产品简要
公司名称 :
丹科医疗器械技术服务(上海)有限公司
产品类型 :
抗体
产品名称 :
c-erbB-2 Oncoprotein
目录 :
A0485
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 68
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1.6 ug/ml; 图 3d
Kwon S, Cho C, Kwon Y, Lee E, Park J. A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis. Sci Rep. 2017;7:45968 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Andreev J, Thambi N, Perez Bay A, Delfino F, Martin J, Kelly M, et al. Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs. Mol Cancer Ther. 2017;16:681-693 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 1a
Day K, Lorenzatti Hiles G, Kozminsky M, Dawsey S, Paul A, Broses L, et al. HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone. Cancer Res. 2017;77:74-85 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 1
Showler K, Nishimura M, Daino K, Imaoka T, Nishimura Y, Morioka T, et al. Analysis of genes involved in the PI3K/Akt pathway in radiation- and MNU-induced rat mammary carcinomas. J Radiat Res. 2017;58:183-194 pubmed 出版商
  • 免疫沉淀; 人类; 图 1b
  • 免疫细胞化学; 人类; 图 1a
  • 免疫印迹; 人类; 图 1b
Khan S, Sikander M, Ebeling M, Ganju A, Kumari S, Yallapu M, et al. MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression. Oncogene. 2017;36:491-500 pubmed 出版商
  • 免疫印迹; 狗; 1:1000; 图 1a
Gray M, Lee S, McDowell A, Erskine M, Loh Q, Grice O, et al. Dual targeting of EGFR and ERBB2 pathways produces a synergistic effect on cancer cell proliferation and migration in vitro. Vet Comp Oncol. 2017;15:890-909 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6c
Lloyd Lewis B, Davis F, Harris O, Hitchcock J, Lourenco F, Pasche M, et al. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods. Breast Cancer Res. 2016;18:127 pubmed
  • 免疫印迹; 人类; 1:200; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:250; 表 1
Min L, Zhang C, Ma R, Li X, Yuan H, Li Y, et al. Overexpression of synuclein-? predicts lack of benefit from radiotherapy for breast cancer patients. BMC Cancer. 2016;16:717 pubmed 出版商
  • 免疫组化; 人类; 图 1
de Geus S, Boogerd L, Swijnenburg R, Mieog J, Tummers W, Prevoo H, et al. Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery. Mol Imaging Biol. 2016;18:807-819 pubmed
  • 免疫组化-石蜡切片; 人类; 1:400; 图 s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed 出版商
  • 免疫印迹; 猫; 1:3500; 图 5b
Soares M, Ribeiro R, Najmudin S, Gameiro A, Rodrigues R, Cardoso F, et al. Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status. Oncotarget. 2016;7:17314-26 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1.28 ug/ml; 表 s2
Dupouy D, Ciftlik A, Fiche M, Heintze D, Bisig B, de Leval L, et al. Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer. Sci Rep. 2016;6:20277 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:1500; 图 2
Jung Y, Kim H, Koo J. Expression of Lipid Metabolism-Related Proteins in Metastatic Breast Cancer. PLoS ONE. 2015;10:e0137204 pubmed 出版商
  • 免疫组化; 人类; 1:2000
Mundim F, Pasini F, Brentani M, Soares F, Nonogaki S, Waitzberg A. MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases. Mol Clin Oncol. 2015;3:506-514 pubmed
  • 免疫组化-石蜡切片; 人类; 1:25; 图 2
Dodbiba L, Teichman J, Fleet A, Thai H, Starmans M, Navab R, et al. Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers. PLoS ONE. 2015;10:e0121872 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Falkenberg N, Anastasov N, Schaub A, Radulovic V, Schmitt M, Magdolen V, et al. Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget. 2015;6:8103-14 pubmed
  • 免疫组化-石蜡切片; 人类; 1:1500; 表 3
Kim S, Lee Y, Koo J. Differential expression of lipid metabolism-related proteins in different breast cancer subtypes. PLoS ONE. 2015;10:e0119473 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3f
Meneses Lorente G, Friess T, Kolm I, Hölzlwimmer G, Bader S, Meille C, et al. Preclinical pharmacokinetics, pharmacodynamics, and efficacy of RG7116: a novel humanized, glycoengineered anti-HER3 antibody. Cancer Chemother Pharmacol. 2015;75:837-50 pubmed 出版商
  • 免疫印迹; 人类
Rayavarapu R, Heiden B, Pagani N, Shaw M, Shuff S, Zhang S, et al. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. J Biol Chem. 2015;290:8722-33 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 3
Heskamp S, Boerman O, Molkenboer Kuenen J, Wauters C, Strobbe L, Mandigers C, et al. Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients. PLoS ONE. 2015;10:e0117745 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hole S, Pedersen A, Hansen S, Lundqvist J, Yde C, Lykkesfeldt A. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane. Int J Oncol. 2015;46:1481-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Falkenberg N, Anastasov N, Höfig I, Bashkueva K, Lindner K, Höfler H, et al. Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo. Mol Oncol. 2015;9:282-94 pubmed 出版商
  • 免疫组化; 人类; 1:200
Wang Q, Zhou J, Guo J, Teng R, Shen J, Huang Y, et al. Lin28 promotes Her2 expression and Lin28/Her2 predicts poorer survival in gastric cancer. Tumour Biol. 2014;35:11513-21 pubmed 出版商
  • 免疫组化; 人类; 1:200
Cha Y, Han S, Seol H, Oh D, Im S, Bang Y, et al. Immunohistochemical features associated with sensitivity to lapatinib-plus-capecitabine and resistance to trastuzumab in HER2-positive breast cancer. Anticancer Res. 2014;34:4275-80 pubmed
  • 免疫组化; 人类
Mountzios G, Aivazi D, Kostopoulos I, Kourea H, Kouvatseas G, Timotheadou E, et al. Differential expression of the insulin-like growth factor receptor among early breast cancer subtypes. PLoS ONE. 2014;9:e91407 pubmed 出版商
Iyer P, Shrikhande S, Ranjan M, Joshi A, Gardi N, Prasad R, et al. ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer. Int J Cancer. 2019;144:2008-2019 pubmed 出版商
Yokota T, Serizawa M, Hosokawa A, Kusafuka K, Mori K, Sugiyama T, et al. PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue. BMC Cancer. 2018;18:826 pubmed 出版商
Hashmi A, Aijaz S, Mahboob R, Khan S, Irfan M, Iftikhar N, et al. Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast. BMC Res Notes. 2018;11:531 pubmed 出版商
Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, et al. Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. Breast Cancer Res. 2018;20:59 pubmed 出版商
Mudduwa L, Peiris H, Gunasekara S, Abeysiriwardhana D, Liyanage N, Rayala S, et al. KIBRA; a novel biomarker predicting recurrence free survival of breast cancer patients receiving adjuvant therapy. BMC Cancer. 2018;18:589 pubmed 出版商
Mercogliano M, Inurrigarro G, De Martino M, Venturutti L, Rivas M, Cordo Russo R, et al. Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer. BMC Cancer. 2017;17:895 pubmed 出版商
Halle M, Tangen I, Berg H, Hoivik E, Mauland K, Kusonmano K, et al. HER2 expression patterns in paired primary and metastatic endometrial cancer lesions. Br J Cancer. 2017;: pubmed 出版商
Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed 出版商
Murawski M, Wozniak M, Duś Szachniewicz K, Kołodziej P, Rzeszutko M, Ziółkowski P. Significance of Matrix Metalloproteinase 9 Expression as Supporting Marker to Cytokeratin 19 mRNA in Sentinel Lymph Nodes in Breast Cancer Patients. Int J Mol Sci. 2016;17: pubmed 出版商
Makatsoris T, Tsamandas A, Strimpakos A, Alexopoulou Z, Dionysopoulos D, Pervana S, et al. HER Family Protein Expression in a Greek Population with Gastric Cancer. A Retrospective Hellenic Cooperative Oncology Group Study. Anticancer Res. 2016;36:1581-90 pubmed
Engels C, Kiderlen M, Bastiaannet E, van Eijk R, Mooyaart A, Smit V, et al. The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population: a FOCUS study analysis. Breast Cancer Res Treat. 2016;156:361-70 pubmed 出版商
Liu W, Wang L, Chen J, Yuan J, Xiang Q, Yang G, et al. Application of multispectral imaging in quantitative immunohistochemistry study of breast cancer: a comparative study. Tumour Biol. 2016;37:5013-24 pubmed 出版商
Zhao L, Liu H, Wei Q, Xu G, Wu J, Xu H, et al. Contrast-Enhanced Ultrasonography Features of Breast Malignancies with Different Sizes: Correlation with Prognostic Factors. Biomed Res Int. 2015;2015:613831 pubmed 出版商
Fabi A, Giannarelli D, Malaguti P, Ferretti G, Vari S, Papaldo P, et al. Prospective study on nanoparticle albumin-bound paclitaxel in advanced breast cancer: clinical results and biological observations in taxane-pretreated patients. Drug Des Devel Ther. 2015;9:6177-83 pubmed 出版商
Chen S, Huang L, Chen C, Shao Z. Progesterone receptor loss identifies luminal-type local advanced breast cancer with poor survival in patients who fail to achieve a pathological complete response to neoadjuvant chemotherapy. Oncotarget. 2015;6:18174-82 pubmed
Dupouy S, Doan V, Wu Z, Mourra N, Liu J, De Wever O, et al. Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice. Oncotarget. 2014;5:8235-51 pubmed
Shen S, Sun Q, Liang Z, Cui X, Ren X, Chen H, et al. A prognostic model of triple-negative breast cancer based on miR-27b-3p and node status. PLoS ONE. 2014;9:e100664 pubmed 出版商
Jiang H, Bai X, Meng F, Zhang C, Zhang X. Evaluation of chromosome 17 polysomy in breast cancer by FISH analysis of whole nuclei, and its clinicopathological significance. Oncol Lett. 2014;7:1954-1958 pubmed
Wege A, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, et al. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. MAbs. 2014;6:968-77 pubmed 出版商
Falkenberg N, Anastasov N, Rappl K, Braselmann H, Auer G, Walch A, et al. MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion. Br J Cancer. 2013;109:2714-23 pubmed 出版商
Yang P, Du C, Kwan M, Liang S, Zhang G. The impact of p53 in predicting clinical outcome of breast cancer patients with visceral metastasis. Sci Rep. 2013;3:2246 pubmed 出版商
Takagi K, Ishida T, Miki Y, Hirakawa H, Kakugawa Y, Amano G, et al. Intratumoral concentration of estrogens and clinicopathological changes in ductal carcinoma in situ following aromatase inhibitor letrozole treatment. Br J Cancer. 2013;109:100-8 pubmed 出版商
Assadi M, Lamerz J, Jarutat T, Farfsing A, Paul H, Gierke B, et al. Multiple protein analysis of formalin-fixed and paraffin-embedded tissue samples with reverse phase protein arrays. Mol Cell Proteomics. 2013;12:2615-22 pubmed 出版商
Palmieri C, Gojis O, Rudraraju B, Stamp Vincent C, Wilson D, Langdon S, et al. Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance. Br J Cancer. 2013;108:2039-44 pubmed 出版商
Ludyga N, Englert S, Pflieger K, Rauser S, Braselmann H, Walch A, et al. The impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancer. Mol Cancer. 2013;12:28 pubmed 出版商
Henjes F, Bender C, Von der Heyde S, Braun L, Mannsperger H, Schmidt C, et al. Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs. Oncogenesis. 2012;1:e16 pubmed 出版商
Denkert C, Huober J, Loibl S, Prinzler J, Kronenwett R, Darb Esfahani S, et al. HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer. Breast Cancer Res. 2013;15:R11 pubmed 出版商
Chu P, Hsu N, Liao A, Shih N, Hou M, Liu C. Overexpression of ?-enolase correlates with poor survival in canine mammary carcinoma. BMC Vet Res. 2011;7:62 pubmed 出版商
Berg D, Wolff C, Langer R, Schuster T, Feith M, Slotta Huspenina J, et al. Discovery of new molecular subtypes in oesophageal adenocarcinoma. PLoS ONE. 2011;6:e23985 pubmed 出版商
Tan L, Xu Y, Yu Y, Li X, Chen Y, Feng Y. Serum HER2 level measured by dot blot: a valid and inexpensive assay for monitoring breast cancer progression. PLoS ONE. 2011;6:e18764 pubmed 出版商
Komarova T, Kosorukov V, Frolova O, Petrunia I, Skrypnik K, Gleba Y, et al. Plant-made trastuzumab (herceptin) inhibits HER2/Neu+ cell proliferation and retards tumor growth. PLoS ONE. 2011;6:e17541 pubmed 出版商
Forster J, Paul A, Harnden P, Knowles M. Expression of NRG1 and its receptors in human bladder cancer. Br J Cancer. 2011;104:1135-43 pubmed 出版商
Aubele M, Spears M, Ludyga N, Braselmann H, Feuchtinger A, Taylor K, et al. In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissues. Br J Cancer. 2010;103:663-7 pubmed 出版商
Vogel U. Confirmation of a low HER2 positivity rate of breast carcinomas - limitations of immunohistochemistry and in situ hybridization. Diagn Pathol. 2010;5:50 pubmed 出版商
Mori N, Kyo S, Nakamura M, Hashimoto M, Maida Y, Mizumoto Y, et al. Expression of HER-2 affects patient survival and paclitaxel sensitivity in endometrial cancer. Br J Cancer. 2010;103:889-98 pubmed 出版商
Feng W, Orlandi R, Zhao N, Carcangiu M, Tagliabue E, Xu J, et al. Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers. BMC Cancer. 2010;10:378 pubmed 出版商
Gul A, Keser S, Barisik N, Kandemir N, Cakir C, Sensu S, et al. The relationship of cerb B 2 expression with estrogen receptor and progesterone receptor and prognostic parameters in endometrial carcinomas. Diagn Pathol. 2010;5:13 pubmed 出版商
Hoover A, Strand G, Nowicki P, Anderson M, Vermeer P, Klingelhutz A, et al. Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway. Oncogene. 2009;28:3960-70 pubmed 出版商
Hipp S, Walch A, Schuster T, Losko S, Laux H, Bolton T, et al. Activation of epidermal growth factor receptor results in snail protein but not mRNA overexpression in endometrial cancer. J Cell Mol Med. 2009;13:3858-67 pubmed 出版商
Sato Kuwabara Y, Neves J, Fregnani J, Sallum R, Soares F. Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry. BMC Cancer. 2009;9:6 pubmed 出版商
公司信息
丹科医疗器械技术服务(上海)有限公司
上海市虹口区四川北路1350号中信泰富申虹广场17楼
china@dako.com
http://www.dako.com/cn/index.htm
86-21-3612 7091
公司总部: 美国
作为Agilent Technologies Company的子品牌,Dako为癌症研究提供高质量的试剂、仪器及软件等产品和服务。