产品简要
公司名称 :
丹科医疗器械技术服务(上海)有限公司
产品类型 :
抗体
产品名称 :
BCL2 Oncoprotein
目录 :
M0887
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
124
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray, 其他
文章摘录数: 68
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 图 s1a
  • 免疫印迹; 人类; 图 s1a
Guttà C, Rahman A, Aura C, Dynoodt P, Charles E, Hirschenhahn E, et al. Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma. Cell Death Dis. 2020;11:124 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 2
  • 流式细胞仪; 人类
Debliquis A, Voirin J, Harzallah I, Maurer M, Lerintiu F, Drenou B, et al. Cytomorphology and flow cytometry of brain biopsy rinse fluid enables faster and multidisciplinary diagnosis of large B-cell lymphoma of the central nervous system. Cytometry B Clin Cytom. 2018;94:182-188 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 4
Shimono J, Miyoshi H, Kamimura T, Eto T, Miyagishima T, Sasaki Y, et al. Clinicopathological features of primary splenic follicular lymphoma. Ann Hematol. 2017;96:2063-2070 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2e
Verdanet E, Dereure O, René C, Tempier A, Benammar Hafidi A, Gallo M, et al. Diagnostic value of STMN1, LMO2, HGAL, AID expression and 1p36 chromosomal abnormalities in primary cutaneous B cell lymphomas. Histopathology. 2017;71:648-660 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 st2
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6b
  • 免疫印迹; 人类; 图 6a
Silva B, Barbosa M, Andrade P, Ferreira H, Nery J, Corte Real S, et al. Autophagy Is an Innate Mechanism Associated with Leprosy Polarization. PLoS Pathog. 2017;13:e1006103 pubmed 出版商
  • 免疫印迹; 人类
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2f
  • 免疫组化; 人类; 图 1f
Soon G, Ow G, Chan H, Ng S, Wang S. Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases. Ann Diagn Pathol. 2016;24:40-6 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 表 2
Gallo M, Cacheux V, Vincent L, Bret C, Tempier A, Guittard C, et al. Leukemic non-nodal mantle cell lymphomas have a distinct phenotype and are associated with deletion of PARP1 and 13q14. Virchows Arch. 2016;469:697-706 pubmed
  • 免疫印迹; 人类; 图 5b,5c,6b,6c,6d
Pomares H, Palmeri C, Iglesias Serret D, Moncunill Massaguer C, Saura Esteller J, Núñez Vázquez S, et al. Targeting prohibitins induces apoptosis in acute myeloid leukemia cells. Oncotarget. 2016;7:64987-65000 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 1
Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, et al. SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. Cancer Sci. 2016;107:1270-80 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5c
Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, et al. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival. Sci Rep. 2016;6:26521 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 表 1
Tuşaliu M, Zainea V, Mogoantă C, Dragu A, GoanŢă C, Niţescu M, et al. Diagnostic and therapeutic aspects in malignant sinonasal lymphoma. Rom J Morphol Embryol. 2016;57:233-6 pubmed
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 3
Li Y, Ma H, Lu Y, Tan B, Xu L, Lawal T, et al. Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E2 in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis. Biomed Res Int. 2016;2016:2574637 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2d
van der Heijden M, Zimberlin C, Nicholson A, Colak S, Kemp R, Meijer S, et al. Bcl-2 is a critical mediator of intestinal transformation. Nat Commun. 2016;7:10916 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:160; 图 1c
van den Brand M, Balagué O, van Cleef P, Groenen P, Hebeda K, de Jong D, et al. A subset of low-grade B cell lymphomas with a follicular growth pattern but without a BCL2 translocation shows features suggestive of nodal marginal zone lymphoma. J Hematop. 2016;9:3-8 pubmed
  • 免疫组化-石蜡切片; 人类; 表 4
Adighibe O, Leek R, Fernandez Mercado M, Hu J, Snell C, Gatter K, et al. Why some tumours trigger neovascularisation and others don't: the story thus far. Chin J Cancer. 2016;35:18 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 2
Lamba Saini M, Bouzin C, Weynand B, Marbaix E. An Appraisal of Proliferation and Apoptotic Markers in Papillary Thyroid Carcinoma: An Automated Analysis. PLoS ONE. 2016;11:e0148656 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Soriano A, París Coderch L, Jubierre L, Martínez A, Zhou X, Piskareva O, et al. MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes. Oncotarget. 2016;7:9271-87 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Wojtuszkiewicz A, Schuurhuis G, Kessler F, Piersma S, Knol J, Pham T, et al. Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis. Mol Cell Proteomics. 2016;15:1281-98 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:40; 图 3
Abdel Hamid A, Firgany A, Ali E. Effect of memantine: A NMDA receptor blocker, on ethambutol-induced retinal injury. Ann Anat. 2016;204:86-92 pubmed 出版商
  • 免疫组化; 人类; 1:50; 表 1
Martínez Martínez M, Mosqueda Taylor A, Delgado Azañero W, Rumayor Piña A, de Almeida O. Primary intraosseous squamous cell carcinoma arising in an odontogenic keratocyst previously treated with marsupialization: case report and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121:e87-95 pubmed 出版商
  • 免疫组化; 人类; 1:25; 图 s2
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Moncunill Massaguer C, Saura Esteller J, Pérez Perarnau A, Palmeri C, Núñez Vázquez S, Cosialls A, et al. A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation. Oncotarget. 2015;6:41750-65 pubmed 出版商
  • 免疫组化; 人类; 1:50
Adachi K, Miki Y, Saito R, Hata S, Yamauchi M, Mikami Y, et al. Intracrine steroid production and mammalian target of rapamycin pathways in pulmonary lymphangioleiomyomatosis. Hum Pathol. 2015;46:1685-93 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:10
Andreasen S, Therkildsen M, Grauslund M, Friis Hansen L, Wessel I, Homøe P. Activation of the interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma of the parotid gland. APMIS. 2015;123:706-15 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 3
Ohlmann C, Brecht I, Junker K, van der Zee J, Nistor A, Bohle R, et al. Sclerosing epithelioid fibrosarcoma of the kidney: clinicopathologic and molecular study of a rare neoplasm at a novel location. Ann Diagn Pathol. 2015;19:221-5 pubmed 出版商
  • 免疫组化; 人类
Nakada S, Minato H, Takegami T, Kurose N, Ikeda H, Kobayashi M, et al. NAB2-STAT6 fusion gene analysis in two cases of meningeal solitary fibrous tumor/hemangiopericytoma with late distant metastases. Brain Tumor Pathol. 2015;32:268-74 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:75
Meykler S, Baloch Z, Barroeta J. A case of marginal zone lymphoma with extensive emperipolesis diagnosed on pleural effusion cytology with immunocytochemistry and flow cytometry. Cytopathology. 2016;27:70-2 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hole S, Pedersen A, Hansen S, Lundqvist J, Yde C, Lykkesfeldt A. New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane. Int J Oncol. 2015;46:1481-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Green A, Caracappa D, Benhasouna A, Alshareeda A, Nolan C, Macmillan R, et al. Biological and clinical significance of PARP1 protein expression in breast cancer. Breast Cancer Res Treat. 2015;149:353-62 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gomez Bougie P, Halliez M, Maïga S, Godon C, Kervoëlen C, Pellat Deceunynck C, et al. Curcumin induces cell death of the main molecular myeloma subtypes, particularly the poor prognosis subgroups. Cancer Biol Ther. 2015;16:60-5 pubmed 出版商
  • 免疫组化; 人类
Chow L. Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture. Pathol Res Pract. 2015;211:409-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:80
Vogels R, Vlenterie M, Versleijen Jonkers Y, Ruijter E, Bekers E, Verdijk M, et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. Diagn Pathol. 2014;9:224 pubmed 出版商
  • 流式细胞仪; 人类
Stacchini A, Pacchioni D, Demurtas A, Aliberti S, Cassenti A, Isolato G, et al. Utilility of flow cytometry as ancillary study to improve the cytologic diagnosis of thyroid lymphomas. Cytometry B Clin Cytom. 2015;88:320-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, et al. High frequency of lobular breast cancer in distant metastases to the orbit. Cancer Med. 2015;4:104-11 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:600
Waisberg J, de Souza Viana L, Affonso Junior R, Silva S, Denadai M, Margeotto F, et al. Overexpression of the ITGAV gene is associated with progression and spread of colorectal cancer. Anticancer Res. 2014;34:5599-607 pubmed
  • 免疫组化; 人类; 1:40
Thompson L, Bauer J, Chiosea S, McHugh J, Seethala R, Miettinen M, et al. Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature. Head Neck Pathol. 2015;9:181-95 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 表 2
Syed B, Green A, Nolan C, Morgan D, Ellis I, Cheung K. Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts. PLoS ONE. 2014;9:e100573 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类; 1:300
Rizvi S, Mertens J, Bronk S, Hirsova P, Dai H, Roberts L, et al. Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis. J Biol Chem. 2014;289:22835-49 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Bellas C, Garcia D, Vicente Y, Kilany L, Abraira V, Navarro B, et al. Immunohistochemical and molecular characteristics with prognostic significance in diffuse large B-cell lymphoma. PLoS ONE. 2014;9:e98169 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:40
Capella C, Marando A, Longhi E, Bernasconi B, Finzi G, Parravicini C, et al. Primary gastric Merkel cell carcinoma harboring DNA polyomavirus: first description of an unusual high-grade neuroendocrine carcinoma. Hum Pathol. 2014;45:1310-4 pubmed 出版商
  • 免疫组化; 人类; 1:50
Caramuta S, Lee L, Ozata D, Akçakaya P, Georgii Hemming P, Xie H, et al. Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma. Blood Cancer J. 2013;3:e152 pubmed 出版商
  • 流式细胞仪; 人类; 表 1
Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Bradford C, Kumar B, Bellile E, Lee J, Taylor J, D SILVA N, et al. Biomarkers in advanced larynx cancer. Laryngoscope. 2014;124:179-87 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:600
Viana L, Affonso R, Silva S, Denadai M, Matos D, Salinas de Souza C, et al. Relationship between the expression of the extracellular matrix genes SPARC, SPP1, FN1, ITGA5 and ITGAV and clinicopathological parameters of tumor progression and colorectal cancer dissemination. Oncology. 2013;84:81-91 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300
Hailemariam S, Vosbeck J, Cathomas G, Zlobec I, Mattarelli G, Eichenberger T, et al. Can molecular markers stratify the diagnostic value of high-grade prostatic intraepithelial neoplasia?. Hum Pathol. 2011;42:702-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:30
Snuderl M, Chi S, De Santis S, Stemmer Rachamimov A, Betensky R, De Girolami U, et al. Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas. J Neuropathol Exp Neurol. 2008;67:911-20 pubmed 出版商
Chiche J, Reverso Meinietti J, Mouchotte A, Rubio Patiño C, Mhaidly R, Villa E, et al. GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors. Cell Metab. 2019;29:1243-1257.e10 pubmed 出版商
Turczyk L, Kitowska K, Mieszkowska M, Mieczkowski K, Czaplinska D, Piasecka D, et al. FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ER?-Positive Breast Cancer Cells. Neoplasia. 2017;19:791-804 pubmed 出版商
Ben Younes K, Body S, Costé Ã, Viailly P, Miloudi H, Coudre C, et al. A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. BMC Cancer. 2017;17:538 pubmed 出版商
Suzuki K, Yamamoto K, Arakawa Y, Yamada H, Aiba K, Kitagawa M. Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL. Anticancer Drugs. 2016;27:756-65 pubmed 出版商
Carter B, Mak P, Mak D, Ruvolo V, Schober W, McQueen T, et al. Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells. Oncotarget. 2015;6:30487-99 pubmed 出版商
Lustosa S, Viana L, Affonso R, Silva S, Denadai M, de Toledo S, et al. Expression profiling using a cDNA array and immunohistochemistry for the extracellular matrix genes FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 in colorectal carcinoma progression and dissemination. ScientificWorldJournal. 2014;2014:102541 pubmed 出版商
Trieb K, Sulzbacher I, Kubista B. Bcl-2 correlates with localization but not outcome in human osteosarcoma. Oncol Lett. 2013;6:559-561 pubmed
Lynch J, Somerville T, Spencer G, Huang X, Somervaille T. TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells. Cell Death Dis. 2013;4:e573 pubmed 出版商
Jankovic Velickovic L, Stojnev S, Ristic Petrovic A, Dolicanin Z, Hattori T, Mukaisho K, et al. Pro- and antiapoptotic markers in upper tract urothelial carcinoma associated with Balkan endemic nephropathy. ScientificWorldJournal. 2011;11:1699-711 pubmed 出版商
Tanaka T, Kitabatake K, Iino M, Goto K. Immunohistochemical comparison of CD5, lambda, and kappa expression in primary and recurrent buccal mucosa-associated lymphoid tissue (MALT) lymphomas. Diagn Pathol. 2011;6:82 pubmed 出版商
Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed 出版商
Pighi C, Gu T, Dalai I, Barbi S, Parolini C, Bertolaso A, et al. Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling. Cell Oncol (Dordr). 2011;34:141-53 pubmed 出版商
Hung T, Chen S, Li M, Yeh Y, Hsieh T. Differential effects of concomitant use of vitamins C and E on trophoblast apoptosis and autophagy between normoxia and hypoxia-reoxygenation. PLoS ONE. 2010;5:e12202 pubmed 出版商
Leal R, Ayrizono M, Milanski M, Fagundes J, Moraes J, Meirelles L, et al. Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis. J Transl Med. 2010;8:11 pubmed 出版商
Vendrell J, Robertson K, Ravel P, Bray S, Bajard A, Purdie C, et al. A candidate molecular signature associated with tamoxifen failure in primary breast cancer. Breast Cancer Res. 2008;10:R88 pubmed 出版商
Espíndola M, Corleta O. Bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: a historical cohort study. World J Surg Oncol. 2008;6:65 pubmed 出版商
Bilim V, Yuuki K, Itoi T, Muto A, Kato T, Nagaoka A, et al. Double inhibition of XIAP and Bcl-2 axis is beneficial for retrieving sensitivity of renal cell cancer to apoptosis. Br J Cancer. 2008;98:941-9 pubmed 出版商
公司信息
丹科医疗器械技术服务(上海)有限公司
上海市虹口区四川北路1350号中信泰富申虹广场17楼
china@dako.com
http://www.dako.com/cn/index.htm
86-21-3612 7091
公司总部: 美国
作为Agilent Technologies Company的子品牌,Dako为癌症研究提供高质量的试剂、仪器及软件等产品和服务。