation of nuclear factor kappa B (NfκB). TAK1 can also activate MAPK8/JNK and MAP2K4/MKK4 and thus play a role in the cell response to environmental stress. Tak1 is essential for thymocyte development and activation and deletion of TAK1 prevents maturation of single-positive thymocytes displaying CD4 or CD8. Thymocytes lacking TAK1 fail to activate NfκB and JNK and are prone to apoptosis upon stimulation.
来源 :
Sf9昆虫细胞美国杆状病毒
UniProt数据库编号 :
O43318Q15750
更多信息或购买 :
公司信息
Creative Biomart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域，提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。