产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Contactin-2, neuronal marker
目录 :
3.1C12
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3.1C12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-冰冻切片
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 s4i
Amin N, Bai G, Klug J, Bonanomi D, Pankratz M, Gifford W, et al. Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. Science. 2015;350:1525-9 pubmed 出版商
Kastriti M, Sargiannidou I, Kleopa K, Karagogeos D. Differential modulation of the juxtaparanodal complex in Multiple Sclerosis. Mol Cell Neurosci. 2015;67:93-103 pubmed 出版商
Favero C, Henshaw R, Grimsley Myers C, Shrestha A, Beier D, Dwyer N. Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain. J Comp Neurol. 2013;521:677-96 pubmed 出版商
Savvaki M, Theodorakis K, Zoupi L, Stamatakis A, Tivodar S, Kyriacou K, et al. The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS. J Neurosci. 2010;30:13943-54 pubmed 出版商
Ma Q, Futagawa T, Yang W, Jiang X, Zeng L, Takeda Y, et al. A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat Cell Biol. 2008;10:283-94 pubmed 出版商
Soares S, Traka M, von Boxberg Y, Bouquet C, Karagogeos D, Nothias F. Neuronal and glial expression of the adhesion molecule TAG-1 is regulated after peripheral nerve lesion or central neurodegeneration of adult nervous system. Eur J Neurosci. 2005;21:1169-80 pubmed
Rickman D, Tyagi R, Zhu X, Bobek M, Song S, Blaivas M, et al. The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas. Cancer Res. 2001;61:2162-8 pubmed
Karagogeos D, Pourquié C, Kyriakopoulou K, Tavian M, Stallcup W, Peault B, et al. Expression of the cell adhesion proteins BEN/SC1/DM-GRASP and TAG-1 defines early steps of axonogenesis in the human spinal cord. J Comp Neurol. 1997;379:415-27 pubmed
Dodd J, Morton S, Karagogeos D, Yamamoto M, Jessell T. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron. 1988;1:105-16 pubmed
Chen E, Chiu A. Early stages in the development of spinal motor neurons. J Comp Neurol. 1992;320:291-303 pubmed
产品信息
内部号码 :
2593
名称 :
3.1C12
Depositor Name :
Jessell, T.M. / Dodd, J. / Brenner-Morton, S.
Depositor Institution :
Center for Neurobiology & Behavior, Columbia University
Date Deposited :
8/15/92
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Contactin-2, neuronal marker
抗原物种 :
大鼠
宿主物种 :
小鼠
抗体亚型 :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
人类, 大鼠
Species Tested (legacy) :
rat, some mouse strains, human
Initial Publication Pubmed ID :
3272160
Depositor Notes (Special Instructions) :
Stains motoneurons, commissural neurons and central afferents of the DRG. Works on western blots of purified TAG-1.
Collections :
Cell adhesion,Cell signaling,Human,Neurodevelopment
搜索关键词 :
Jessell, T.M. / Dodd, J. / Brenner-Morton, S., Contactin-2, neuronal marker, rat, MIgG1, rat/human, Cntn2, Tax1, Tag1, AB_2229763, monoclonal, Cell adhesion/Cell signaling/Human/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation/FFPE, tag-1
抗原分子量 :
Predicted: 104 kDa; Apparent: 120 kDa (nonreducing conditions), 135 kDa (reducing conditions)
基因 :
Cntn2
Alternate Gene Name(s) :
Tax1, Tag1
UniProt数据库编号 :
P22063
抗体登记处号码 :
AB_2229763
Synonyms (Alternate Clone Names) :
1C12
免疫原 :
大鼠(E14-E15)脊髓膜
免疫原序列 :
全长蛋白
克隆性 :
单克隆
Myeloma Strain :
NS-1
表位定位 :
No
Recommended Applications :
FFPE, 免疫荧光, 免疫组化, 免疫沉淀, 免疫印迹
Immunoblotting (legacy) :
yes-purified protein
免疫组化PubMed IDs :
9067833 11280781 15813926
免疫荧光PubMed IDs :
3272160 26070930 15813926 1535349 20962216 31390561
免疫印迹PubMed IDs :
3272160
免疫沉淀PubMed IDs :
3272160 22821687 18278038 20962216
FFPE PubMed IDs :
11280781
其他信息 :
This antibody may work with some mouse strains.
DSHB增长培养基 :
Iscove's
References (legacy) :
Neuron 1, 105-116.; J. Comp. Neurol. 379, 415-427.; Cancer Res. 61, 2162-2168.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。