产品简要
公司名称 :
丹科医疗器械技术服务(上海)有限公司
产品类型 :
抗体
产品名称 :
Tau
目录 :
A0024
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, immunohistochemistry - free floating section, 免疫印迹基因敲除验证
文章摘录数: 49
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 小鼠; 1:10,000; 图 1f
Freixo F, Martínez Delgado P, Manso Y, Sánchez Huertas C, Lacasa C, Soriano E, et al. NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. Nat Commun. 2018;9:2330 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 10f
  • 免疫印迹; 人类; 图 6g
  • 免疫印迹基因敲除验证; 小鼠; 图 6g
Ercan E, Eid S, Weber C, Kowalski A, Bichmann M, Behrendt A, et al. A validated antibody panel for the characterization of tau post-translational modifications. Mol Neurodegener. 2017;12:87 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000; 图 1a
  • 免疫印迹; 人类; 1:5000; 图 s5b
Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:5000; 图 9b
Laporte M, Chatellard C, Vauchez V, Hemming F, Deloulme J, Vossier F, et al. Alix is required during development for normal growth of the mouse brain. Sci Rep. 2017;7:44767 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 图 1e
  • 免疫印迹; 小鼠; 图 1a
Croft C, Wade M, Kurbatskaya K, Mastrandreas P, Hughes M, Phillips E, et al. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death Dis. 2017;8:e2671 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6a
Trzeciakiewicz H, Tseng J, Wander C, Madden V, Tripathy A, Yuan C, et al. A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy. Sci Rep. 2017;7:44102 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2j
Stachowicz A, Olszanecki R, Suski M, Głombik K, Basta Kaim A, Adamek D, et al. Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2). Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 7a
Karikari T, Turner A, Stass R, Lee L, Wilson B, Nagel D, et al. Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag. Protein Expr Purif. 2017;130:44-54 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4a
Sun W, Lee S, Huang X, Liu S, Inayathullah M, Kim K, et al. Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment. Sci Rep. 2016;6:34784 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 表 s4
Hansen S, Stummann T, Borland H, Hasholt L, Tumer Z, Nielsen J, et al. Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3. Stem Cell Res. 2016;17:306-317 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 4
Tiwari S, Mizuno K, Ghosh A, Aziz W, Troakes C, Daoud J, et al. Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss. Brain. 2016;139:2751-2765 pubmed
  • 免疫印迹; 小鼠; 图 2f
  • 免疫印迹; 人类; 图 2f
Hernandez Rapp J, Rainone S, Goupil C, Dorval V, Smith P, Saint Pierre M, et al. microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice. Sci Rep. 2016;6:30953 pubmed 出版商
  • 免疫印迹; 人类; 图 s7c
Lee S, Le Pichon C, Adolfsson O, Gafner V, Pihlgren M, Lin H, et al. Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement. Cell Rep. 2016;16:1690-1700 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 5
Li T, Braunstein K, Zhang J, Lau A, Sibener L, Deeble C, et al. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nat Commun. 2016;7:12082 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:3200; 图 5
Adams S, Tilton K, Kozubek J, Seshadri S, Delalle I. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. J Neuropathol Exp Neurol. 2016;75:779-790 pubmed
  • immunohistochemistry - free floating section; 人类; 1:5000
  • 免疫印迹; 人类; 1:10,000; 图 4
  • 免疫印迹; 小鼠; 1:10,000; 图 4
Wu J, Hussaini S, Bastille I, Rodriguez G, Mrejeru A, Rilett K, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nat Neurosci. 2016;19:1085-92 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Yetman M, Fowler S, Jankowsky J. Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction. PLoS ONE. 2016;11:e0153724 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Yousuf M, Tan C, Torres Altoro M, Lu F, Plautz E, Zhang S, et al. Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury. J Neurochem. 2016;138:317-27 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Winston C, Noël A, Neustadtl A, Parsadanian M, Barton D, Chellappa D, et al. Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma. Am J Pathol. 2016;186:552-67 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 3
Bougé A, Parmentier M. Tau excess impairs mitosis and kinesin-5 function, leading to aneuploidy and cell death. Dis Model Mech. 2016;9:307-19 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Chesser A, Ganeshan V, Yang J, Johnson G. Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons. Nutr Neurosci. 2016;19:21-31 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1a
  • 免疫细胞化学; 小鼠; 1:1000; 图 1a
Takeda S, Wegmann S, Cho H, DeVos S, Commins C, Roe A, et al. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain. Nat Commun. 2015;6:8490 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Parsi S, Smith P, Goupil C, Dorval V, Hébert S. Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease. Mol Ther Nucleic Acids. 2015;4:e256 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Smith P, Hernandez Rapp J, Jolivette F, Lecours C, Bisht K, Goupil C, et al. miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo. Hum Mol Genet. 2015;24:6721-35 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20000
Wang D, Kinoshita Y, Kinoshita C, Uo T, Sopher B, Cudaback E, et al. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain. 2015;138:2005-19 pubmed 出版商
  • immunohistochemistry - free floating section; 人类; 1:200
Erro Aguirre M, Zelaya M, Sánchez Ruiz de Gordoa J, Tuñón M, Lanciego J. Midbrain catecholaminergic neurons co-express α-synuclein and tau in progressive supranuclear palsy. Front Neuroanat. 2015;9:25 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Kaufman A, Salazar S, Haas L, Yang J, Kostylev M, Jeng A, et al. Fyn inhibition rescues established memory and synapse loss in Alzheimer mice. Ann Neurol. 2015;77:953-71 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 4
Piatti P, Lim C, Nat R, Villunger A, Geley S, Shue Y, et al. Embryonic stem cell differentiation requires full length Chd1. Sci Rep. 2015;5:8007 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Melis V, Zabke C, Stamer K, Magbagbeolu M, Schwab K, Marschall P, et al. Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration. Cell Mol Life Sci. 2015;72:2199-222 pubmed 出版商
  • 免疫印迹; 人类
Zhou Y, Hayashi I, Wong J, Tugusheva K, Renger J, Zerbinatti C. Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease. PLoS ONE. 2014;9:e103187 pubmed 出版商
  • 免疫印迹; 人类
Zhao Z, Wu L, Xiong R, Wang L, Zhang B, Wang C, et al. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease. Neuroscience. 2014;275:232-7 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:2000; 图 2
Petry F, Pelletier J, Bretteville A, Morin F, Calon F, Hébert S, et al. Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions. PLoS ONE. 2014;9:e94251 pubmed 出版商
  • 免疫组化; 人类
Steffensen K, Smoter M, Waldstrøm M, Grala B, Bodnar L, Stec R, et al. Resistance to first line platinum paclitaxel chemotherapy in serous epithelial ovarian cancer: the prediction value of ERCC1 and Tau expression. Int J Oncol. 2014;44:1736-44 pubmed 出版商
  • 免疫组化; 人类; 1:1,000
Coppieters N, Dieriks B, Lill C, Faull R, Curtis M, Dragunow M. Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain. Neurobiol Aging. 2014;35:1334-44 pubmed 出版商
  • 免疫组化; 人类
Ruzicka J, Romanyuk N, Hejcl A, Vetrik M, Hruby M, Cocks G, et al. Treating spinal cord injury in rats with a combination of human fetal neural stem cells and hydrogels modified with serotonin. Acta Neurobiol Exp (Wars). 2013;73:102-15 pubmed
Stefanoska K, Volkerling A, Bertz J, Poljak A, Ke Y, Ittner L, et al. An N-terminal motif unique to primate tau enables differential protein-protein interactions. J Biol Chem. 2018;293:3710-3719 pubmed 出版商
Rodriguez Rodriguez P, Sandebring Matton A, Merino Serrais P, Parrado Fernandez C, Rabano A, Winblad B, et al. Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons. Brain. 2017;: pubmed 出版商
Kurbatskaya K, Phillips E, Croft C, Dentoni G, Hughes M, Wade M, et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathol Commun. 2016;4:34 pubmed 出版商
Maj M, Hoermann G, Rasul S, Base W, Wagner L, Attems J. The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells. J Diabetes Res. 2016;2016:1964634 pubmed 出版商
Whittington R, Virág L, Gratuze M, Petry F, Noël A, Poitras I, et al. Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro. Neurobiol Aging. 2015;36:2414-28 pubmed 出版商
Smoter M, Bodnar L, Grala B, Stec R, Zieniuk K, Kozlowski W, et al. Tau protein as a potential predictive marker in epithelial ovarian cancer patients treated with paclitaxel/platinum first-line chemotherapy. J Exp Clin Cancer Res. 2013;32:25 pubmed 出版商
Maj M, Milenkovic I, Bauer J, Berggard T, Veit M, Ilhan Mutlu A, et al. Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture. Front Mol Neurosci. 2012;5:84 pubmed 出版商
Julien C, Marcouiller F, Bretteville A, El Khoury N, Baillargeon J, Hébert S, et al. Dimethyl sulfoxide induces both direct and indirect tau hyperphosphorylation. PLoS ONE. 2012;7:e40020 pubmed 出版商
Bretteville A, Marcouiller F, Julien C, El Khoury N, Petry F, Poitras I, et al. Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors. Sci Rep. 2012;2:480 pubmed 出版商
Whittington R, Virag L, Marcouiller F, Papon M, El Khoury N, Julien C, et al. Propofol directly increases tau phosphorylation. PLoS ONE. 2011;6:e16648 pubmed 出版商
Stieler J, Bullmann T, Kohl F, Tøien Ø, Brückner M, Hartig W, et al. The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS ONE. 2011;6:e14530 pubmed 出版商
公司信息
丹科医疗器械技术服务(上海)有限公司
上海市虹口区四川北路1350号中信泰富申虹广场17楼
china@dako.com
www.dako.com/cn/index.htm
86-21-3612 7091
公司总部: 美国
作为Agilent Technologies Company的子品牌,Dako为癌症研究提供高质量的试剂、仪器及软件等产品和服务。