产品简要
公司名称 :
Developmental Studies Hybridoma Bank
产品类型 :
抗体
产品名称 :
Islet-1 & Islet-2 homeobox
目录 :
39.4D5
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
39.4D5
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼, 家羊, 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, ChIP-Seq, 免疫印迹基因敲除验证
文章摘录数: 175
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 6g
Mangold K, Masek J, He J, Lendahl U, Fuchs E, Andersson E. Highly efficient manipulation of nervous system gene expression with NEPTUNE. Cell Rep Methods. 2021;1: pubmed 出版商
  • 免疫组化; 小鼠; 1:20,000; 图 1e
Landy M, Goyal M, Casey K, Liu C, Lai H. Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell Rep. 2021;34:108913 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 4k, 4l
Stefanovic S, Laforest B, Desvignes J, Lescroart F, Argiro L, Maurel Zaffran C, et al. Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 2b
Lee H, Lee H, Lee B, Gerovska D, Park S, Zaehres H, et al. Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:100; 图 1s1a
Kantarci H, Gou Y, Riley B. The Warburg Effect and lactate signaling augment Fgf-MAPK to promote sensory-neural development in the otic vesicle. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:20; 图 3a
Hael C, Rojo D, Orquera D, Low M, Rubinstein M. The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. Mol Metab. 2020;34:43-53 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1d
Suter T, Blagburn S, Fisher S, Anderson Keightly H, D Elia K, Jaworski A. TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. 2020;30:1164-1177.e7 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:300; 图 s3d
Wan Y, Wei Z, Looger L, Koyama M, Druckmann S, Keller P. Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit. Cell. 2019;179:355-372.e23 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 2f
Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, et al. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019;364: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 6f
Tulloch A, Teo S, Carvajal B, Tessier Lavigne M, Jaworski A. Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. J Comp Neurol. 2019;527:2948-2972 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:10; 图 s4b
  • ChIP-Seq; 小鼠; 图 5b
  • 染色质免疫沉淀 ; 小鼠; 图 s7c
  • 免疫沉淀; 小鼠; 图 5k
  • 免疫印迹; 小鼠; 1:10; 图 5a
Gao R, Liang X, Cheedipudi S, Cordero J, Jiang X, Zhang Q, et al. Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate. Cell Res. 2019;29:486-501 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 5d
Rajderkar S, Mann J, Panaretos C, Yumoto K, Li H, Mishina Y, et al. Trim33 is required for appropriate development of pre-cardiogenic mesoderm. Dev Biol. 2019;450:101-114 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6f
Wizeman J, Guo Q, Wilion E, LI J. Specification of diverse cell types during early neurogenesis of the mouse cerebellum. elife. 2019;8: pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:20; 图 6a
  • 流式细胞仪; 人类; 1:100; 图 7e
Sahara M, Santoro F, Sohlmér J, Zhou C, Witman N, Leung C, et al. Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. Dev Cell. 2019;48:475-490.e7 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1a
Marcucci F, Soares C, Mason C. Distinct timing of neurogenesis of ipsilateral and contralateral retinal ganglion cells. J Comp Neurol. 2019;527:212-224 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150; 图 3w
Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero Jimenez A, et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. elife. 2018;7: pubmed 出版商
  • 免疫组化; 小鼠; 图 2c
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 4c
Miesfeld J, Glaser T, Brown N. The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody. Gene Expr Patterns. 2018;27:114-121 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 6d
Tahara N, Akiyama R, Theisen J, Kawakami H, Wong J, Garry D, et al. Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules. Dev Biol. 2018;434:74-83 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 1i
Tinterri A, Deck M, Keita M, Mailhes C, Rubin A, Kessaris N, et al. Tangential migration of corridor guidepost neurons contributes to anxiety circuits. J Comp Neurol. 2018;526:397-411 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2h
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al. A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. Cell Stem Cell. 2017;21:399-410.e7 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 3e
Ohman Gault L, Huang T, KRIMM R. The transcription factor Phox2b distinguishes between oral and non-oral sensory neurons in the geniculate ganglion. J Comp Neurol. 2017;525:3935-3950 pubmed 出版商
  • 免疫组化-自由浮动切片; 非洲爪蛙; 1:500; 表 2
Moreno N, González A. Pattern of Neurogenesis and Identification of Neuronal Progenitor Subtypes during Pallial Development in Xenopus laevis. Front Neuroanat. 2017;11:24 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1b
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 st4
Qi Y, Zhang X, Renier N, Wu Z, Atkin T, Sun Z, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017;35:154-163 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:10; 图 1a
Witzel H, Cheedipudi S, Gao R, Stainier D, Dobreva G. Isl2b regulates anterior second heart field development in zebrafish. Sci Rep. 2017;7:41043 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1b
Maltabe V, Barka E, Kontonika M, Florou D, Kouvara Pritsouli M, Roumpi M, et al. Isolation of an ES-Derived Cardiovascular Multipotent Cell Population Based on VE-Cadherin Promoter Activity. Stem Cells Int. 2016;2016:8305624 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 5e
Kahn B, Corman T, Lovelace K, Hong M, Krauss R, Epstein D. Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia. Dis Model Mech. 2017;10:29-37 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 s5k
Li Y, Tzatzalos E, Kwan K, Grumet M, Cai L. Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development. Sci Rep. 2016;6:38665 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 s9
Espinosa Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson W, et al. The sacral autonomic outflow is sympathetic. Science. 2016;354:893-897 pubmed
  • 流式细胞仪; 人类; 1:200; 图 s9c
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed 出版商
  • 免疫组化; 小鼠; 图 5a
Junge H, Yung A, Goodrich L, Chen Z. Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord. Neural Dev. 2016;11:19 pubmed
  • 免疫组化; 小鼠; 图 3s2
Leggere J, Saito Y, Darnell R, Tessier Lavigne M, Junge H, Chen Z. NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 4
Baleriola J, Álvarez Lindo N, de la Villa P, Bernad A, Blanco L, Suárez T, et al. Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina. Sci Rep. 2016;6:25928 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 1a
Feng J, Xian Q, Guan T, Hu J, Wang M, Huang Y, et al. Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex. 2016;26:3323-34 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 6
Iwai Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C. Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. J Comp Neurol. 2016;524:3696-3716 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1
  • 免疫组化; 斑马鱼; 1:10; 图 s4
Davey C, Mathewson A, Moens C. PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet. 2016;12:e1005934 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 s4
Fattahi F, Steinbeck J, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, et al. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016;531:105-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 表 1
de Souza C, Nivison Smith L, Christie D, Polkinghorne P, McGhee C, Kalloniatis M, et al. Macromolecular markers in normal human retina and applications to human retinal disease. Exp Eye Res. 2016;150:135-48 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250-1:500; 图 1
Gayet Primo J, Puthussery T. Alterations in Kainate Receptor and TRPM1 Localization in Bipolar Cells after Retinal Photoreceptor Degeneration. Front Cell Neurosci. 2015;9:486 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:5000; 表 1
Pirson M, Debrulle S, Clippe A, Clotman F, Knoops B. Thioredoxin-2 Modulates Neuronal Programmed Cell Death in the Embryonic Chick Spinal Cord in Basal and Target-Deprived Conditions. PLoS ONE. 2015;10:e0142280 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 1c
  • 免疫组化; 小鼠; 1:1000; 图 2
  • 免疫印迹; 小鼠; 1:1000; 图 1a
  • 免疫组化; 人类; 图 5d
Galloway J, Bethea M, Liu Y, Underwood R, Mobley J, Hunter C. SSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes. Mol Endocrinol. 2015;29:1774-86 pubmed 出版商
  • 免疫组化; 小鼠; 图 6
Hua Z, Emiliani F, Nathans J. Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Neural Dev. 2015;10:21 pubmed 出版商
  • 免疫组化; 小鼠; 1:50
Huettl R, Eckstein S, Stahl T, Petricca S, Ninkovic J, Götz M, et al. Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 2016;413:86-103 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 5
Lenzi J, De Santis R, de Turris V, Morlando M, Laneve P, Calvo A, et al. ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneurons. Dis Model Mech. 2015;8:755-66 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 1j
Watanabe S, Sanuki R, Sugita Y, Imai W, Yamazaki R, Kozuka T, et al. Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. J Neurosci. 2015;35:8004-20 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2
Adams K, Rousso D, Umbach J, Novitch B. Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015;6:6778 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:20; 图 1
Holzmann J, Hennchen M, Rohrer H. Prox1 identifies proliferating neuroblasts and nascent neurons during neurogenesis in sympathetic ganglia. Dev Neurobiol. 2015;75:1352-67 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 5
Maury Y, Côme J, Piskorowski R, Salah Mohellibi N, Chevaleyre V, Peschanski M, et al. Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes. Nat Biotechnol. 2015;33:89-96 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 5a
Zou M, Luo H, Xiang M. Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015;244:86-97 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
Whitney I, Keeley P, St John A, Kautzman A, Kay J, Reese B. Sox2 regulates cholinergic amacrine cell positioning and dendritic stratification in the retina. J Neurosci. 2014;34:10109-21 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000
  • 染色质免疫沉淀 ; 小鼠
  • EMSA; 小鼠
Ediger B, Du A, Liu J, Hunter C, Walp E, Schug J, et al. Islet-1 Is essential for pancreatic ?-cell function. Diabetes. 2014;63:4206-17 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 1:20
  • 免疫组化; 鸡; 1:20
Lee K, Seo J, Shin J, Ji E, Roh J, Kim J, et al. Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system. Proc Natl Acad Sci U S A. 2014;111:2794-9 pubmed 出版商
  • 免疫组化-自由浮动切片; 非洲爪蛙; 1:500
Dominguez L, González A, Moreno N. Characterization of the hypothalamus of Xenopus laevis during development. II. The basal regions. J Comp Neurol. 2014;522:1102-31 pubmed 出版商
  • 免疫细胞化学; 家羊; 图 5
Weber B, Kehl D, Bleul U, Behr L, Sammut S, Frese L, et al. In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells. J Tissue Eng Regen Med. 2016;10:52-70 pubmed 出版商
  • 免疫组化; 小鼠; 图 2
Le Bras B, Fréal A, Czarnecki A, Legendre P, Bullier E, Komada M, et al. In vivo assembly of the axon initial segment in motor neurons. Brain Struct Funct. 2014;219:1433-50 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:200
Nivison Smith L, Sun D, Fletcher E, Marc R, Kalloniatis M. Mapping kainate activation of inner neurons in the rat retina. J Comp Neurol. 2013;521:2416-38 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Favero C, Henshaw R, Grimsley Myers C, Shrestha A, Beier D, Dwyer N. Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain. J Comp Neurol. 2013;521:677-96 pubmed 出版商
Sansa A, Hidalgo I, Miralles M, de la Fuente S, Perez Garcia M, Munell F, et al. Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons. Acta Neuropathol Commun. 2021;9:122 pubmed 出版商
Danesin C, Darche Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, et al. Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. Sci Rep. 2021;11:118 pubmed 出版商
Chhabra S, Liu L, Goh R, Kong X, Warmflash A. Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids. PLoS Biol. 2019;17:e3000498 pubmed 出版商
Dong X, Xie X, Guo L, Xu J, Xu M, Liang G, et al. Generation and characterization of Lhx4tdT reporter knock-in and Lhx4loxP conditional knockout mice. Genesis. 2019;57:e23328 pubmed 出版商
Schick E, McCaffery S, Keblish E, Thakurdin C, Emerson M. Lineage tracing analysis of cone photoreceptor associated cis-regulatory elements in the developing chicken retina. Sci Rep. 2019;9:9358 pubmed 出版商
De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone M, et al. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;27:3818-3831.e5 pubmed 出版商
Murcia Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valiño A, et al. A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019;29:1149-1160.e4 pubmed 出版商
Jacquier A, Risson V, Schaeffer L. Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons. J Vis Exp. 2019;: pubmed 出版商
Jia G, Preussner J, Chen X, Guenther S, Yuan X, Yekelchyk M, et al. Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement. Nat Commun. 2018;9:4877 pubmed 出版商
Yen Y, Hsieh W, Tsai Y, Lü Y, Liau E, Hsu H, et al. Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity. elife. 2018;7: pubmed 出版商
Pane L, Fulcoli F, Cirino A, Altomonte A, Ferrentino R, Bilio M, et al. Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer. Dis Model Mech. 2018;11: pubmed 出版商
Ghosh P, Maurer J, SAGERSTROM C. Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Dev. 2018;13:13 pubmed 出版商
Washausen S, Knabe W. Lateral line placodes of aquatic vertebrates are evolutionarily conserved in mammals. Biol Open. 2018;7: pubmed 出版商
Ray T, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert S, et al. Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. elife. 2018;7: pubmed 出版商
Maurer J, SAGERSTROM C. A parental requirement for dual-specificity phosphatase 6 in zebrafish. BMC Dev Biol. 2018;18:6 pubmed 出版商
Capauto D, Colantoni A, Lu L, Santini T, Peruzzi G, Biscarini S, et al. A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons. Mol Neurobiol. 2018;55:7635-7651 pubmed 出版商
Gou Y, Vemaraju S, Sweet E, Kwon H, Riley B. sox2 and sox3 Play unique roles in development of hair cells and neurons in the zebrafish inner ear. Dev Biol. 2018;435:73-83 pubmed 出版商
Boubakar L, Falk J, Ducuing H, Thoinet K, Reynaud F, Derrington E, et al. Molecular Memory of Morphologies by Septins during Neuron Generation Allows Early Polarity Inheritance. Neuron. 2017;95:834-851.e5 pubmed 出版商
Huang C, Lien C, Cheng C, Yen T, Chen C, Tsaur M. K+ Channel Kv3.4 Is Essential for Axon Growth by Limiting the Influx of Ca2+ into Growth Cones. J Neurosci. 2017;37:4433-4449 pubmed 出版商
Park K, Randazzo G, Jones K, Brzezinski J. Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017;58:1137-1150 pubmed 出版商
Dvorakova M, Jahan I, Macova I, Chumak T, Bohuslavova R, Syka J, et al. Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance. Sci Rep. 2016;6:38253 pubmed 出版商
Ranga A, Girgin M, Meinhardt A, Eberle D, Caiazzo M, Tanaka E, et al. Neural tube morphogenesis in synthetic 3D microenvironments. Proc Natl Acad Sci U S A. 2016;113:E6831-E6839 pubmed
Saller M, Huettl R, Hanuschick P, Amend A, Alberton P, Aszodi A, et al. The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016;129:3295-308 pubmed 出版商
Johnson K, Barragan J, Bashiruddin S, Smith C, Tyrrell C, Parsons M, et al. Gfap-positive radial glial cells are an essential progenitor population for later-born neurons and glia in the zebrafish spinal cord. Glia. 2016;64:1170-89 pubmed 出版商
Bohuslavova R, Dodd N, Macova I, Chumak T, Horak M, Syka J, et al. Pax2-Islet1 Transgenic Mice Are Hyperactive and Have Altered Cerebellar Foliation. Mol Neurobiol. 2017;54:1352-1368 pubmed 出版商
Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, et al. Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232 pubmed 出版商
Sato S, Yajima H, Furuta Y, Ikeda K, Kawakami K. Activation of Six1 Expression in Vertebrate Sensory Neurons. PLoS ONE. 2015;10:e0136666 pubmed 出版商
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Bejarano Escobar R, Blasco M, DeGrip W, Oyola Velasco J, Martin Partido G, Francisco Morcillo J. Eye development and retinal differentiation in an altricial fish species, the senegalese sole (Solea senegalensis, Kaup 1858). J Exp Zool B Mol Dev Evol. 2010;314:580-605 pubmed 出版商
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产品信息
内部号码 :
4236
名称 :
39.4D5
Depositor Name :
Jessell, T.M. / Brenner-Morton, S.
Depositor Institution :
HHMI/Columbia University
Depositor Website :
http://sklad.cumc.columbia.edu/jessell/
Date Deposited :
11/3/95
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
抗原 :
Islet-1 & Islet-2 homeobox
抗原物种 :
大鼠
宿主物种 :
小鼠
抗体亚型 :
MIgG2b
Isotype for catalog (legacy) :
IgG2b
Positive Tested Species Reactivity :
Chicken,Ferret,Fish,Frog,Human,Mouse,Rat,Zebrafish,altricial fish larva
Species Tested (legacy) :
all tested (rat, mouse, chicken, frog, zebra fish, human) are positive
Initial Publication Pubmed ID :
1350865 7528105
Depositor Notes (Special Instructions) :
MN, DRG & other nuclei characterized extensively by immunocytochemistry; works in paraformaldehyde-fixed and paraffin-embedded tissue; does not work in methanol or acetone (see Sanders et al., 2003, and Georgia et al., 2006) TEST
Collections :
Cardiac development,Human,Neurodevelopment,Transcription factors,Xenopus
搜索关键词 :
Jessell, Thomas M / Brenner-Morton, Susan, Islet-1 Islet-2 homeobox, Rat, MIgG2b, Rat/Mouse/Chicken/Frog/Zebrafish/Ferret/Human, Isl1 & Isl2, ISL1, ISL LIM homeobox 1, ISL2; ISL LIM homeobox 2, AB_2314683, Monoclonal
抗原分子量 :
Predicted: 39kDa; Apparent: 39kDa
基因 :
Isl1 & Isl2
Alternate Gene Name(s) :
ISL1, ISL LIM同源异形盒1, ISL2;ISL LIM同源异形盒2
UniProt数据库编号 :
P61374 P50480
抗体登记处号码 :
AB_2314683
Synonyms (Alternate Clone Names) :
抗islet1;抗isl1;抗islet2;抗isl2
免疫原 :
Recombinant fusion protein containing aa 178-349 of Isl1 protein (C-terminus)
免疫原序列 :
Partial protein
克隆性 :
单克隆
Myeloma Strain :
NS1
表位定位 :
Yes
Epitope Location or Sequence :
aa 178-349 of Isl1 protein
表位定位Pubmed登录号 :
1350865
Recommended Applications :
Chromatin Immunoprecipitation,Gel Supershift,Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
yes
免疫组化PubMed IDs :
14638744 16899237 7528105 8929535 10491257 9890440 10864957 11336495 11596060 11877374 12121626 12357432 14656152 14638744 14993186 14973 11818560[289 15464286 16260730 16672347 16899237 16815098 19571884 21334323 22318233 12150931 8124714 10704832 9507132 15614781 22833130 11301207 15525781 22275004 23077655 22554084 21689645 21471154 22003118 20203184 20146251 20080554 19924821 20549713 19379735 29848488
免疫荧光PubMed IDs :
20549713 19379735 28817802 24760871 27100776 31313880 30311912
免疫印迹PubMed IDs :
21388963
染色质免疫沉淀 PubMed IDs :
24674670
FFPE PubMed IDs :
29848488
Gel Supershift Pubmed IDs :
19502415
PubMed IDs :
22275004 23077655 22554084 21689645 21471154 22003118 20203184 20146251 20080554 19924821
其他信息 :
also detects Islet-2. The protein region used for immunization lacks the LIM motifs shared with other proteins.
DSHB增长培养基 :
Iscove's
References (legacy) :
Science 256, 1555-1560.; Cell 73, 673-686.; Cell 87, 661-673.; Dev. Biol. 214, 60-71.; J. Neurosci. Res. 55, 119-126.; J. Neurosci. 20(13), 4992-5000.; Dev. Biol. 233, 271-290.; J. Comp. Neurol. 439, 368-383.; Genes Dev. 16, 548-553.; Curr. Biol. 12, 1157-1163.; J. Comp. Neurol. 453, 57-70.; Cell 110, 237-249.; Biotechnol. Prog. 19, 1756-1761.; Invest. Ophthalmol. Vis. Sci. 44(12), 5404-5409.; Development 131, 1319-1330.; Development 131, 1017-1028.; J. Neurosci. 24(44), 9962-9970.; Neuroscience 128, 785-796.; Dev. Dyn. 232, 313-324.; PNAS 102(45), 16421-16425.; Development 133, 2137-2147.; Dev. Biol. 298, 22-31.; Genes Dev. 21, 531-536.; Genes Dev. 22, 3320-3334.; Gene Expr. Patterns 7, 57-65.; Dev. Biol. 353, 10-18.; Hear. Res. 278, 86-95.; J. Biol. Chem. 287(24), 20483-20489.; Development 139, 1125-1132.; J. Biol. Chem. 287(29), 24255-24262.; J. Comp. Neurol. 520, 330-363.
公司信息
Developmental Studies Hybridoma Bank
University of Iowa
dshb@uiowa.edu
http://dshb.biology.uiowa.edu
公司总部: 美国
Developmental Studies Hybridoma Bank (DSHB) 是NIH于1996年创办的国家机构,为生命科学研究领域及诊断领域,提供高质量的抗体等产品。