蛋白

重组人类转化生长因子1

转化生长因子1-346H

重组人类转化生长因子1

Creative Biomart

转化生长因子1

转化生长因子1转化生长因子, 乙1[人(人类)]

TGFB1; CED; LAP; DPD1; TGFB; TGFbeta; transforming growth factor, beta 1; transforming growth factor beta-1; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide

Recombinant human TGF-b1 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

CHO细胞

Greater than 98% by SDS-PAGE gel and HPLC analyses.

P01137