产品简要
公司名称 :
Creative Biomart
产品类型 :
蛋白
产品名称 :
Recombinant Danio rerio (zebrafish) bmp2a
目录 :
bmp2a-8706D
更多信息或购买 :
产品信息
猫 :
bmp2a-8706D
产品名称 :
Recombinant Danio rerio (zebrafish) bmp2a
品牌 :
Creative Biomart
gene symbal :
bmp2a
产品简列 :
A DNA sequence encoding the zebrafish BMP2A (B3DI86) (Gln272-Arg386) was expressed and purified with an initial Met.
描述 :
A DNA sequence encoding the zebrafish BMP2A (B3DI86) (Gln272-Arg386) was expressed and purified with an initial Met.Bone morphogenetic protein 2 (BMP2) is a member of the BMP subgroup belonging to the transforming growth factor (TGF)-beta superfamily. The mature BMP2 acts as disulfide-linked homodimers and heterodimers with BMP-7 after proteolytic removal of propeptide. BMP2 is capable of inducing the formation of cartilage and bone but are now regarded as multifunctional cytokines. It binds heterodimeric receptor complexes composed of a type I receptor and a type I I receptor, and transduces the related signals via the down-stream molecules, such as the PI3 kinase, Smads, STATs, etc. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function. In addition, recent studies have revealed that osteoblast-derived BMP2 enhances the migration of prostate cancer cells. rhBMP2 can be utilized in various therapeutic interventions such as bony defects, delayed union, non-union fractures and osteoporosis.
来源 :
Ecoli
形式 :
Lyophilized from sterile 30mM HAC, pH 3.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
纯度 :
>95 % as determined by SDS-PAGE
储存 :
Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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公司信息
Creative Biomart
Creative Biomart为生物研究、临床研究、分子诊断及生物药物研发等领域，提供高质量的重组蛋白、诊断用抗原抗体、诊断用酶及制药用酶等产品。