产品简要
公司名称 :
DIMA Biotechnology
产品类型 :
抗体
产品名称 :
抗CD38抗体(DM28), 兔单克隆抗体
目录 :
DME100027
规格 :
10微升, 100微升
价格 :
60美元, 398美元
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
DM28
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
图像
图像 1 :
Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human CD38(right) were surface stained with Rabbit anti-CD38 monoclonal antibody 1μg/ml (clone: DM28) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
图像 2 :
Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human CD38(right) were surface stained with Rabbit anti-CD38 monoclonal antibody 1μg/ml (clone: DM28) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
图像 3 :
Figure 2. Flow cytometry data of serially titrated Rabbit anti-CD38 monoclonal antibody ( clone: DM28 ) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
产品信息
目录代码 :
DME100027
产品名称 :
抗CD38抗体(DM28), 兔单克隆抗体
产品类型 :
抗体
宿主物种 :
兔
克隆性 :
单克隆
共轭 :
未共轭
抗原修饰 :
no modification
克隆名称 :
DM28
抗体亚型 :
兔IgG
照明链 :
kappa
规格 :
10微升, 100微升
标价 :
60美元, 398美元
物种摘要 :
人类
背景 :
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
免疫原 :
Recombinant human CD38 (Val43-IIe300) (PME100004) produced by using human HEK293 cells
特异性 :
ELISA,Flow Cyt
纯度 :
Purified from cell culture supernatant by affinity chromatography
缓冲液 :
50% 甘油;PBS, pH值7.4;0.1% BSA
防腐剂 :
0.1% ProClin防腐剂300
包装 :
10微升/100微升
用途 :
研究美国只有
应用摘要 :
Flow Cyt 1/100; MMTumor cell killing
储存 :
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
更多信息或购买 :
公司信息
DIMA Biotechnology
Wuhan institute of Biotechnology B7
Biolake No.666 Gaoxin Road
Wuhan, Hubei
Biolake No.666 Gaoxin Road
Wuhan, Hubei
info@dimabio.com
https://www.dimabio.com0118615307149771
公司总部: 中国
DIMA BIOTECH LTD (DIMABIO) focuses exclusively on the pre-clinical research market of Immune Oncology. Currently, we offer functional proteins and recombinant monoclonal antibodies. Our proprietary DimAb™ technology platform can directly clone IgG gene from immunized animal, which is a technology breakthrough in monoclonal antibody development.
All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.
All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.